CAS 70797-11-4

Cefpiramide

Description:

Cefpiramide is a broad-spectrum cephalosporin antibiotic, primarily used for its antibacterial properties against a variety of Gram-positive and Gram-negative bacteria. It is characterized by its beta-lactam structure, which is essential for its mechanism of action, as it inhibits bacterial cell wall synthesis. Cefpiramide is typically administered via injection and is effective in treating serious infections, including those caused by resistant strains. The compound exhibits good stability against certain beta-lactamases, which enhances its efficacy against resistant bacteria. Its pharmacokinetics involve distribution throughout body tissues, with a relatively long half-life, allowing for less frequent dosing. Common side effects may include gastrointestinal disturbances and allergic reactions, similar to other antibiotics in its class. Cefpiramide is often used in clinical settings for severe infections, particularly in hospitalized patients, and is subject to careful monitoring due to potential resistance development. As with all antibiotics, appropriate use is crucial to minimize the risk of resistance and ensure therapeutic effectiveness.

Formula: C₂₅H₂₄N₈O₇S₂

InChI: InChI=1S/C25H24N8O7S2/c1-11-7-16(35)15(8-26-11)20(36)27-17(12-3-5-14(34)6-4-12)21(37)28-18-22(38)33-19(24(39)40)13(9-41-23(18)33)10-42-25-29-30-31-32(25)2/h3-8,17-18,23,34H,9-10H2,1-2H3,(H,26,35)(H,27,36)(H,28,37)(H,39,40)/t17-,18-,23-/m1/s1

InChI key: InChIKey=PWAUCHMQEXVFJR-PMAPCBKXSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](NC(=O)C=3C(O)=CC(C)=NC3)C4=CC=C(O)C=C4)=O)C2=O)(SCC1CSC=5N(C)N=NN5)[H]

Synonyms:

• (6R)-7-{[(2R)-2-(4-hydroxyphenyl)-2-{[(6-methyl-4-oxo-1,4-dihydropyridin-3-yl)carbonyl]amino}acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-[[(2R)-2-[[(4-Hydroxy-6-methyl-3-pyridinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2R)-2-(4-hydroxyphenyl)-2-{[(6-methyl-4-oxo-1,4-dihydropyridin-3-yl)carbonyl]amino}acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(4-hydroxyphenyl){[(6-methyl-4-oxo-1,4-dihydropyridin-3-yl)carbonyl]amino}acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-[6α,7β(R*)]]-
• Cefpiramide acid
• Cefpiramide

Cefpiramide acid

CAS: 70797-11-4

Cefpiramide acid (Cefpiramidum) is a third-generation cephalosporin antibiotic.

Formula: C₂₅H₂₄N₈O₇S₂

Purity: 97.40%

Color and Shape: White Or Off-White Crystalline Powder

Molecular weight: 612.637

Ref: TM-T0138

Cefpiramide

CAS: 70797-11-4

Formula: C₂₅H₂₄N₈O₇S₂

Molecular weight: 612.64

Ref: 7W-GP3555

Cefpiramide acid

CAS: 70797-11-4

Cefpiramide acid

Formula: C₂₅H₂₄N₈O₇S₂

Purity: 97%

Molecular weight: 612.64

Ref: 54-BUP11915

Cefpiramide

CAS: 70797-11-4

Formula: C₂₅H₂₄N₈O₇S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 612.6375

Ref: IN-DA00IC3Q

Cefpiramide

Controlled Product

CAS: 70797-11-4

Applications Cefpiramide is used as a β-lactam antibiotic.
References Tsuji, A. et al.: Biochem. Pharmacol., 35, 151 (1986); Kato, Y. et al.: Drug Metab. Disp., 36, 1088 (2008);

Formula: C₂₅H₂₄N₈O₇S₂

Color and Shape: Neat

Molecular weight: 612.64

Ref: TR-C243400

Cefpiramide

CAS: 70797-11-4

(6R,7R)-7-((R)-2-(4-hydroxy-6-methylnicotinamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula: C₂₅H₂₄N₈O₇S₂

Purity: 97%

Molecular weight: 612.64

Ref: IN-DG22310

Cefpiramide

CAS: 70797-11-4

Antibiotics nesoi

Formula: C₂₅H₂₄N₈O₇S₂

Color and Shape: Crystals

Molecular weight: 612.12094

Ref: 45-1098118