CAS 70904-56-2

Kyotorphin

Description:

Kyotorphin is a dipeptide composed of the amino acids tyrosine and arginine, known for its role in modulating pain and exhibiting analgesic properties. It is classified as a neuropeptide and is primarily found in the brain and spinal cord, where it is believed to interact with opioid receptors, contributing to pain relief mechanisms. Kyotorphin has been studied for its potential therapeutic applications in pain management and neuroprotection. Its structure allows it to cross the blood-brain barrier, enhancing its effectiveness in central nervous system functions. Additionally, kyotorphin may influence various physiological processes, including mood regulation and stress response. While research continues to explore its full range of biological activities, kyotorphin's unique properties make it a subject of interest in both pharmacology and neuroscience. As with many peptides, its stability and bioavailability can be influenced by factors such as administration route and formulation.

Formula: C₁₅H₂₃N₅O₄

InChI: InChI=1S/C15H23N5O4/c16-11(8-9-3-5-10(21)6-4-9)13(22)20-12(14(23)24)2-1-7-19-15(17)18/h3-6,11-12,21H,1-2,7-8,16H2,(H,20,22)(H,23,24)(H4,17,18,19)/t11-,12-/m0/s1

InChI key: InChIKey=JXNRXNCCROJZFB-RYUDHWBXSA-N

SMILES: C([C@@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)N)C1=CC=C(O)C=C1

Synonyms:

• 124: PN: EP2161028 PAGE: 10 claimed protein
• 1714: PN: WO2007124090 PAGE: 83 claimed protein
• 177: PN: WO2012013136 SEQID: 78 unclaimed protein
• <span class="text-smallcaps">L</smallcap>-Arginine, <smallcap>L</span>-tyrosyl-
• <span class="text-smallcaps">L</smallcap>-Arginine, N²-<smallcap>L</span>-tyrosyl-
• <span class="text-smallcaps">L</smallcap>-Tyrosyl-<smallcap>L</span>-arginine
• Arginine, N²-tyrosyl-
• Dipeptide 1
• Kiotorphin
• Kyotorphin
• L-Tyrosyl-L-arginine
• L-Arginine, N2-L-tyrosyl-
• L-Arginine, L-tyrosyl-

Kyotorphin

CAS: 70904-56-2

The analgesic, opioid dipeptide kyotorphin was first identified in bovine brain. Administered intracisternally to mice, kyotorphin had an analgesic effect which was about 4.2 times more potent than that of Met-enkephalin. Kyotorphin modulates the Na⁺/Cl⁻dependant opioid peptide transporter.

Formula: C₁₅H₂₃N₅O₄

Purity: > 98%

Color and Shape: White

Molecular weight: 337.38

Ref: 01-4003049

Kyotorphin

CAS: 70904-56-2

Kyotorphin is a Morphine-like dipeptide.

Formula: C₁₅H₂₃N₅O₄

Color and Shape: Solid

Molecular weight: 337.38

Ref: TM-T20172