CAS 71-62-5: Veratridine
Description:Veratridine is a naturally occurring alkaloid derived from the seeds of the plant genus *Veratrum*, particularly *Veratrum album*. It is classified as a potent neurotoxin and is known for its ability to affect sodium channels in excitable membranes, leading to increased neuronal excitability. Veratridine is a white to off-white crystalline powder that is soluble in organic solvents like ethanol and chloroform but has limited solubility in water. Its chemical structure features a complex bicyclic framework, which contributes to its biological activity. The compound is primarily used in research settings to study ion channel function and neurophysiology. Due to its toxic properties, veratridine must be handled with care, as it can cause severe physiological effects, including cardiovascular and respiratory disturbances, when ingested or improperly handled. Safety precautions are essential when working with this substance in laboratory environments.
Formula:C36H51NO11
InChI:InChI=1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29(39)20-7-8-21(45-4)22(14-20)46-5/h7-8,14,19,23-28,38,40-44H,6,9-13,15-18H2,1-5H3/t19-,23-,24-,25-,26-,27-,28-,30-,31+,32+,33+,34+,35-,36-/m0/s1
InChI key:InChIKey=FVECELJHCSPHKY-YFUMOZOISA-N
SMILES:O=C(OC1CCC2(C)C3CCC4C5(O)CC(O)C6(O)C(CN7CC(C)CCC7C6(O)C)C5(O)CC42OC13O)C8=CC=C(OC)C(OC)=C8
- Synonyms:
- 3-Veratrate De 4,9-Epoxycevane-3Β,4Α,12,14,16Β,17,20-Heptol
- 3-Veratrato De 4,9-Epoxicevano-3Β,4Α,12,14,16Β,17,20-Heptol
- 3-Veratroylveracevine
- 4,9-Epoxycevan-3β,4α,12,14,16β,17,20-heptol-3-veratrumat
- 4,9-Epoxycevane-3Β,4Α,12,14,16Β,17,20-Heptol 3-Veratrate
- Nsc 7524
- Veracevine, veratrate
- Veratridine
- Veratrine
- Veratrine (amorphous)
- See more synonyms
- Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-, 3-(3,4-dimethoxybenzoate), (3β,4α,16β)-
