CAS 71901-21-8

N-formyl-nle-leu-phe-nle-tyr-lys

Description:

N-formyl-nle-leu-phe-nle-tyr-lys, with the CAS number 71901-21-8, is a synthetic peptide that is characterized by its specific sequence of amino acids. This compound features a formyl group attached to the N-terminal, which can influence its biological activity and stability. The presence of non-standard amino acids, such as nle (norleucine), contributes to its unique properties, potentially enhancing its resistance to enzymatic degradation compared to peptides composed solely of standard amino acids. The sequence includes hydrophobic and polar residues, which may affect its solubility and interaction with biological membranes. Peptides like this one are often studied for their potential roles in pharmacology, particularly in the development of therapeutic agents or as research tools in biochemistry. Additionally, the structural characteristics of this peptide can influence its conformation and, consequently, its biological function, making it a subject of interest in peptide chemistry and drug design.

Formula: C₄₃H₆₅N₇O₉

InChI: InChI=1/C43H65N7O9/c1-5-7-16-32(45-27-51)38(53)48-35(24-28(3)4)40(55)50-36(25-29-14-10-9-11-15-29)41(56)46-33(17-8-6-2)39(54)49-37(26-30-19-21-31(52)22-20-30)42(57)47-34(43(58)59)18-12-13-23-44/h9-11,14-15,19-22,27-28,32-37,52H,5-8,12-13,16-18,23-26,44H2,1-4H3,(H,45,51)(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)(H,58,59)/t32-,33-,34-,35-,36-,37-/m0/s1

SMILES: CCCC[C@@H](C(=N[C@@H](CC(C)C)C(=N[C@@H](Cc1ccccc1)C(=N[C@@H](CCCC)C(=N[C@@H](Cc1ccc(cc1)O)C(=N[C@@H](CCCCN)C(=O)O)O)O)O)O)O)N=CO

Synonyms:

• For-Nle-Leu-Phe-Nle-Tyr-Lys-OH
• N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys

CAS: 71901-21-8

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA is a formyl peptide receptor (FPR) agonist.

Formula: C₄₃H₆₅N₇O₉

Purity: 98%

Color and Shape: White Powder

Molecular weight: 824.02

Ref: TM-TQ0143

C-MYC PEPTIDE EPITOPE TFA

CAS: 71901-21-8

C-MYC PEPTIDE EPITOPE TFA

Purity: ≥98%

Molecular weight: 1317.32g/mol

Ref: 54-BUP20502

For-Nle-Leu-Phe-Nle-Tyr-Lys-OH

CAS: 71901-21-8

For-Nle-Leu-Phe-Nle-Tyr-Lys-OH is an amino acid sequence that is a proteolytic fragment of the erythrocyte membrane protein band 3. It has been shown to be able to inhibit the activity of cytosolic calcium and actin filament polymerization, as well as inhibiting apoptosis in human polymorphonuclear leukocytes (PMNL). This compound has been found to be effective in preventing uptake of bacteria by neutrophils, which may be due to its ability to alter the pH gradient across the membrane and increase intracellular calcium levels. For-Nle-Leu-Phe-Nle-Tyr-Lys-OH also inhibits diacylglycerol synthesis, which may contribute to its antiinflammatory effects.

Formula: C₄₃H₆₅N₇O₉

Purity: Min. 95%

Molecular weight: 824.02 g/mol

Ref: 3D-FF108866