CAS 72-33-3

mestranol

Description:

Mestranol is a synthetic estrogen, primarily used in hormonal contraceptives and hormone replacement therapy. It is a white to off-white crystalline powder that is poorly soluble in water but soluble in organic solvents like ethanol and chloroform. Mestranol is characterized by its chemical formula, which includes a phenolic hydroxyl group, contributing to its estrogenic activity. The substance acts by binding to estrogen receptors, influencing various physiological processes, including the regulation of the menstrual cycle and maintenance of secondary sexual characteristics. Mestranol is often administered in combination with progestins in oral contraceptive formulations. Its pharmacokinetics involve hepatic metabolism, and it is typically excreted in urine. While effective for its intended uses, mestranol can have side effects, including nausea, headaches, and an increased risk of thromboembolic events. As with any hormonal treatment, its use should be carefully monitored by healthcare professionals to mitigate potential risks and ensure patient safety.

Formula: C₂₁H₂₆O₂

InChI: InChI=1/C29H52/c1-7-22(20(2)3)12-11-21(4)25-15-16-26-24-14-13-23-10-8-9-18-28(23,5)27(24)17-19-29(25,26)6/h20-27H,7-19H2,1-6H3/t21-,22-,23+,24+,25-,26+,27+,28+,29-/m1/s1

InChI key: InChIKey=IMSSROKUHAOUJS-MJCUULBUSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC)=CC4)(CC1)[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (17Beta)-17-Ethynyl-3-Methoxyestra-1,3,5(10)-Trien-17-Ol
• (17α)-3-Methoxy-19-norpregna-1,3,5-(10)-trien-20-yn-17-ol
• (5Beta)-Stigmastane
• (8R,9S,13S,14S,17R)-17-Ethynyl-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol
• 17-Ethynyl-3-Methoxyestra-1,3,5(10)-Trien-17-Ol
• 17-Ethynyl-3-methoxy-1,3,5(10)-estratrien-17β-o1
• 17-Ethynyl-3-methoxyestra-1,3,5(10)-trien-17β-ol
• 17-Ethynylestradiol 3-methyl ether
• 17-eth-1-ynyl-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol
• 17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether
• 17α-Ethinylestradiol 3-methyl ether
• 17α-Ethynyl-3-methoxy-1,3,5(10)-estratrien-17β-ol
• 17α-Ethynyl-3-methoxy-17β-hydroxy-Δ1,3,5(10)-estratriene
• 17α-Ethynyl-3-methoxy-17β-hydroxy-Δ^1,3,5(10)-estratriene
• 17α-Ethynylestradiol 3-methyl ether
• 17α-Ethynylestradiol methyl ether
• 19-Nor-17α-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-
• 19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, (17α)-
• 19-Norpregna-1,3,5(10)-trien-20-yne-17-ol, 3-methoxy-, (17α)-
• 3-Methoxy-17α-ethinylestradiol
• 3-Methoxy-17α-ethynylestradiol
• 3-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yn-17-ol
• 3-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yn-17β-ol
• 3-Methoxyethynylestradiol
• 3-Methylethynylestradiol
• 3-O-Methyl-17α-ethynylestradiol
• 3-O-Methylethynylestradiol
• 33355
• 8027 C. B.
• Devocin
• Ee 3Me
• Ethinylestradiol 3-methyl ether
• Ethynylestradiol 3-methyl ether
• Ethynylestradiol 3-monomethyl ether
• Ethynylestradiol methyl ether
• Inostral
• Menophase
• Norquen
• Nsc 84032
• Ovastol
• Sc 4725
• δ-MVE
• 17aethynyl-estradiol-3-methylether
• 17ALPHA-ETHYNYLESTRADIOL 3-METHYL ETHER
• 3-METHOXY-17ALPHA-ETHYNYLESTRADIOL
• 17-ALPHA-ETHINYL-OESTRADIOL-3-METHYL ETHER
• 17ALPHA-ETHYNYL-1,3,5(10)-ESTRATRIENE-3,17BETA-DIOL 3-METHYL ETHER
• ETHINYLESTRADIOL METHYL ETHER
• (17A)-3-METHOXY-19-NORPREGMA-1,3,5(10)-TRIEN-20-YN-17-OL
• 1,3,5(10)-ESTRATRIEN-17-ALPHA-ETHYNYL-3,17-BETA-DIOL 3-METHYL ETHER
• 17A-ETHYNYLESTRADIOL 3-METHYLTHER
• (+)-17alpha-Ethynyl-17beta-hydroxy-3-methoxy-1,3,5(10)-oestratriene
• (+)-17alpha-Ethynyl-17beta-hydroxy-3-methoxy-1,3,5(10)-estratriene
• (17-alpha)-3-methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol
• 17alpha-19-Norpregna-1,3,5(10)-trien-20-yn-17-ol,3-methoxy-
• (+)-17-alpha-ethynyl-17-beta-hydroxy-3-methoxy-1,3,5(10)-oestratriene
• 17alpha-19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-
• MESTRANOL

MESTRANOL CRS

CAS: 72-33-3

MESTRANOL CRS

Formula: C₂₁H₂₆O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 310.4299

Ref: 41-M0600000

Mestranol

CAS: 72-33-3

Estrogens and progestins

Formula: C₂₁H₂₆O₂

Color and Shape: Powder

Molecular weight: 310.19328

Ref: 45-1394008

Mestranol

CAS: 72-33-3

Mestranol

Formula: C₂₁H₂₆O₂

Purity: 99%

Molecular weight: 310.43

Ref: 54-BUP14919

Mestranol

CAS: 72-33-3

Mestranol (Devocin), a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.

Formula: C₂₁H₂₆O₂

Purity: 99.16%

Color and Shape: Solid

Molecular weight: 310.4299

Ref: TM-T1579

Mestranol

CAS: 72-33-3

Mestranol

Formula: C₂₁H₂₆O₂

Purity: ≥98%

Molecular weight: 310.43

Ref: 54-OR1027921

17α-Ethynylestradiol-2,4,16,16-d4 3-Methyl Ether

CAS: 72-33-3

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 314.46

Ref: 3U-D6142

17α-Ethynylestradiol-16,16-d2 3-Methyl Ether

CAS: 72-33-3

Purity: 97 atom % D

Color and Shape: White Solid

Molecular weight: 312.45

Ref: 3U-D5990

Mestranol (Standard)

CAS: 72-33-3

Mestranol (Standard) is the standard substance of Mestranol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Mestranol (Devocin), a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.

Formula: C₂₁H₂₆O₂

Molecular weight: 310.4299

Ref: TM-TMSM-1575

Mestranol

Controlled Product

CAS: 72-33-3

Formula: C₂₁H₂₆O₂

Color and Shape: Off-White To Beige

Molecular weight: 310.43

Ref: 04-C14915000

Mestranol

Controlled Product

CAS: 72-33-3

Formula: C₂₁H₂₆O₂

Color and Shape: Neat

Molecular weight: 310.43

Ref: 86-MM1698.00

Mestranol

CAS: 72-33-3

Formula: C₂₁H₂₆O₂

Color and Shape: Off-White To Beige

Molecular weight: 310.43

Ref: 61-FOR1698.00

Mestranol

Controlled Product

CAS: 72-33-3

Formula: C₂₁H₂₆O₂

Color and Shape: Neat

Molecular weight: 310.43

Ref: TR-M258755

Mestranol RS

CAS: 72-33-3

Color and Shape: White To Pale Yellowish White Solid Crystalline Powder

Ref: 2K-116000002

Mestranol

CAS: 72-33-3

Mestranol is a synthetic estrogen, which is derived from chemical synthesis. Its mode of action involves being a prodrug of ethinylestradiol, meaning it is metabolized in the liver to its active form, which then binds to estrogen receptors in target tissues. This binding alters the expression of genes, influencing the reproductive system to prevent ovulation. By inhibiting the release of gonadotropins (LH and FSH) from the pituitary, it effectively halts the maturation of ovarian follicles.

Formula: C₂₁H₂₆O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 310.43 g/mol

Ref: 3D-FM25119

Mestranol

CAS: 72-33-3

Formula: C₂₁H₂₆O₂

Color and Shape: Solid

Molecular weight: 310.4

Ref: BE-BePure-23913

17α-Ethynylestradiol-16,16-d2 3-Methyl Ether

CAS: 72-33-3

Formula: C₂₁H₂₆O₂

Color and Shape: Solid

Molecular weight: 310.4

Ref: BE-MD-2604D2

17alpha-Ethynylestradiol-2,4,16,16-[d4] 3-Methyl Ether

CAS: 72-33-3

Formula: C₂₁H₂₆O₂

Color and Shape: Solid

Molecular weight: 310.4

Ref: BE-MD-2604D4

MESTRANOL

CAS: 72-33-3

Purity: 99%

Molecular weight: 310.4370117

Ref: 10-F825634

17Alpha-Ethynylestradiol-2,4,16,16-d4 3-Methyl Ether

Controlled Product

CAS: 72-33-3

Applications 17alpha-Ethynylestradiol-2,4,16,16-d4 3-Methyl Ether is a useful isotopically labeled compound of Mestranol (M258755)

Formula: C₂₁D₄H₂₂O₂

Color and Shape: Neat

Molecular weight: 314.4546

Ref: TR-M258757

17Alpha-Ethynylestradiol-16,16-d2 3-Methyl Ether

Controlled Product

CAS: 72-33-3

Applications 17alpha-Ethynylestradiol-16,16-d2 3-Methyl Ether is a useful isotopically labeled compound of Mestranol (M258755)

Formula: C₂₁D₂H₂₄O₂

Color and Shape: Neat

Molecular weight: 312.4423

Ref: TR-M258756