CAS 72496-41-4

Pirarubicin

Description:

Pirarubicin, with the CAS number 72496-41-4, is an anthracycline antibiotic that is primarily used as an antineoplastic agent in cancer therapy. It is structurally related to doxorubicin and exhibits similar mechanisms of action, primarily by intercalating into DNA, thereby inhibiting DNA and RNA synthesis, which leads to cell death. Pirarubicin is particularly effective against various types of cancers, including breast cancer and leukemia. Its pharmacological profile includes a moderate to high level of cytotoxicity, and it is often administered intravenously. The drug is known for its potential side effects, which may include cardiotoxicity, myelosuppression, and gastrointestinal disturbances. Due to its chemical structure, Pirarubicin can also generate reactive oxygen species, contributing to its anticancer effects. The compound is typically used in combination with other chemotherapeutic agents to enhance therapeutic efficacy while managing resistance. As with all chemotherapeutic agents, careful monitoring of patients is essential to mitigate adverse effects and optimize treatment outcomes.

Formula:C₃₂H₃₇NO₁₂

InChI:InChI=1/C32H37NO12/c1-14-31(45-21-8-3-4-9-42-21)17(33)10-22(43-14)44-19-12-32(40,20(35)13-34)11-16-24(19)30(39)26-25(28(16)37)27(36)15-6-5-7-18(41-2)23(15)29(26)38/h5-7,14,17,19,21-22,31,34,37,39-40H,3-4,8-13,33H2,1-2H3/t14-,17-,19?,21+,22-,31+,32-/m0/s1

InChI key:InChIKey=KMSKQZKKOZQFFG-YXRRJAAWSA-N

SMILES:O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4OC)C[C@](C(CO)=O)(O)C1)[C@H]5C[C@H](N)[C@H](O[C@@H]6CCCCO6)[C@H](C)O5

Synonyms:

(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-[(2S)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside
(2''R)-4'-O-Tetrahydropyranyladriamycin
(2′′R)-4′-O-Tetrahydropyranyladriamycin
(2′′R)-4′-O-Tetrahydropyranyldoxorubicin
(3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside
(8S,10S)-10-((3-Amino-2,3,6-trideoxy-4-O-(2R-tetrahydro-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
1609Rb
4'-O-Tetrahydropyranyladriamycin
4'-O-Tetrahydropyranyldoxorubicin
5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, [8S-[8α,10α(S*)]]-
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
Pinorubicin
Pirarubicin Hydrochloride
Pirarubicin [INN:JAN]
Pirarubicina
Pirarubicina [Spanish]
Pirarubicine
Pirarubicine [French]
Pirarubicinum
Pirarubicinum [Latin]
THP-adriamycin
Therarubicin
(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, [8S-[8α,10α(S*)]]-
(8S)-10α-[[3-Amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
l)-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hy
(7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-4-o-(tetrahydro-2h-pyran-2-y
(8s-cis)-droxyacetyl)-1-methoxy
(8S)-10-[(2S,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
5,12-Naphthacenedione, 10-3-amino-2,3,6-trideoxy-4-O-(2R)-tetrahydro-2H-pyran-2-yl-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
THP-ADM
Pirarubicin(THP-AdriaMycin)
THEPRUBICIN
Therarubiein
Pirarubicin(BICINS)
Pirabucin
PIRARUBICIN
(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
(8S,10S)-10α-[[3-Amino-4-O-(tetrahydro-2H-pyran-2-yl)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-hydroxyacetyl-1-methoxy-5,12-naphthacenedione
See more synonyms

Found 9 products.

+ Info
Pirarubicin
CAS:
- 72496-41-4
Pirarubicin
Formula:C₃₂H₃₇NO₁₂
Purity:98%
Molecular weight:627.64
Ref: 54-OR1023344
1mg
37.00€
VAT not included
5mg
55.00€
VAT not included
10mg
80.00€
VAT not included
50mg
278.00€
VAT not included
100mg
433.00€
VAT not included
250mg
988.00€
VAT not included
+ Info
Pirarubicin
CAS:
- 72496-41-4
Pirarubicin
Formula:C₃₂H₃₇NO₁₂
Purity:≥95%
Molecular weight:627.64
Ref: 54-BUP10616
5mg
51.00€
VAT not included
10mg
83.00€
VAT not included
25mg
163.00€
VAT not included
50mg
273.00€
VAT not included
100mg
463.00€
VAT not included
+ Info
(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
CAS:
- 72496-41-4
Formula:C₃₂H₃₇NO₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:627.6357
Ref: IN-DA0065SG
1mg
56.00€
VAT not included
5mg
84.00€
VAT not included
10mg
123.00€
VAT not included
50mg
312.00€
VAT not included
100mg
633.00€
VAT not included
250mg
938.00€
VAT not included
+ Info
Pirarubicin
CAS:
- 72496-41-4
Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.
Formula:C₃₂H₃₇NO₁₂
Purity:97.80% - 99.15%
Color and Shape:Solid
Molecular weight:627.6357
Ref: TM-T6628
+ Info
Pirarubicin
CAS:
- 72496-41-4
Formula:C₃₂H₃₇NO₁₂
Purity:≥ 95%
Color and Shape:Red to orange powder
Molecular weight:627.64
Ref: 7W-GA1643
10mg
134.00€
VAT not included
25mg
306.00€
VAT not included
+ Info
Pirarubicin
CAS:
- 72496-41-4
Antibiotic of anthracycline class; DNA synthesis inhibitor
Formula:C₃₂H₃₇NO₁₂
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:627.64 g/mol
Ref: 3D-FP27079
50mg
502.00€
VAT not included
100mg
721.00€
VAT not included
250mg
1,190.00€
VAT not included
500mg
1,696.00€
VAT not included
+ Info
Pirarubicin
CAS:
- 72496-41-4
(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-6-methyl-5-(((R)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
Formula:C₃₂H₃₇NO₁₂
Purity:98%
Molecular weight:627.64
Ref: IN-DG148292
+ Info
Pirarubicin
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 72496-41-4
Applications Structural analog of Doxorubicin. Antineoplastic.
References Umezawa, H., et al.: J. Antibiot., 32, 1082 (1979), Majima, H., et al.: Biomed. Pharmacother., 41, 237 (1987), Miller, A.A., et al.: Cancer Res., 47, 1461 (1987), Fallik, D., et al.: Ann. Ocol., 14, 856 (2003),
Formula:C₃₂H₃₇NO₁₂
Color and Shape:Neat
Molecular weight:627.64
Ref: TR-P501500
5mg
166.00€
VAT not included
10mg
196.00€
VAT not included
50mg
664.00€
VAT not included
+ Info
Pirarubicin
CAS:
- 72496-41-4
Formula:C₃₂H₃₇NO₁₂
Molecular weight:627.64
Ref: ST-EA-CP-P178000
10mg
To inquire
25mg
To inquire
50mg
To inquire
100mg
To inquire

CAS 72496-41-4

Pirarubicin

Pirarubicin

Ref: 54-OR1023344

Pirarubicin

Ref: 54-BUP10616

(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

Ref: IN-DA0065SG

Pirarubicin

Ref: TM-T6628

Pirarubicin

Ref: 7W-GA1643

Pirarubicin

Ref: 3D-FP27079

Pirarubicin

Ref: IN-DG148292

Pirarubicin

Ref: TR-P501500

Pirarubicin

Ref: ST-EA-CP-P178000