CAS 72509-76-3
:Felodipine
Description:
Felodipine is a dihydropyridine calcium channel blocker primarily used in the treatment of hypertension and angina pectoris. It functions by selectively inhibiting calcium ions from entering vascular smooth muscle and cardiac muscle during depolarization, leading to vasodilation and reduced blood pressure. Felodipine is characterized by its lipophilic nature, which enhances its absorption and bioavailability. The compound typically appears as a yellow crystalline solid and has a relatively long half-life, allowing for once-daily dosing. Its pharmacokinetics are influenced by factors such as food intake, which can affect its absorption. Felodipine is metabolized in the liver, primarily by cytochrome P450 enzymes, and its metabolites are excreted mainly through urine. Common side effects may include peripheral edema, headache, and flushing. Due to its mechanism of action, felodipine is effective in managing cardiovascular conditions, but it should be used with caution in patients with certain pre-existing conditions or those taking specific medications that may interact with its metabolism.
Formula:C18H19Cl2NO4
InChI:InChI=1/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
InChI key:InChIKey=RZTAMFZIAATZDJ-UHFFFAOYSA-N
SMILES:C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=C(Cl)C(Cl)=CC=C2
Synonyms:- H 154/82
- Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- Felodipine
- Plendil
- 4-(2,3-dichlorophenyl)-1,4-dihyro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester
- 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester
- 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester
- 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester
- ,ethylmethylester
- Felodipin
- Agon
- 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid, Methyl Ester, Feloday, Flodil,
- FelodipineUsp25DmfGmp
- dl-Felodipine
- h154/82
- Hydac
- (RS)-Felodipine
- Splendil
- modip
- ethylmethyl4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica
- FEXOFENADINE HCL
- See more synonyms
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Found 25 products.
Felodipine
CAS:Formula:C18H19Cl2NO4Purity:>98.0%(HPLC)(N)Color and Shape:White to Light orange to Pale yellow green powder to crystalMolecular weight:384.25Felodipine
CAS:<p>A dihydropyridine calcium channel blocker</p>Formula:C18H19Cl2NO4Color and Shape:Powder or crystals or crystalline powder, Yellow to yellow-greenMolecular weight:384.25Felodipine
CAS:FelodipineFormula:C18H19Cl2NO4Purity:99.8%Color and Shape:Off WhiteMolecular weight:383.06911Felodipine
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C18H19Cl2NO4Color and Shape:White Yellow PowderMolecular weight:383.06911Felodipine
CAS:<p>Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.</p>Formula:C18H19Cl2NO4Purity:99.91%Color and Shape:SolidMolecular weight:384.253-Ethyl 5-Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate
CAS:<p>3-Ethyl 5-Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate</p>Purity:99%Molecular weight:384.25g/molFelodipine
CAS:Formula:C18H19Cl2NO4Purity:≥ 98.0% (dried basis)Color and Shape:White or light-yellow crystalline powderMolecular weight:384.25Felodipine-d3 (2,3-dichlorophenyl-d3)
CAS:Purity:99 atom % DColor and Shape:Yellow SolidMolecular weight:387.28Felodipine 100 µg/mL in Acetonitrile
CAS:Formula:C18H19Cl2NO4Color and Shape:Single SolutionMolecular weight:384.25Felodipine
CAS:<p>Applications A dihydropyridine calcium channel blocker.<br>References Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981), Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002), O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006),<br></p>Formula:C18H19Cl2NO4Color and Shape:Off WhiteMolecular weight:384.25Felodipine-13C4, d3
CAS:Controlled Product<p>Applications Felodipine-13C4, d3 is the labeled analogue of Felodipine (F232375), a dihydropyridine calcium channel blocker.<br>References Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981); Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002); O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005); Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006)<br></p>Formula:C1413C4H16D3Cl2NO4Color and Shape:NeatMolecular weight:391.24Felodipine - Bio-X ™
CAS:<p>Felodipine is a calcium channel blocker and a member of the 1,4-dihydropyridine class of calcium channel blockers that is used to treat high blood pressure and related conditions. Felodipine increases the level of natriuretic peptide in the blood and reduces levels of infectious diseases such as influenza A virus and respiratory syncytial virus (RSV).<br>Felodipine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formula:C18H19Cl2NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:384.25 g/molFelodipine
CAS:<p>M06306 - Felodipine</p>Formula:C18H19Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:384.25rac Felodipine-13C4
CAS:Controlled ProductFormula:C4C14H19Cl2NO4Color and Shape:NeatMolecular weight:388.224Felodipine
CAS:<p>L-type calcium channel blocker; anti-hypertensive</p>Formula:C18H19Cl2NO4Purity:Min. 95%Color and Shape:White PowderMolecular weight:384.25 g/mol
