CAS 72571-82-5

Pipemidic acid trihydrate

Description:

Pipemidic acid trihydrate is a synthetic antimicrobial agent belonging to the class of quinolone derivatives, primarily used for its antibacterial properties, particularly against urinary tract infections. It is characterized by its chemical structure, which includes a pipemidic acid moiety that contributes to its pharmacological activity. The trihydrate form indicates that the compound contains three molecules of water per molecule of pipemidic acid, which can influence its solubility and stability. Typically, pipemidic acid exhibits moderate solubility in water, and its solubility can be affected by pH and temperature. The compound is known for its mechanism of action, which involves inhibiting bacterial DNA gyrase, thereby disrupting DNA replication in susceptible bacteria. In terms of safety, pipemidic acid trihydrate is generally well-tolerated, but like all medications, it may have side effects and contraindications that should be considered. Its use is often guided by susceptibility patterns of the target bacteria, making it important in clinical settings.

Formula: C₁₄H₁₇N₅O₃·3H₂O

InChI: InChI=1/C14H17N5O3.3H2O/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19;;;/h7-8,15H,2-6H2,1H3,(H,21,22);3*1H2

InChI key: InChIKey=URMXYPLWYMOYPG-UHFFFAOYSA-N

SMILES: C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CN=C(N2)N3CCNCC3.O

Synonyms:

• Pipemidic acid trihydrate
• Pyrido[2,3-D]Pyrimidine-6-Carboxylic Acid, 8-Ethyl-5,8-Dihydro-5-Oxo-2-(1-Piperazinyl)-, Hydrate (1:3)
• Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-, trihydrate
• 8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate
• PipeMidic Acid&nbsp
• Pipemidic Acid hydrate
• Pipemidic acid trihydrate CRS
• Pipemidic acid trihydrate USP/EP/BP

Pipemidic Acid Trihydrate

CAS: 72571-82-5

Color and Shape: Neat

Ref: 61-FOR0401.00

PIPEMIDIC ACID TRIHYDRATE CRS

CAS: 72571-82-5

PIPEMIDIC ACID TRIHYDRATE CRS

Formula: C₁₄H₁₇N₅O₃

Molecular weight: 303.3165

Ref: 41-Y0001476

Pipemidic Acid Trihydrate

CAS: 72571-82-5

Formula: C₁₄H₂₃N₅O₆

Purity: 99%

Color and Shape: Solid

Molecular weight: 357.3623

Ref: IN-DA003TSH

8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate

CAS: 72571-82-5

8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate

Purity: 99%

Molecular weight: 357.37g/mol

Ref: 54-OR1065387

8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate

CAS: 72571-82-5

8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate

Purity: 99%

Molecular weight: 357.36g/mol

Ref: 54-OR1044216

Pipemidic Acid Trihydrate

Controlled Product

CAS: 72571-82-5

Formula: C₁₄H₁₇N₅O₃H₂O

Color and Shape: Neat

Molecular weight: 357.36

Ref: 86-MM0401.00

Pipemidic Acid Trihydrate

Controlled Product

CAS: 72571-82-5

Applications An antibacterial agent that is effective againts garam negative bacteria such as Pseudomonas Aeruginosa as well as some gram positive bacteria.
References Massano, S. et al.: Antimicrob. Agents Chemother., 8, 132 (1975); Falagas, M.E. et al.: J. Antimicrob, Chemother., 65, 1863 (2010);

Formula: C₁₄H₁₇N₅O₃·3H₂O

Color and Shape: White To Off-White

Molecular weight: 357.36

Ref: TR-P479800

Pipemidic acid trihydrate

CAS: 72571-82-5

Pipemidic acid trihydrate is a compound of the pyrazole ring and the carboxylic acid group. It has been used as an antimicrobial agent in clinical studies for the treatment of inflammatory bowel disease. Pipemidic acid trihydrate is not absorbed by the gastrointestinal tract and must be administered orally. This drug also has anti-inflammatory properties, which may be due to its inhibition of cytokine production by mast cells and macrophages. Pipemidic acid trihydrate can be used to treat a range of neurological disorders, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, stroke, and other nervous system diseases.

Formula: C₁₄H₁₇N₅O₃·3H₂O

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 357.36 g/mol

Ref: 3D-FP59792