CAS 72571-82-5
:Pipemidic acid trihydrate
Description:
Pipemidic acid trihydrate is a synthetic antimicrobial agent belonging to the class of quinolone derivatives, primarily used for its antibacterial properties, particularly against urinary tract infections. It is characterized by its chemical structure, which includes a pipemidic acid moiety that contributes to its pharmacological activity. The trihydrate form indicates that the compound contains three molecules of water per molecule of pipemidic acid, which can influence its solubility and stability. Typically, pipemidic acid exhibits moderate solubility in water, and its solubility can be affected by pH and temperature. The compound is known for its mechanism of action, which involves inhibiting bacterial DNA gyrase, thereby disrupting DNA replication in susceptible bacteria. In terms of safety, pipemidic acid trihydrate is generally well-tolerated, but like all medications, it may have side effects and contraindications that should be considered. Its use is often guided by susceptibility patterns of the target bacteria, making it important in clinical settings.
Formula:C14H17N5O3·3H2O
InChI:InChI=1/C14H17N5O3.3H2O/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19;;;/h7-8,15H,2-6H2,1H3,(H,21,22);3*1H2
InChI key:InChIKey=URMXYPLWYMOYPG-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CN=C(N2)N3CCNCC3.O
Synonyms:- Pipemidic acid trihydrate
- Pyrido[2,3-D]Pyrimidine-6-Carboxylic Acid, 8-Ethyl-5,8-Dihydro-5-Oxo-2-(1-Piperazinyl)-, Hydrate (1:3)
- Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-, trihydrate
- 8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate
- PipeMidic Acid 
- Pipemidic Acid hydrate
- Pipemidic acid trihydrate CRS
- Pipemidic acid trihydrate USP/EP/BP
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Pipemidic Acid Trihydrate
CAS:Formula:C14H17N5O3·3H2OPurity:>98.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:357.37PIPEMIDIC ACID TRIHYDRATE CRS
CAS:PIPEMIDIC ACID TRIHYDRATE CRSFormula:C14H17N5O3Molecular weight:303.31658-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate
CAS:8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrateFormula:C14H23N5O6Purity:>99%Molecular weight:357.368-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate
CAS:8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrateFormula:C14H23N5O6Purity:99%Molecular weight:357.37Pipemidic Acid Trihydrate
CAS:Formula:C14H17N5O3·3H2OColor and Shape:White To Off-WhiteMolecular weight:357.36Pipemidic Acid Trihydrate
CAS:Controlled ProductFormula:C14H17N5O3·3H2OColor and Shape:NeatMolecular weight:357.368-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate
CAS:Formula:C14H23N5O6Purity:99%Color and Shape:SolidMolecular weight:357.3623Pipemidic Acid Trihydrate
CAS:Controlled ProductApplications An antibacterial agent that is effective againts garam negative bacteria such as Pseudomonas Aeruginosa as well as some gram positive bacteria.
References Massano, S. et al.: Antimicrob. Agents Chemother., 8, 132 (1975); Falagas, M.E. et al.: J. Antimicrob, Chemother., 65, 1863 (2010);Formula:C14H17N5O3·3H2OColor and Shape:NeatMolecular weight:357.36Pipemidic acid trihydrate
CAS:Pipemidic acid trihydrate is a compound of the pyrazole ring and the carboxylic acid group. It has been used as an antimicrobial agent in clinical studies for the treatment of inflammatory bowel disease. Pipemidic acid trihydrate is not absorbed by the gastrointestinal tract and must be administered orally. This drug also has anti-inflammatory properties, which may be due to its inhibition of cytokine production by mast cells and macrophages. Pipemidic acid trihydrate can be used to treat a range of neurological disorders, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, stroke, and other nervous system diseases.Formula:C14H17N5O3·3H2OPurity:Min. 95%Color and Shape:Off-White PowderMolecular weight:357.36 g/mol
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