CAS 72873-74-6

SKF-86002

Description:

SKF-86002, with the CAS number 72873-74-6, is a chemical compound that belongs to the class of selective serotonin reuptake inhibitors (SSRIs). It is primarily studied for its potential therapeutic effects in treating various mood disorders, including depression and anxiety. The compound exhibits a high affinity for serotonin transporters, which facilitates the increase of serotonin levels in the synaptic cleft, thereby enhancing mood and emotional well-being. SKF-86002 is characterized by its ability to selectively inhibit the reuptake of serotonin without significantly affecting other neurotransmitter systems, which contributes to its favorable side effect profile compared to non-selective antidepressants. Additionally, its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are crucial for determining its efficacy and safety in clinical applications. Research continues to explore its full therapeutic potential and mechanisms of action, as well as its interactions with other medications. Overall, SKF-86002 represents a significant area of interest in psychopharmacology.

Formula: C₁₆H₁₄Cl₂FN₃S

InChI: InChI=1/C16H12FN3S.2ClH/c17-13-3-1-11(2-4-13)14-15(12-5-7-18-8-6-12)20-9-10-21-16(20)19-14;;/h1-8H,9-10H2;2*1H

SMILES: c1cc(ccc1c1c(c2ccncc2)n2CCSc2n1)F.Cl.Cl

Synonyms:

• 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole
• Sk&F 86002
• Sk&F 86002-A(2)
• Imidazo(2,1-b)thiazole, 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-
• 6-(4-Fluorophenyl)-5-(Pyridin-4-Yl)-2,3-Dihydroimidazo[2,1-B][1,3]Thiazole
• 6-(4-Fluorophenyl)-5-Pyridin-4-Yl-2,3-Dihydroimidazo[2,1-B][1,3]Thiazole Dihydrochloride
• Skf 86002

Imidazo[2,1-b]thiazole,6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-

CAS: 72873-74-6

Formula: C₁₆H₁₂FN₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 297.3500

Ref: IN-DA005E7R

SKF-86002

CAS: 72873-74-6

Formula: C₁₆H₁₂N₃FS

Molecular weight: 297.35

Ref: 7W-GL9447

SKF-86002

CAS: 72873-74-6

SKF-86002

Formula: C₁₆H₁₂FN₃S

Purity: ≥98%

Molecular weight: 297.35

Ref: 54-BUP10580

SKF-86002

CAS: 72873-74-6

6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b]thiazole

Formula: C₁₆H₁₂FN₃S

Purity: 98%

Molecular weight: 297.35

Ref: IN-DG234144

SKF-86002

CAS: 72873-74-6

SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).

Formula: C₁₆H₁₂FN₃S

Purity: 98% - 99.85%

Color and Shape: Solid

Molecular weight: 297.35

Ref: TM-T2367

SKF-86002

CAS: 72873-74-6

SKF-86002

Formula: C₁₆H₁₂FN₃S

Purity: 98%

Molecular weight: 297.34998

Ref: 54-BISN0228

SKF 86002

Controlled Product

CAS: 72873-74-6

Formula: C₁₆H₁₂FN₃S

Color and Shape: Neat

Molecular weight: 297.35

Ref: TR-S550083