CAS 73069-13-3
:Atractylenolide I
Description:
Atractylenolide I is a natural compound primarily derived from the roots of the Atractylodes species, particularly Atractylodes macrocephala. It belongs to the class of sesquiterpenes and is known for its potential pharmacological properties. This compound typically exhibits a white to pale yellow crystalline appearance and has a characteristic aromatic odor. Atractylenolide I is recognized for its anti-inflammatory, antioxidant, and immunomodulatory effects, making it of interest in traditional medicine and modern pharmacology. Its mechanism of action may involve the modulation of various signaling pathways, contributing to its therapeutic potential. Additionally, Atractylenolide I has been studied for its effects on gastrointestinal health and its role in enhancing digestive functions. As with many natural compounds, further research is necessary to fully elucidate its biological activities and potential applications in medicine. Safety and efficacy assessments are crucial for any therapeutic use, and ongoing studies continue to explore its benefits and mechanisms.
Formula:C15H18O2
InChI:InChI=1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1
InChI key:InChIKey=ZTVSGQPHMUYCRS-SWLSCSKDSA-N
SMILES:C[C@]12[C@@](CC=3C(=C1)OC(=O)C3C)(C(=C)CCC2)[H]
Synonyms:- (4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,5,6,7,8,8a-hexahydronaphtho[2,3-b]furan-2(4H)-one
- (4aS,8aS)-4a,5,6,7,8,8a-Hexahydro-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one
- Naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a-hexahydro-3,8a-dimethyl-5-methylene-, (4aS,8aS)-
- Naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a-hexahydro-3,8a-dimethyl-5-methylene-, (4aS-trans)-
- atractylenolide I
- Atractylodes oil
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Atractylenolide I (Standard)
CAS:Atractylenolide I (Standard) is a reference standard for research and analysis in studies involving Atractylenolide I. 1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide-I significantly sensitizes the response of MyD88(+) EOC cells to paclitaxel by blocking MD-2-mediated TLR4/MyD88 signaling.Formula:C15H18O2Molecular weight:230.3022(4aS,8aS)-3,8a-Dimethyl-5-methylene-4a,5,6,7,8,8a-hexahydronaphtho[2,3-b]furan-2(4H)-one
CAS:Formula:C15H18O2Purity:99%Color and Shape:SolidMolecular weight:230.3022Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:White SolidMolecular weight:230.3022Atractylenolide I
CAS:LactoneFormula:C15H18O2Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:230.31Atractylenolide I
CAS:Atractylenolide I is a natural sesquiterpenoid lactone, which is isolated from the rhizomes of Atractylodes macrocephala, a traditional medicinal herb widely used in Asian medicine. Its mode of action involves modulation of various signaling pathways, notably anti-inflammatory and immunoregulatory mechanisms. It functions by inhibiting pro-inflammatory cytokines and oxidative stress markers, suggesting a potent role in managing inflammatory responses.
Formula:C15H18O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:230.3 g/mol
![(4aS,8aS)-3,8a-Dimethyl-5-methylene-4a,5,6,7,8,8a-hexahydronaphtho[2,3-b]furan-2(4H)-one](https://static.cymitquimica.com/products/IN/thumb/DA00FAFP.jpg)
