CAS 736048-65-0

Formula: C20H25F3N6O3

InChI: InChI=1S/C20H25F3N6O3/c21-20(22,23)32-17-4-2-1-3-15(17)11-26-19-27-12-16(29(30)31)18(28-19)25-10-14-7-5-13(9-24)6-8-14/h1-4,12-14H,5-11,24H2,(H2,25,26,27,28)

InChI key: HKOWATVSFKRXRW-UHFFFAOYSA-N

SMILES: C1CC(CCC1CN)CNC2=NC(=NC=C2[N+](=O)[O-])NCC3=CC=CC=C3OC(F)(F)F

PKC-θ inhibitor

CAS: 736048-65-0

PKC-θ inhibitor

Molecular weight: 454.45g/mol

Ref: 54-BUP08969

PKC-θ inhibitor

CAS: 736048-65-0

Formula: C₂₀H₂₅F₃N₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 454.4461

Ref: IN-DA01EO64

PKC-θ inhibitor

CAS: 736048-65-0

PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.

Formula: C₂₀H₂₅F₃N₆O₃

Purity: 99.46%

Color and Shape: Solid

Molecular weight: 454.4461

Ref: TM-T5423

PKC-θ inhibitor

CAS: 736048-65-0

Formula: C₂₀H₂₅F₃N₆O₃

Molecular weight: 454.45

Ref: 4Z-K-031051

PKC-theta inhibitor

CAS: 736048-65-0

Formula: C₂₀H₂₅F₃N₆O₃

Molecular weight: 454.4

Ref: BE-RMCK020051

N4-((4-(Aminomethyl)cyclohexyl)methyl)-5-nitro-N2-(2-(trifluoromethoxy)benzyl)pyrimidine-2,4-diamine

CAS: 736048-65-0

Formula: C₂₀H₂₅F₃N₆O₃

Purity: 99%

Molecular weight: 454.45

Ref: IN-DG01124069

PKC-θ Inhibitor 2

CAS: 736048-65-0

Purity: 98%

Molecular weight: 454.194

Ref: 10-F799530

PKC-theta inhibitor

CAS: 736048-65-0

PKC-theta inhibitors are a class of compounds that inhibit protein kinase C-theta (PKC-θ), which is a serine/threonine-specific protein kinase. PKC-θ inhibition is being studied as a potential therapeutic strategy for the treatment of Alzheimer's disease and HIV integrase inhibitor. A number of strategies have been developed to inhibit the enzyme, including paraformaldehyde, nucleophilic substitutions, primary amines, and alkylation. These strategies have yielded different yields and chemotypes with varying bioactivity profiles.

Formula: C₂₀H₂₅F₃N₆O₃

Purity: Min. 95%

Molecular weight: 454.45 g/mol

Ref: 3D-LEB04865