CAS 7369-91-7
:H-Pro-pNA
Description:
H-Pro-pNA, also known as L-Proline p-nitroanilide, is a chemical compound that serves primarily as a substrate in enzymatic assays, particularly for the detection of prolyl endopeptidases. It is characterized by its structure, which includes a proline amino acid linked to a p-nitroaniline moiety. This compound is typically a white to off-white crystalline solid and is soluble in polar solvents such as water and methanol. H-Pro-pNA is often used in biochemical research due to its ability to release p-nitroaniline upon enzymatic cleavage, which can be quantitatively measured, making it useful for studying enzyme kinetics and activity. The compound's stability and reactivity under physiological conditions make it a valuable tool in the field of biochemistry. Safety precautions should be taken when handling H-Pro-pNA, as with many chemical substances, to avoid potential health hazards associated with exposure.
Formula:C11H13N3O3
InChI:InChI=1/C11H13N3O3/c15-11(10-2-1-7-12-10)13-8-3-5-9(6-4-8)14(16)17/h3-6,10,12H,1-2,7H2,(H,13,15)/t10-/m0/s1
InChI key:JWXPYNYNEUYKOW-JTQLQIEISA-N
SMILES:C1C[C@@H](C(=O)Nc2ccc(cc2)N(=O)=O)NC1
Synonyms:- N-(4-nitrophenyl)-L-prolinamide
- H-Pro-Pna Hbr
- H-Pro-pNA・HCl
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