CAS 73731-37-0
:fmoc-L-threonine monohydrate
Description:
Fmoc-L-threonine monohydrate is a derivative of the amino acid threonine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is typically used in peptide synthesis, particularly in solid-phase peptide synthesis, due to its ability to protect the amino group of threonine while allowing for further reactions. The monohydrate form indicates that the compound contains one molecule of water per molecule of Fmoc-L-threonine, which can influence its solubility and stability. Fmoc-L-threonine itself is a polar, hydrophilic amino acid, contributing to the overall properties of the compound. It is generally soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), while being less soluble in water. The presence of the Fmoc group provides a convenient means for deprotection under mild basic conditions, facilitating the synthesis of peptides with specific sequences. Overall, Fmoc-L-threonine monohydrate is a valuable reagent in the field of organic chemistry and biochemistry for the construction of peptides.
Formula:C19H19NO5
InChI:InChI=1/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/t11-,17+/m1/s1
Synonyms:- Fmoc-Thr-OH monohydrate
- Fmoc-L-Threonine-OH
- Fmoc-L-Thr-OH
- N-[(9H-Fluoren-9ylmethoxy)carbonyl]-L-threonine
- N-[(9H-fluoren-9-ylmethoxy)carbonyl]threonine
- (2S,3S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-hydroxybutanoate
- N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-allothreonine
- Fmoc-Thr-OH.H2O
- Fmoc-L-threonine
- Fmoc-Thr-OH
- 2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Hydroxy-Butanoic Acid
- N-FMOC-L-THREONINE
- FMOC-L-THREONINE extrapure
- N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-THREONINE MONOHYDRATE
- N-FMOC-L-THREONINE MONOHYDRATE
- FMOC-L-THR-OH H2O
- N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-THREONINE
- FMOC-THR
- FMOC-L-THREONINE MONOHYDRATE
- FMOC-THREONINE
- N-ALPHA-FMOC-L-THREONINE
- N-(9-FLUORENYLMETHOXYCARBONYL)-L-THREONINE
- See more synonyms
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Found 8 products.
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-threonine Monohydrate
CAS:Formula:C19H19NO5·H2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:359.38Fmoc-Thr-OH
CAS:Educt for the synthesis of O-glycosylated threonine building blocks. Liu et al. described the synthesis of O-mannosylated Fmoc-Thr.Formula:C19H19NO5Purity:99.78%Color and Shape:White PowderMolecular weight:341.36Fmoc-Thr-OH
CAS:<p>M03388 - Fmoc-Thr-OH</p>Formula:C19H19NO5Purity:95%Color and Shape:White to very pale yellow crystal powderMolecular weight:341.363Fmoc-Thr-OH
CAS:<p>Fmoc-Thr-OH is a synthetic amino acid that has been used in the synthesis of peptides and glycopeptides. It is also a good building block for the construction of sialic acid derivatives. The Fmoc group can be removed by treating the compound with trifluoroacetic acid (TFA), which yields an unprotected l-threonine residue. This is then reacted with a benzyl ester to form an amide bond, forming an Fmoc-protected lactam. The chloride group on the benzyl ester can then be displaced by a reactive electrophile, such as trifluoroacetic acid (TFA) or N-hydroxysuccinimide, to form the desired product.<br>The analytical hplc method for quantifying Fmoc-Thr-OH uses choline as an internal standard and detects peaks at Rt = 1.80 min. The molecular weight of F</p>Formula:C19H19NO5Purity:Min. 95%Color and Shape:PowderMolecular weight:341.36 g/molFMOC-L-Threonine extrapure, 99%
CAS:Formula:C19H19NO5Purity:min. 99%Color and Shape:White, Crystalline powderMolecular weight:341.40
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