CAS 74-55-5

(+)-Ethambutol

Description:

(+)-Ethambutol, with the CAS number 74-55-5, is a synthetic organic compound primarily used as an antitubercular agent in the treatment of tuberculosis. It is a chiral molecule, existing in two enantiomeric forms, with the (+) form being the therapeutically active one. Ethambutol is characterized by its ability to inhibit the synthesis of the mycobacterial cell wall, specifically targeting the arabinogalactan component, which is crucial for the integrity of the bacterial cell wall. This mechanism of action makes it effective against Mycobacterium tuberculosis. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Ethambutol is known for its relatively low toxicity, although it can cause side effects such as optic neuritis and visual disturbances, necessitating regular monitoring of patients. It is often used in combination with other antitubercular drugs to enhance efficacy and prevent the development of drug resistance. The compound is a white to off-white crystalline powder, soluble in water, and has a melting point that reflects its stability under standard conditions.

Formula: C₁₀H₂₄N₂O₂

InChI: InChI=1/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m1/s1

InChI key: InChIKey=AEUTYOVWOVBAKS-UWVGGRQHSA-N

SMILES: [C@H](NCCN[C@@H](CC)CO)(CC)CO

Synonyms:

• (+)-2,2-Ethylenediiminodibutan-1-Ol
• (+)-N,N'-Bis[1-(hydroxymethyl)propyl]ethylenediamine
• (+)-S,S-Ethambutol
• (2R,2'R)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol
• (2S,2′S)-2,2′-(1,2-Ethanediyldiimino)bis[1-butanol]
• (2S,7S)-2,7-Diethyl-3,6-diazaoctane-1,8-diol
• 1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, (2S,2'S)-
• 1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, [S-(R*,R*)]-
• 1-Butanol, 2,2'-(ethylenediimino)di-, (+)-
• 1-Butanol, 2,2′-(1,2-ethanediyldiimino)bis-, (2S,2′S)-
• 2,2'-(Ethane-1,2-Diyldiimino)Dibutan-1-Ol
• Diambutol
• EMB
• Etambutol
• Purderal
• d-2,2'-(Ethylenediimino)bis(1-butanol)
• d-2,2'-(Ethylenediimino)di-1-butanol
• d-Ethambutol
• d-N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine
• Ethambutol
• Anti-EMB antibody produced in rabbit
• 2,2(1,2-Ethanediyldiimino)-bis-1-butanol
• Anti-Embigin precursor
• ETHAMBUTOL FREE BASE
• 2'-(1,2-ethanediyldiimino)bis-(r)-1-butanol
• Ethambutol USP/EP/BP
• Ethambutol HCL BP98,CP2000
• MGC71745
• Methyl phenylethynyl ketone
• 2’-(1,2-ethanediyldiimino)bis-(r)-1-butano
• 2,2'-(1,2-Ethanediyldiimino)bis[(2S)-1-butanol]
• (r)-2,2’-(1,2-ethanediyldiimino)bis-1-butanol
• 4-Phenyl-3-butyne-2-one
• Phenylethynyl methyl ketone
• 2’-(ethylenediimino)di-(+)-1-butano
• (+)- (R,R)-NN'-Ethylene bis(2-aMinobutan-1-ol)
• (3-Oxo-1-butynyl)benzene
• tibutol
• (+)-2,2-(Ethylenediimino)di-1-butanol
• 2,2’-(1,2-ethanediyldiimino)bis-,(r-(r*,r*))-1-butano
• Acetylphenylacetylene
• C06984
• (2S,2'S)-2,2'-(Ethane-1,2-diylbis(azanediyl))bis(butan-1-ol)
• Ethambutol BP98
• (+)-2,2’-(ethylenediimino)di-1-butanol
• Ethambutol (base and/or unspecified salts)
• ETHAMBUTOL HCL, USP STANDARD

Ethambutol Dihydrochloride

CAS: 1070-11-7, 74-55-5

Formula: C₁₀H₂₄N₂O₂·2HCl

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 277.23

Ref: 3B-E1011

1-Butanol,2,2'-(1,2-ethanediyldiimino)bis-, (2S,2'S)-

CAS: 74-55-5

Formula: C₁₀H₂₄N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.3098

Ref: IN-DA005JDC

Ethambutol

CAS: 74-55-5

Ethambutol

Purity: ≥98%

Molecular weight: 204.31g/mol

Ref: 54-BUP20886

Ethambutol

CAS: 74-55-5

Ethambutol (Myambutol) is an orally available anti-tuberculosis drug, arabinogalactan,modeling for hyperuricemia and optic neuropathy.

Formula: C₁₀H₂₄N₂O₂

Purity: 99.92%

Color and Shape: Crystals Solid

Molecular weight: 204.31

Ref: TM-T7062

Ethambutol

CAS: 74-55-5

Ethambutol is an antimicrobial compound, specifically an antitubercular agent, which is a synthetic derivative of ethylenediamine. It is classified as a bacteriostatic agent that primarily targets Mycobacterium tuberculosis. The mode of action of Ethambutol involves the inhibition of arabinosyl transferases, enzymes essential for the polymerization of arabinogalactan, a critical component of the mycobacterial cell wall. By disrupting cell wall biosynthesis, Ethambutol effectively hampers the growth and proliferation of the bacteria.

Formula: C₁₀H₂₄N₂O₂

Purity: Min. 95%

Molecular weight: 204.31 g/mol

Ref: 3D-AE64826

(2S,2’S)-2,2′-(Ethane-1,2-diylbis(azanediyl))bis(butan-1-ol)

CAS: 74-55-5

Formula: C₁₀H₂₄N₂O₂

Purity: 95.0%

Molecular weight: 204.314

Ref: 10-F329612