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CAS 74050-20-7

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Hydrocortisone Aceponate

Description:
Hydrocortisone aceponate is a synthetic corticosteroid used primarily for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various skin conditions, such as eczema and psoriasis. The compound is a derivative of hydrocortisone, modified to enhance its potency and reduce systemic side effects. Hydrocortisone aceponate is typically formulated as a topical preparation, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves the inhibition of pro-inflammatory cytokines and the suppression of immune responses, which helps to control inflammation and promote healing. The substance is generally well-tolerated, but like all corticosteroids, it may have potential side effects, particularly with prolonged use. It is important to follow medical guidance when using hydrocortisone aceponate to ensure effective and safe treatment.
Formula:C26H36O7
InChI:InChI=1/C26H36O7/c1-5-22(31)33-26(21(30)14-32-15(2)27)11-9-19-18-7-6-16-12-17(28)8-10-24(16,3)23(18)20(29)13-25(19,26)4/h12,18-20,23,29H,5-11,13-14H2,1-4H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1
InChI key:InChIKey=MFBMYAOAMQLLPK-FZNHGJLXSA-N
SMILES:C(COC(C)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])[H]
Synonyms:
  • (11Beta)-21-(Acetyloxy)-11-Hydroxy-3,20-Dioxopregn-4-En-17-Yl Propanoate
  • (11β)-21-(Acetyloxy)-11-hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
  • 11beta,17,21-Trihydroxy pregn-4-ene-3,20-dione 21-acetate 17-propionate
  • Aceponate d'hydrocortisone
  • Aceponate d'hydrocortisone [French]
  • Aceponato de hidrocortisona
  • Aceponato de hidrocortisona [Spanish]
  • Cortacare
  • Cortavance
  • Cortisol 17-propionate 21-acetate
  • See more synonyms
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