CAS 7414-83-7

Etidronate disodium

Description:

Etidronate disodium, with the CAS number 7414-83-7, is a bisphosphonate compound primarily used in the treatment of bone disorders, such as Paget's disease and osteoporosis. It functions by inhibiting bone resorption, thereby helping to maintain bone density. The substance is characterized by its disodium salt form, which enhances its solubility in water, making it suitable for intravenous administration. Chemically, etidronate contains a phosphonate group, which is responsible for its affinity to bone mineral. It is typically administered in a cyclic manner to maximize its therapeutic effects while minimizing potential side effects. The compound is generally well-tolerated, although it may cause gastrointestinal disturbances in some patients. In addition to its medical applications, etidronate disodium is also utilized in research settings to study bone metabolism and the effects of bisphosphonates on mineralization processes. Overall, etidronate disodium is a significant agent in the management of various bone-related conditions, contributing to improved patient outcomes in bone health.

Formula: C₂H₆Na₂O₇P₂

InChI: InChI=1/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-4

InChI key: InChIKey=FCBYKAIUKRZZGW-UHFFFAOYSA-N

SMILES: C(P(=O)(O)O)(P(=O)(O)O)(C)O.[Na]

Synonyms:

• (1-Hydroxyethane-1,1-Diyl)Di-Phosphonic Aci Disodium Salt
• (1-Hydroxyethylidene)Bis-Phosphonic Aci Disodium Salt
• (1-Hydroxyethylidene)Diphosphonic Acid, Disodium Salt
• (1-Hydroxyethylidene)bisphosphonic acid disodium salt
• 1-Hydroxyethane-1,1-Diyl)Diphosphonic Acid Disodium Salt
• 1-Hydroxyethane-1,1-diphosphonic acid disodium salt
• 1-Hydroxyethylidene)Di-Phosphonic Aci Disodium Salt
• 1-Hydroxyethylidene-1,1-Diphosphonic Acid Disodium Salt
• 1-Hydroxyethylidene-Bis-Phosphonic Acid, Disodium Salt
• Ba 49280E
• Bis(1-Hydroxyethylidene)Phosphonate, Disodium
• Calcimux
• Chelest PH 210
• Chelest PH 212
• Cublen K 2012
• Didronel
• Didronel R
• Dihidrogeno(1-Hidroxietiliden)Bisfosfonato De Disodio
• Dihydrogeno(1-Hydroxyethylidene)Bisphosphonate De Disodium
• Dihydrogeno(1-hydroxyethylidene)diphosphonate de disodium
• Dinatriumdihydrogen(1-hydroxyethyliden)bisphosphonat
• Disodium (1-Hydroxyethylidene)Diphosphonate
• Disodium (1-Oh-Ethylidene)Bisphosphonate
• Disodium (1-hydroxyethylidene)-1,1-bisphosphonate
• Disodium (1-hydroxyethylidene)-1,1-diphosphonate
• Disodium 1-Hydroxyethylidene Phosphonate
• Disodium 1-hydroxy-1,1-ethanediphosphonate
• Disodium 1-hydroxyethane-1-diphosphonate
• Disodium 1-hydroxyethanediphosphonate
• Disodium 1-hydroxyethylidenediphosphonate
• Disodium Dihydrogen (1-Hydroxyethylidene)Bisphosphonate
• Disodium Dihydrogen (1-Hydroxyethylidene)Diphosphonate
• Disodium Ethanol-1,1-Diphosphonate
• Disodium Etidronate
• Disodium HEDP
• Disodium ethane-1-hydroxy-1,1-diphosphonate
• Disodium ethane-1-hydroxy-1,1-diphosphonic acid
• Disodium ethane-1-hydroxy-1-diphosphonate
• Disodium hydroxy-[1-hydroxy-1-(hydroxy-oxidophosphoryl)ethyl]phosphinate
• Disodium hydroxyethylidene diphosphonate
• Disodium of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid
• Disodium salt of 1-Hydroxy Ethylidene-1,1-DiphosphonicAcid
• Ethane-1-Hydroxy-1,1-Diphosphonic Acid, Disodium Salt
• Etidron
• Etidronate
• Etidronate Disodium
• Etidronate Sodium
• Etidronic Acid Disodium Salt
• Fostex NZ 2
• HEDP・Na2
• Hedp Disodium Salt
• Hydroxyethylidene diphosphonic acid disodium salt
• Ostedron
• Ph 212
• Phosphonic acid, (1-hydroxyethylidene)bis-,
• Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt
• Phosphonic acid, (1-hydroxyethylidene)di-, disodium salt
• Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2)
• Sequion 10Na2
• Sm-5600
• Sodium Ethidronate
• Sodium Ethydronate
• Sodium Etidronate
• Sodium ethane-1-hydroxy-1,1-diphosphonate
• Sodiumetidronate
• TF 133B (chelating agent)
• Tf 133B
• Turpinal 2NZ
• Xydifon
• phosphonate, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2)
• Etidronate Disodium (200 mg)
• sodiumethidronate
• disodiumethydronate
• didronelr
• DIPHOSPHONICACID,(1-HYDROXYETHYLENE)-,DISODIUMSALT
• (1-hydroxyethylidene)diphosphonicacid,disodiumsalt
• P,P'-(1-Hydroxyethylidene)bisphosphonic Acid SodiuM Salt
• ETIDRONATE DISODIUM (1-HYDROXYETHYLIDONE-1,1-DIPHOSPHONIC ACID DISODIUM SALT)
• 1-Hydroxyethylidene-1,1-bis-(phosphonic acid) disodium salt
• sodiumethydronate
• (1-hydroxyethane-1,1-diyl)di-phosphonicacidisodiumsalt
• disodium hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate
• DisodiuM Etidronate Hydrate
• (1-HYDROXYETHYLIDENE)BISPHOSPHONIC ACID
• Phosphonicacid,(1-hydroxyethylidene)bis-,disodiumsalt
• disodiumdihydrogen(1-hydroxyethylidene)diphosphonate
• 1-Hydroxyethylidone-1,1-diphosphonicacidtrisodiumsalt
• 1-Hydroxyethylidone-1,1-diphosphonicacid
• etidronate disodium，ETD
• Pentasodiumetidronate
• disodium1-hydroxyethylidenephosphonate
• ETRIDRONIC ACID, DISODIUM SALT
• ETIDRONATE DISODIUM USP(CRM STANDARD)
• (1-hydroxyethylidene)di-phosphonicacidisodiumsalt
• 1-Hydroxyethylidone-1,1-diphosphonicaciddisodiumsalt
• (1-hydroxyethane-1,1-diyl)diphosphonicaciddisodiumsalt
• Etidronate disodiuM hydrate
• ethane-1-hydroxy-1,1-diphosphonicacid,disodiumsalt
• DisodiuM of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDPNa2)
• disodiumethanol-1,1-diphosphonate
• 1-Hydroxyethylidone-1,1-diphosphonicacidpentasodiumsalt
• ethydronate disodium
• (1-hydroxyethylidene)bis-phosphonicacidisodiumsalt
• Phosphonicacid, P,P'-(1-hydroxyethylidene)bis-, sodiuM salt (1:2)
• (1-HYDROXYETHYLIDENE)BISPHONIC ACID
• Disodium 1-Hydroxyethane-1,1-diphosphonate
• Dihydrogen (1-hydroxyethylidene)bisphosphonate disodium hydrate
• DIHYDROGEN (1-HYDROXYETHYLIDENE)BISPHOSPHONATE DISODIUM
• disodium hydroxy-[1-hydroxy-1-[hydroxy(oxidanidyl)phosphoryl]ethyl]phosphinate
• (1-Hydroxyethane-1,1-diyl)diphosphonic acid disodi

Disodium Etidronate Hydrate

CAS: 7414-83-7

Formula: C₂H₆Na₂O₇P₂·xH₂O

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 249.99 (as Anhydrous)

Ref: 3B-D4159

Etidronate disodium

CAS: 7414-83-7

A bisphosphonate bone resorption inhibitor

Formula: C₂H₆Na₂O₇P₂

Molecular weight: 249.99

Ref: 02-J62381

ETIDRONATE DISODIUM CRS

CAS: 7414-83-7

ETIDRONATE DISODIUM CRS

Formula: C₂H₆Na₂O₇P₂

Color and Shape: Added

Molecular weight: 249.9919

Ref: 41-Y0000572

Sodium etidronate

CAS: 7414-83-7

Sodium etidronate (Didronel), a bisphosphonate, resists degradation, inhibits osteoclasts, and may boost bone formation.

Formula: C₂H₆Na₂O₇P₂

Purity: 99.5% - 99.75%

Color and Shape: Liquid

Molecular weight: 249.99

Ref: TM-T1210

Disodium Etidronate Hydrate

CAS: 7414-83-7

Formula: C₂H₆Na₂O₇P₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 249.9919

Ref: IN-DA003PRC

Sodium etidronate

CAS: 7414-83-7

Sodium etidronate

Purity: ≥98%

Molecular weight: 249.99g/mol

Ref: 54-BUP15901

Etidronate disodium salt

CAS: 7414-83-7

Formula: C₂H₆Na₂O₇P₂·xH₂O

Purity: ≥ 98.0% (dried basis)

Color and Shape: White powder

Molecular weight: 249.99 (anhydrous)

Ref: 7W-GP3560

Etidronic Acid Disodium Salt

Controlled Product

CAS: 7414-83-7

Applications Etidronic acid is used as a calcium regulator. Etidronic acid is a bisphosphonate antiresorptive agent.
References Francis, M.D., et al.: Science, 165, 1264 (1969), Jowsey, J., et al.: J. Lab. Clin. Med. , 76, 126 (1970), Altman, R.D.: N. Engl. J. Med., 79, 583 (1985)

Formula: C₂H₆O₇P₂·2Na

Color and Shape: Light Yellow

Molecular weight: 249.99

Ref: TR-E935000

Etidronate disodium salt - Bio-X ™

CAS: 7414-83-7

Etidronate is a bisphosphate drug that is used to treat osteoporosis. It is an inhibitor of bone resorption and works by inhibiting the action of osteoclasts.

Formula: C₂H₈O₇P₂·2Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 249.99 g/mol

Ref: 3D-BE164429

Etidronate disodium

CAS: 7414-83-7

Atherosclerotic plaque inhibitor; anti-bone resorptive therapy

Formula: C₂H₆Na₂O₇P₂·xH₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 249.99 g/mol

Ref: 3D-FE35145

Etidronate Disodium (DISCONTINUED)

CAS: 7414-83-7

Other organo-phosphorous derivatives: salt of methylphosphonic acid and (aminoiminomethyl) urea (1:1)

Formula: C₂H₈O₇P₂·2Na

Color and Shape: White Powder

Molecular weight: 251.95407

Ref: 45-1268502