CAS 7414-83-7

Etidronate disodium

Description:

Agents in the first generation (e.g., etidronate disodium and tiludronate) that were dosed continuously produced poorly mineralized bone, because there was no interval for appropriate bone mineralization to occur. Subsequent studies that used a cyclic dosing schedule (400 mg/day for 2 weeks, followed by 2.5 months of calcium supplementation only) showed improvement in bone mineralization. Etidronate has been approved for treatment of Paget's disease of the bone but not for treatment of osteoporosis. Tiludronate is approximately 10-fold more potent than etidronate and, when given orally for 6 months (200, 400, or 800 mg/day), increases BMD by 2%. No further bone loss was detected in patients 6 months after cessation of therapy.

Formula: C₂H₆Na₂O₇P₂

InChI: InChI=1/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-4

InChI key: InChIKey=FCBYKAIUKRZZGW-UHFFFAOYSA-N

SMILES: C(P(=O)(O)O)(P(=O)(O)O)(C)O.[Na]

Synonyms:

• (1-Hydroxyethane-1,1-Diyl)Di-Phosphonic Aci Disodium Salt
• (1-Hydroxyethylidene)Bis-Phosphonic Aci Disodium Salt
• (1-Hydroxyethylidene)Diphosphonic Acid, Disodium Salt
• (1-Hydroxyethylidene)bisphosphonic acid disodium salt
• 1-Hydroxyethane-1,1-Diyl)Diphosphonic Acid Disodium Salt
• 1-Hydroxyethane-1,1-diphosphonic acid disodium salt
• 1-Hydroxyethylidene)Di-Phosphonic Aci Disodium Salt
• 1-Hydroxyethylidene-1,1-Diphosphonic Acid Disodium Salt
• 1-Hydroxyethylidene-Bis-Phosphonic Acid, Disodium Salt
• Ba 49280E
• Bis(1-Hydroxyethylidene)Phosphonate, Disodium
• Calcimux
• Chelest PH 210
• Chelest PH 212
• Cublen K 2012
• Didronel
• Didronel R
• Dihidrogeno(1-Hidroxietiliden)Bisfosfonato De Disodio
• Dihydrogeno(1-Hydroxyethylidene)Bisphosphonate De Disodium
• Dihydrogeno(1-hydroxyethylidene)diphosphonate de disodium
• Dinatriumdihydrogen(1-hydroxyethyliden)bisphosphonat
• Disodium (1-Hydroxyethylidene)Diphosphonate
• Disodium (1-Oh-Ethylidene)Bisphosphonate
• Disodium (1-hydroxyethylidene)-1,1-bisphosphonate
• Disodium (1-hydroxyethylidene)-1,1-diphosphonate
• Disodium 1-Hydroxyethylidene Phosphonate
• Disodium 1-hydroxy-1,1-ethanediphosphonate
• Disodium 1-hydroxyethane-1-diphosphonate
• Disodium 1-hydroxyethanediphosphonate
• Disodium 1-hydroxyethylidenediphosphonate
• Disodium Dihydrogen (1-Hydroxyethylidene)Bisphosphonate
• Disodium Dihydrogen (1-Hydroxyethylidene)Diphosphonate
• Disodium Ethanol-1,1-Diphosphonate
• Disodium Etidronate
• Disodium HEDP
• Disodium ethane-1-hydroxy-1,1-diphosphonate
• Disodium ethane-1-hydroxy-1,1-diphosphonic acid
• Disodium ethane-1-hydroxy-1-diphosphonate
• Disodium hydroxy-[1-hydroxy-1-(hydroxy-oxidophosphoryl)ethyl]phosphinate
• Disodium hydroxyethylidene diphosphonate
• Disodium of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid
• Disodium salt of 1-Hydroxy Ethylidene-1,1-DiphosphonicAcid
• Ethane-1-Hydroxy-1,1-Diphosphonic Acid, Disodium Salt
• Etidron
• Etidronate
• Etidronate Disodium
• Etidronate Sodium
• Etidronic Acid Disodium Salt
• Fostex NZ 2
• HEDP・Na2
• Hedp Disodium Salt
• Hydroxyethylidene diphosphonic acid disodium salt
• Ostedron
• Ph 212
• Phosphonic acid, (1-hydroxyethylidene)bis-,
• Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt
• Phosphonic acid, (1-hydroxyethylidene)di-, disodium salt
• Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2)
• Sequion 10Na2
• Sm-5600
• Sodium Ethidronate
• Sodium Ethydronate
• Sodium Etidronate
• Sodium ethane-1-hydroxy-1,1-diphosphonate
• Sodiumetidronate
• TF 133B (chelating agent)
• Tf 133B
• Turpinal 2NZ
• Xydifon
• phosphonate, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2)
• Etidronate Disodium (200 mg)
• sodiumethidronate
• disodiumethydronate
• didronelr
• DIPHOSPHONICACID,(1-HYDROXYETHYLENE)-,DISODIUMSALT
• (1-hydroxyethylidene)diphosphonicacid,disodiumsalt
• P,P'-(1-Hydroxyethylidene)bisphosphonic Acid SodiuM Salt
• ETIDRONATE DISODIUM (1-HYDROXYETHYLIDONE-1,1-DIPHOSPHONIC ACID DISODIUM SALT)
• 1-Hydroxyethylidene-1,1-bis-(phosphonic acid) disodium salt
• sodiumethydronate
• (1-hydroxyethane-1,1-diyl)di-phosphonicacidisodiumsalt
• disodium hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate
• DisodiuM Etidronate Hydrate
• (1-HYDROXYETHYLIDENE)BISPHOSPHONIC ACID
• Phosphonicacid,(1-hydroxyethylidene)bis-,disodiumsalt
• disodiumdihydrogen(1-hydroxyethylidene)diphosphonate
• 1-Hydroxyethylidone-1,1-diphosphonicacidtrisodiumsalt
• 1-Hydroxyethylidone-1,1-diphosphonicacid
• etidronate disodium，ETD
• Pentasodiumetidronate
• disodium1-hydroxyethylidenephosphonate
• ETRIDRONIC ACID, DISODIUM SALT
• ETIDRONATE DISODIUM USP(CRM STANDARD)
• (1-hydroxyethylidene)di-phosphonicacidisodiumsalt
• 1-Hydroxyethylidone-1,1-diphosphonicaciddisodiumsalt
• (1-hydroxyethane-1,1-diyl)diphosphonicaciddisodiumsalt
• Etidronate disodiuM hydrate
• ethane-1-hydroxy-1,1-diphosphonicacid,disodiumsalt
• DisodiuM of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDPNa2)
• disodiumethanol-1,1-diphosphonate
• 1-Hydroxyethylidone-1,1-diphosphonicacidpentasodiumsalt
• ethydronate disodium
• (1-hydroxyethylidene)bis-phosphonicacidisodiumsalt
• Phosphonicacid, P,P'-(1-hydroxyethylidene)bis-, sodiuM salt (1:2)
• (1-HYDROXYETHYLIDENE)BISPHONIC ACID
• Disodium 1-Hydroxyethane-1,1-diphosphonate
• Dihydrogen (1-hydroxyethylidene)bisphosphonate disodium hydrate
• DIHYDROGEN (1-HYDROXYETHYLIDENE)BISPHOSPHONATE DISODIUM
• disodium hydroxy-[1-hydroxy-1-[hydroxy(oxidanidyl)phosphoryl]ethyl]phosphinate
• (1-Hydroxyethane-1,1-diyl)diphosphonic acid disodi

Disodium Etidronate Hydrate

CAS: 7414-83-7

Formula: C₂H₆Na₂O₇P₂·xH₂O

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 249.99 (as Anhydrous)

Ref: 3B-D4159

Etidronate disodium

CAS: 7414-83-7

A bisphosphonate bone resorption inhibitor

Formula: C₂H₆Na₂O₇P₂

Molecular weight: 249.99

Ref: 02-J62381

ETIDRONATE DISODIUM CRS

CAS: 7414-83-7

ETIDRONATE DISODIUM CRS

Formula: C₂H₆Na₂O₇P₂

Color and Shape: Added

Molecular weight: 249.9919

Ref: 41-Y0000572

Sodium etidronate

CAS: 7414-83-7

Sodium etidronate (Didronel), a bisphosphonate, resists degradation, inhibits osteoclasts, and may boost bone formation.

Formula: C₂H₆Na₂O₇P₂

Purity: 99.5% - 99.75%

Color and Shape: Solid

Molecular weight: 249.99

Ref: TM-T1210

Disodium Etidronate Hydrate

CAS: 7414-83-7

Formula: C₂H₆Na₂O₇P₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 249.9919

Ref: IN-DA003PRC

Sodium etidronate

CAS: 7414-83-7

Sodium etidronate

Formula: C₂H₆Na₂O₇P₂

Purity: ≥98%

Molecular weight: 249.99

Ref: 54-BUP15901

Etidronate disodium salt

CAS: 7414-83-7

Formula: C₂H₆Na₂O₇P₂·xH₂O

Purity: ≥ 98.0% (dried basis)

Color and Shape: White powder

Molecular weight: 249.99 (anhydrous)

Ref: 7W-GP3560

Etidronic Acid Disodium Salt

Controlled Product

CAS: 7414-83-7

Applications Etidronic acid is used as a calcium regulator. Etidronic acid is a bisphosphonate antiresorptive agent.
References Francis, M.D., et al.: Science, 165, 1264 (1969), Jowsey, J., et al.: J. Lab. Clin. Med. , 76, 126 (1970), Altman, R.D.: N. Engl. J. Med., 79, 583 (1985)

Formula: C₂H₆O₇P₂·2Na

Color and Shape: Neat

Molecular weight: 249.99

Ref: TR-E935000

Etidronate disodium

CAS: 7414-83-7

Atherosclerotic plaque inhibitor; anti-bone resorptive therapy

Formula: C₂H₆Na₂O₇P₂·xH₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 249.99 g/mol

Ref: 3D-FE35145

Etidronate disodium salt - Bio-X ™

CAS: 7414-83-7

Etidronate is a bisphosphate drug that is used to treat osteoporosis. It is an inhibitor of bone resorption and works by inhibiting the action of osteoclasts.

Formula: C₂H₈O₇P₂·2Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 249.99 g/mol

Ref: 3D-BE164429

Etidronic acid (disodium)

CAS: 7414-83-7

Purity: 98%

Molecular weight: 249.99

Ref: 10-F986704

Etidronate disodium hydrate

CAS: 7414-83-7

1-Hydroxyethane-1,1-diphosphonic acid disodium salt

Formula: C₂H₆Na₂O₇P₂

Purity: 98%

Molecular weight: 249.99

Ref: IN-DG1953

Etidronate Disodium (DISCONTINUED)

CAS: 7414-83-7

Other organo-phosphorous derivatives: salt of methylphosphonic acid and (aminoiminomethyl) urea (1:1)

Formula: C₂H₈O₇P₂·2Na

Color and Shape: White Powder

Molecular weight: 251.95407

Ref: 45-1268502