
CAS 744270-00-6
:Formula:C18H19N3S
InChI:InChI=1S/C18H19N3S/c1-2-4-14(5-3-1)12-15-6-9-21(10-7-15)17-16-8-11-22-18(16)20-13-19-17/h1-5,8,11,13,15H,6-7,9-10,12H2
InChI key:AJQCKNBBHOVJGO-UHFFFAOYSA-N
SMILES:C1CN(CCC1CC2=CC=CC=C2)C3=C4C=CSC4=NC=N3
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ML116
CAS:ML116 is a potent and selective STAT3 inhibitor.Formula:C18H19N3SPurity:99.49%Color and Shape:SolidMolecular weight:309.4294-Benzyl-1-{thieno[2,3-d]pyrimidin-4-yl}piperidine
CAS:4-Benzyl-1-(thieno[2,3-d]pyrimidin-4-yl)piperidine is a piperidine derivative that inhibits the growth of cancer cells. It has been shown to reduce tumor size and induce regression in mouse models of brain tumors. This drug also induces apoptosis in neural cells and has been used to study the relationship between transport and death. 4-benzyl-1-(thieno[2,3-d]pyrimidin-4-yl)piperidine binds to the constitutive activation domain of the signal transducer protein, inhibiting its activity and leading to cell death. It is also an agonist for nuclear transport, which may be responsible for its effect on glioma cells.Formula:C18H19N3SPurity:Min. 95%Molecular weight:309.4 g/mol




