CAS 74431-23-5

Imipenem monohydrate

Description:

Imipenem monohydrate is a broad-spectrum beta-lactam antibiotic belonging to the carbapenem class, primarily used to treat serious bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a wide range of gram-positive and gram-negative bacteria, including those resistant to other antibiotics. The monohydrate form indicates that each molecule of imipenem is associated with one molecule of water, which can influence its solubility and stability. Imipenem is typically administered in combination with cilastatin, a renal dehydropeptidase inhibitor, to prevent its rapid degradation in the kidneys. The compound is usually presented as a white to off-white crystalline powder, and it is soluble in water, which facilitates its intravenous administration. Due to its broad-spectrum activity, imipenem is often reserved for severe infections or cases where other antibiotics are ineffective, making it a critical option in the treatment of multidrug-resistant bacterial infections. However, its use must be carefully monitored to prevent the development of resistance.

Formula: C₁₂H₁₇N₃O₄S·H₂O

InChI: InChI=1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1

InChI key: InChIKey=GSOSVVULSKVSLQ-JJVRHELESA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])(CC1SCCNC=N)[H].O

Synonyms:

• (5R,6S)-3-[(2-{[(1E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
• (5R,6S)-3-[(2-{[(E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate (1:1)
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, monohydrate, [5R-[5α,6α(R*)]]-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, hydrate (1:1), (5R,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, monohydrate, (5R,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,6-(1-hydroxyethyl)-3-[[2-(iminomethyl)amino]ethyl]thio]-7-oxo-,monohydrate
• Imipenem hydrate
• Imipenem monohydrate
• N-Formimidoyl thienamycin monohydrate

Imipenem monohydrate, 95%

CAS: 74431-23-5

Imipenem monohydrate, 74431-23-5, is a broad-spectrum carbapenem antibiotic that interferes with the activity of penicillin-binding proteins. Learn more.

Formula: C₁₂H₁₇N₃O₄S•H₂O

Purity: 95%

Molecular weight: 317.36

Ref: 02-J66749

IMIPENEM CRS

CAS: 74431-23-5

IMIPENEM CRS

Formula: C₁₂H₁₇N₃O₄S

Color and Shape: Powder.

Molecular weight: 299.3461

Ref: 41-I0090000

Imipenem Monohydrate

CAS: 74431-23-5

Antibiotics nesoi

Formula: C₁₂H₁₇N₃O₄S·H₂O

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 317.10454

Ref: 45-1337809

Imipenem monohydrate

CAS: 74431-23-5

Imipenem monohydrate (Imipenem) is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall. Cost-effective and quality-assured.

Formula: C₁₂H₁₉N₃O₅S

Purity: 98.77% - 99.94%

Color and Shape: Off-White Nonhygroscopic Crytals

Molecular weight: 317.36

Ref: TM-T1505

(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate

CAS: 74431-23-5

Formula: C₁₂H₁₉N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.3614

Ref: IN-DA003QZS

Imipenem monohydrate

CAS: 74431-23-5

Imipenem monohydrate

Formula: C₁₂H₁₇N₃O₄S·H₂O

Purity: By hplc: 98.03% (Typical Value in Batch COA)

Color and Shape: light yellow powder

Molecular weight: 317.36135g/mol

Ref: 54-BII5001

Imipenem monohydrate

CAS: 74431-23-5

Imipenem monohydrate

Purity: ≥98%

Molecular weight: 317.36g/mol

Ref: 54-BUP17447

Imipenem

CAS: 74431-23-5

Formula: C₁₂H₁₇N₃O₄S·xH₂O

Purity: ≥ 97.5% (dried basis)

Color and Shape: White to light-yellow or beige powder

Molecular weight: 299.35 (anhydrous)

Ref: 7W-GA1119

Imipenem monohydrate, 98%, EP grade

CAS: 74431-23-5

Formula: C₁₂H₁₇N₃O₄S·H₂O

Purity: ≤ 0.3%

Color and Shape: White, almost white, or pale yellow powder

Molecular weight: 317.36

Ref: 7W-GA7773

Imipenem and Cilastatin sodium salt (1:1 mixture, with added sodium bicarbonate)

CAS: 74431-23-5, 81129-83-1

Purity: Imipenem (C12H17N3O4S): ≥ 400μg/mg

Color and Shape: White to pale yellow powder

Ref: 7W-GP8148

Imipenem, Monohydrate

Controlled Product

CAS: 74431-23-5

Formula: C₁₂H₁₇N₃O₄S·H₂O

Color and Shape: White To Light Yellow

Molecular weight: 317.36

Ref: TR-I465200

Imipenem monohydrate

CAS: 74431-23-5

Inhibitor of cell-wall synthesis; carbapenem class

Formula: C₁₂H₁₉N₃O₅S

Purity: (Hplc) 98.0 To 101.0%

Color and Shape: Brown White Yellow Powder

Molecular weight: 317.36 g/mol

Ref: 3D-AI24560

δ1-Imipenem

Controlled Product

CAS: 74431-23-5

Formula: C₁₂H₁₇N₃O₄S

Color and Shape: Neat

Molecular weight: 299.346

Ref: TR-I465205

Imipenem Monohydrate, Antibiotic for Culture Media Use Only

CAS: 74431-23-5

Imipenem acts as an antimicrobial through inhibiting cell wall synthesis of various gram-positive and gram-negative bacteria. It remains very stable in the presence of beta-lactamase (both penicillinase andcephalosporinase) produced by some bacteria, and is a strong inhibitor of beta-lactamases from some gram-negative bacteria that are resistant to most beta-lactam antibiotics.

Formula: C₁₂H₁₉N₃O₅S

Purity: Min. 98.0 Area-%

Molecular weight: 317.36 g/mol

Ref: 3D-I-0500

Imipenem monohydrate

CAS: 74431-23-5

Imipenem monohydrate

Formula: C₁₂H₁₇N₃O₄S·H₂O

Purity: 95% (nmr) (Typical Value in Batch COA)

Color and Shape: yellow solid

Molecular weight: 317.36g/mol

Ref: 54-OR2453