CAS 74431-23-5: Imipenem monohydrate

Description: Imipenem monohydrate is a broad-spectrum beta-lactam antibiotic belonging to the carbapenem class, primarily used to treat serious bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a wide range of gram-positive and gram-negative bacteria, including those resistant to other antibiotics. The monohydrate form indicates that each molecule of imipenem is associated with one molecule of water, which can influence its solubility and stability. Imipenem is typically administered in combination with cilastatin, a renal dehydropeptidase inhibitor, to prevent its rapid degradation in the kidneys. The compound is usually presented as a white to off-white crystalline powder, and it is soluble in water, which facilitates its intravenous administration. Due to its broad-spectrum activity, imipenem is often reserved for severe infections or cases where other antibiotics are ineffective, making it a critical option in the treatment of multidrug-resistant bacterial infections. However, its use must be carefully monitored to prevent the development of resistance.

Formula: C₁₂H₁₇N₃O₄S·H₂O

InChI: InChI=1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1

InChI key: InChIKey=GSOSVVULSKVSLQ-JJVRHELESA-N

SMILES: O=C(O)C1=C(SCCNC=N)CC2N1C(=O)C2C(O)C.O

Synonyms:

• (5R,6S)-3-[(2-{[(1E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
• (5R,6S)-3-[(2-{[(E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate (1:1)
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, monohydrate, [5R-[5α,6α(R*)]]-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, hydrate (1:1), (5R,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, monohydrate, (5R,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,6-(1-hydroxyethyl)-3-[[2-(iminomethyl)amino]ethyl]thio]-7-oxo-,monohydrate
• Imipenem hydrate
• Imipenem monohydrate
• N-Formimidoyl thienamycin monohydrate

Imipenem monohydrate, 95%

CAS: 74431-23-5

Imipenem monohydrate is a broad spectrum B-lactam antibiotic. This Thermo Scientific Chemicals brand product was …

• Formula: C₁₂H₁₇N₃O₄S•H₂O
• Purity: 95%
• Molecular weight: 317.36

Imipenem CRS

CAS: 74431-23-5

• Formula: C₁₂H₁₇N₃O₄S
• Color and Shape: Powder.
• Molecular weight: 299.3461

Imipenem Monohydrate

CAS: 74431-23-5

Antibiotics nesoi

• Formula: C₁₂H₁₇N₃O₄S·H₂O
• Color and Shape: White Off-White Crystalline Powder
• Molecular weight: 317.10454

Imipenem monohydrate

CAS: 74431-23-5

Imipenem monohydrate (Imipenem) is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell …

• Formula: C₁₂H₁₉N₃O₅S
• Purity: 98.77% - 99.94%
• Color and Shape: Off-White Nonhygroscopic Crytals
• Molecular weight: 317.36

(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate

CAS: 74431-23-5

• Formula: C₁₂H₁₉N₃O₅S
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 317.36136

Imipenem monohydrate

CAS: 74431-23-5

• Formula: C₁₂H₁₇N₃O₄S·H₂O
• Purity: By hplc: 98.03% (Typical Value in Batch COA)
• Color and Shape: light yellow powder
• Molecular weight: 317.36g/mol

Imipenem

CAS: 74431-23-5

• Formula: C₁₂H₁₇N₃O₄S·xH₂O
• Purity: ≥ 97.5% (dried basis)
• Color and Shape: White to light-yellow or beige powder
• Molecular weight: 299.35 (anhydrous)

Imipenem monohydrate

CAS: 74431-23-5

• Purity: ≥98%
• Molecular weight: 317.36g/mol

Imipenem monohydrate, 98%, EP grade

CAS: 74431-23-5

• Formula: C₁₂H₁₇N₃O₄S·H₂O
• Purity: ≤ 0.3%
• Color and Shape: White, almost white, or pale yellow powder
• Molecular weight: 317.36

Imipenem monohydrate, 98%

CAS: 74431-23-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Purity: 98%
• Color and Shape: Off-white to light yellow, Powder

Imipenem monohydrate

CAS: 74431-23-5

• Formula: C₁₂H₁₇N₃O₄S·H₂O
• Purity: 95% (nmr) (Typical Value in Batch COA)
• Color and Shape: yellow solid
• Molecular weight: 317.36g/mol

Imipenem and Cilastatin sodium salt (1:1 mixture, with added sodium bicarbonate)

CAS: 74431-23-581129-83-1

• Purity: Imipenem (C12H17N3O4S): ≥ 400μg/mg
• Color and Shape: White to pale yellow powder

Imipenem, Monohydrate

CAS: 74431-23-5

• Formula: C₁₂H₁₇N₃O₄S·H₂O
• Color and Shape: White To Light Yellow
• Molecular weight: 317.36

Imipenem monohydrate

CAS: 74431-23-5

Inhibitor of cell-wall synthesis; carbapenem class

• Formula: C₁₂H₁₉N₃O₅S
• Purity: Min. 95%
• Color and Shape: Brown White Yellow Powder
• Molecular weight: 317.36 g/mol

δ1-Imipenem

CAS: 74431-23-5

• Formula: C₁₂H₁₇N₃O₄S
• Color and Shape: Neat
• Molecular weight: 299.346

Imipenem Monohydrate, Antibiotic for Culture Media Use Only

CAS: 74431-23-5

Imipenem acts as an antimicrobial through inhibiting cell wall synthesis of various gram-positive and gram-negative …

• Formula: C₁₂H₁₉N₃O₅S
• Purity: Min. 98.0 Area-%
• Molecular weight: 317.36 g/mol