CAS 74431-23-5
:Imipenem monohydrate
Description:
Imipenem monohydrate is a broad-spectrum beta-lactam antibiotic belonging to the carbapenem class, primarily used to treat serious bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a wide range of gram-positive and gram-negative bacteria, including those resistant to other antibiotics. The monohydrate form indicates that each molecule of imipenem is associated with one molecule of water, which can influence its solubility and stability. Imipenem is typically administered in combination with cilastatin, a renal dehydropeptidase inhibitor, to prevent its rapid degradation in the kidneys. The compound is usually presented as a white to off-white crystalline powder, and it is soluble in water, which facilitates its intravenous administration. Due to its broad-spectrum activity, imipenem is often reserved for severe infections or cases where other antibiotics are ineffective, making it a critical option in the treatment of multidrug-resistant bacterial infections. However, its use must be carefully monitored to prevent the development of resistance.
Formula:C12H17N3O4S·H2O
InChI:InChI=1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
InChI key:InChIKey=GSOSVVULSKVSLQ-JJVRHELESA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])(CC1SCCNC=N)[H].O
Synonyms:- (5R,6S)-3-[(2-{[(1E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
- (5R,6S)-3-[(2-{[(E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate (1:1)
- 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, monohydrate, [5R-[5α,6α(R*)]]-
- 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, hydrate (1:1), (5R,6S)-
- 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, monohydrate, (5R,6S)-
- 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,6-(1-hydroxyethyl)-3-[[2-(iminomethyl)amino]ethyl]thio]-7-oxo-,monohydrate
- Imipenem hydrate
- Imipenem monohydrate
- N-Formimidoyl thienamycin monohydrate
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Imipenem monohydrate, 95%
CAS:Imipenem monohydrate, 74431-23-5, is a broad-spectrum carbapenem antibiotic that interferes with the activity of penicillin-binding proteins. Learn more.Formula:C12H17N3O4S•H2OPurity:95%Molecular weight:317.36Imipenem Monohydrate
CAS:Antibiotics nesoiFormula:C12H17N3O4S·H2OColor and Shape:White Off-White Crystalline PowderMolecular weight:317.10454Imipenem monohydrate
CAS:Imipenem monohydrateFormula:C12H17N3O4S·H2OPurity:By hplc: 98.03% (Typical Value in Batch COA)Color and Shape:SolidMolecular weight:317.36135Imipenem monohydrate
CAS:Imipenem monohydrate (Imipenem) is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall. Cost-effective and quality-assured.Formula:C12H19N3O5SPurity:98.57% - 99.94%Color and Shape:Yellow SolidMolecular weight:317.361Imipenem
CAS:Formula:C12H17N3O4S·xH2OPurity:≥ 97.5% (dried basis)Color and Shape:White to light-yellow or beige powderMolecular weight:299.35 (anhydrous)Imipenem monohydrate
CAS:Imipenem monohydrateFormula:C12H19N3O5SPurity:99.5%Color and Shape:SolidMolecular weight:317.36Imipenem monohydrate, 98%, EP grade
CAS:Formula:C12H17N3O4S·H2OPurity:≤ 0.3%Color and Shape:White, almost white, or pale yellow powderMolecular weight:317.36Imipenem monohydrate (Standard)
CAS:Imipenem monohydrate (Standard) is a reference standard for research and analysis in studies involving Imipenem monohydrate. Imipenem monohydrate (Imipenem) is a carbapenem antibiotic isolated from the microorganism Streptomyces cattleya, and is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall, and is a broadly effective inhibitor of a wide range of Gram-positive and negative bacteria.Formula:C12H19N3O5SMolecular weight:317.361(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
CAS:Formula:C12H19N3O5SPurity:97%Color and Shape:SolidMolecular weight:317.3614Imipenem, Monohydrate
CAS:Controlled ProductFormula:C12H17N3O4S·H2OColor and Shape:NeatMolecular weight:317.36Imipenem and Cilastatin sodium salt (1:1 mixture, with added sodium bicarbonate)
CAS:Purity:Imipenem (C12H17N3O4S): ≥ 400μg/mgColor and Shape:White to pale yellow powder(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
CAS:(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrateFormula:C12H19N3O5SPurity:98%Molecular weight:317.36Imipenem monohydrate
CAS:Inhibitor of cell-wall synthesis; carbapenem class
Formula:C12H19N3O5SPurity:(Hplc) 98.0 To 101.0%Color and Shape:Brown White Yellow PowderMolecular weight:317.36 g/mol
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