CAS 7481-89-2

Dideoxycytidine

Description:

Dideoxycytidine, also known as ddC or zalcitabine, is a synthetic nucleoside analog of cytidine, primarily used as an antiviral medication in the treatment of HIV/AIDS. Its chemical structure features a modified sugar moiety, lacking the 2' and 3' hydroxyl groups, which renders it unable to participate in DNA chain elongation during replication. This characteristic makes it an effective inhibitor of viral reverse transcriptase, thereby preventing the replication of the virus. Dideoxycytidine is typically administered orally and is known for its potential side effects, including peripheral neuropathy and lactic acidosis. The compound is classified as a nucleoside reverse transcriptase inhibitor (NRTI) and is often used in combination with other antiretroviral agents to enhance therapeutic efficacy and reduce the risk of resistance. Its pharmacokinetics involve rapid absorption and distribution, with metabolism primarily occurring in the liver. Overall, dideoxycytidine represents an important tool in the management of HIV infection, contributing to improved patient outcomes when used appropriately.

Formula: C₉H₁₃N₃O₃

InChI: InChI=1/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8?/m0/s1

InChI key: InChIKey=WREGKURFCTUGRC-POYBYMJQSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)CC2)C=CC(N)=N1

Synonyms:

• 1-(2',3'-Dideoxy-Beta-Ribofuranosyl)Cytosine
• 2,3-Didesoxycytidine
• 2’,3’-Dideoxy-Cytidin
• 2′,3′-Dideoxycytidine
• 4-Amino-1-[(2R,5S)-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One
• 4-amino-1-[(5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one
• 4-amino-1-[5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one
• Beta-D-2',3'-Dideoxycytidine
• Cytidine, 2',3'-dideoxy-
• Cytidine, 2′,3′-dideoxy-
• D 2C
• DDC
• Dideoxycytidine
• Hivid
• Nsc 606170
• Ro 24-2027/000
• Zalcitabine
• 2',3'-dideoxy cytidi
• 2',3'-DIDEOXYCYTIDINE
• 2'',3''-DIDEOXYCYTIDINE(ZALCITABINE)
• DC
• I-livid
• ddCyd
• ZALCITABINE [2'',3''-DIDEOXYCYTIDINE]
• 2',3'-Dideoxy-D-cytidine
• Zalcitabine (200 mg)
• 2',3'-ddC
• 4-AMino-1-((2R,5S)-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one
• 4-Amino-1-(2,3-dideoxy-β-D-ribofuranosyl)pyrimidine-2(1H)-one
• Zalcitabine(2'-3'-dideoxycytidine, ddC)
• 2',3'-Dideoxycytidine, 98+%
• Cytidine, 2',3'-dideoxy-(8CI, 9CI)
• 23Dideoxycytidine, Dideoxycytidine, ddCyd, Hivid
• 1-(2,3-Dideoxy-beta-D-ribofuranosyl)cytosine
• 2',3'-DIDEOXYCYTIDINE extapure
• 3'-Dideoxycytidine

2',3'-Dideoxycytidine

CAS: 7481-89-2

Formula: C₉H₁₃N₃O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 211.22

Ref: 3B-D6431

2',3'-Dideoxycytidine, 98+%

CAS: 7481-89-2

2',3'-Dideoxycytidine, 98+%

Formula: C₉H₁₃N₃O₃

Purity: 98+%

Color and Shape: White to pale cream, Crystals or crystalline powder or powder

Molecular weight: 211.22

Ref: 02-L10619

Zalcitabine

CAS: 7481-89-2

Zalcitabine (ddC) is a nucleoside analog inhibiting HIV by blocking reverse transcriptase and halting viral DNA synthesis.

Formula: C₉H₁₃N₃O₃

Purity: 99.08% - ≥95%

Color and Shape: Solid

Molecular weight: 211.22

Ref: TM-T0110

Zalcitabine

CAS: 7481-89-2

Zalcitabine

Formula: C₉H₁₃N₃O₃

Purity: 99.5%

Molecular weight: 211.22

Ref: 54-BUP13850

2',3'-Dideoxycytidine

CAS: 7481-89-2

2',3'-Dideoxycytidine

Formula: C₉H₁₃N₃O₃·ClH·H₂O

Purity: 99%

Color and Shape: Solid

Molecular weight: 265.69404

Ref: 54-BID2037

Zalcitabine

CAS: 7481-89-2

Formula: C₉H₁₃N₃O₃

Purity: ≥ 99.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 211.22

Ref: 7W-GP2291

Dideoxycytidine

CAS: 7481-89-2

Formula: C₉H₁₃N₃O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 211.2178

Ref: IN-DA0058W1

Zalcitabine

Controlled Product

CAS: 7481-89-2

Applications A pyrimidine nucleoside analogue with antiviral activity.
References van der Vliet, P.C. and Kwant, M.M.: Biochemistry, 20, 2628 (1981), Mitsuya, H., Broder, S.: Proc. Nat. Acad. Sci. USA, 83, 1911 (1986), Starnes, M.C., and Cheng, Y.: J. Biol. Chem., 262, 988 (1987),

Formula: C₉H₁₃N₃O₃

Color and Shape: Neat

Molecular weight: 211.22

Ref: TR-Z140000

4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

CAS: 7481-89-2

4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

Formula: C₉H₁₃N₃O₃

Purity: 99%

Molecular weight: 211.22

Ref: IN-DG6953

Zalcitabine

CAS: 7481-89-2

Formula: C₉H₁₃N₃O₃

Molecular weight: 211.22

Ref: 4Z-Z-020001

2',3'-Dideoxycytidine

CAS: 7481-89-2

Anti-viral; reverse transcriptase inhibitor

Formula: C₉H₁₃N₃O₃

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 211.22 g/mol

Ref: 3D-ND06559

Zalcitabine - Bio-X ™

CAS: 7481-89-2

Zalcitabine (also known as dideoxycytidine or ddC) is a nucleoside analogue reverse transcriptase inhibitor (NRTI) medication used in the treatment of human immunodeficiency virus (HIV) infections. It works by blocking reverse transcriptase, an enzyme essential for replication of the HIV virus, thereby preventing the virus from multiplying and spreading. Zalcitabine is often used in combination with other antiretroviral drugs to effectively treat HIV/AIDS.

Formula: C₉H₁₃N₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 211.22 g/mol

Ref: 3D-BD164564

Zalcitabine

CAS: 7481-89-2

Formula: C₉H₁₃N₃O₃

Color and Shape: Solid

Molecular weight: 211.22

Ref: BE-RMCZ002000

4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

CAS: 7481-89-2

Formula: C₉H₁₃N₃O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 211.221

Ref: 10-F222318

2,3-Dideoxycytidine (ddC) extrapure, 98%

CAS: 7481-89-2

Formula: C₉H₁₃N₃O₃

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 211.22

Ref: SR-47248

Zalcitabine-13C,15N2

Controlled Product

CAS: 7481-89-2

Formula: C₈CH₁₃NN₂O₃

Color and Shape: Neat

Molecular weight: 364.39

Ref: TR-Z140002