CAS 751-03-1

Obacunone

Description:

Obacunone is a natural compound classified as a limonoid, primarily derived from the seeds of the fruit of the Citrus genus, particularly from the species Citrus obacunone. It is characterized by its complex tetracyclic structure, which includes a fused ring system that contributes to its biological activity. Obacunone exhibits a range of pharmacological properties, including anti-inflammatory, anti-cancer, and anti-microbial effects, making it a subject of interest in medicinal chemistry and natural product research. The compound is typically found in low concentrations in citrus fruits, and its extraction and purification can be challenging due to its structural complexity. In terms of physical properties, obacunone is generally a colorless to pale yellow solid with a characteristic odor. Its solubility varies, being more soluble in organic solvents than in water. The study of obacunone continues to reveal its potential applications in pharmaceuticals and functional foods, highlighting the importance of natural compounds in drug discovery and development.

Formula: C₂₆H₃₀O₇

InChI: InChI=1S/C26H30O7/c1-22(2)16-12-17(27)25(5)15(23(16,3)9-7-18(28)32-22)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)33-20/h7-9,11,13,15-16,19-20H,6,10,12H2,1-5H3/t15-,16+,19+,20-,23-,24+,25+,26-/m1/s1

InChI key: InChIKey=MAYJEFRPIKEYBL-OASIGRBWSA-N

SMILES: C[C@]12[C@]34[C@](O3)(C(=O)O[C@H]([C@]4(C)CC[C@@]1([C@]5(C)[C@@](CC2=O)(C(C)(C)OC(=O)C=C5)[H])[H])C=6C=COC6)[H]

Synonyms:

• (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione
• (5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione
• (5aR,7aS,8R,10aS,11aR,11bR)-8-(furan-3-yl)-12,12-dihydroxy-1,1,5a,7a,11b-pentamethyl-5a,5b,6,7,7a,8,11b,12,13,13a-decahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10(1H,10aH)-dione
• 14,15:21,23-Diepoxy-4,4,8-trimethyl-A,<span class="text-smallcaps">D</span>-dihomo-24-nor-4,17-dioxachola-1,20,22-triene-3,7,16-trione
• Ai3-37934
• Ccris 8657
• Obacunoic acid 3,4-lactone
• Obacunoic acid, eta-lactone
• Obacunoic acid, ε-lactone
• Obacunon
• Obakunone
• Oxireno(4,4a)-2-benzopyrano(6,5-g)(2)benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aαH,4bH,6H)-trione, 1α-(3-furyl)-1,6aα,7,11a,11bα,12,13,13a-octahydro-4bβ,7,7,11aβ,13aα-pentamethyl-
• Tricoccin S₃
• [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione

Obacunone

CAS: 751-03-1

Obacunone

Formula: C₂₆H₃₀O₇

Purity: 98%

Molecular weight: 454.51

Ref: 54-OR1023060

OBACUNON

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 454.5122

Ref: IN-DA00G2A6

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Molecular weight: 454.52

Ref: 7W-GY8065

Obacunone

CAS: 751-03-1

Obacunone

Formula: C₂₆H₃₀O₇

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 454.51

Ref: 54-BUP10739

Obacunone

CAS: 6483-15-4, 751-03-1

Formula: C₂₆H₃₀O₇

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 454.52

Ref: 3B-O0506

Obacunone

CAS: 751-03-1

Obacunone is a novel activator of Nrf2, which exhibits anti-cancer, anti-inflammatory, antivirulence, insecticidal, anti-proliferative and anti-aromatase activities. Obacunone stimulates muscle hypertrophy and prevents obesity and hyperglycemia, and that these beneficial effects are likely to be mediated through the activation of TGR5 and inhibition of PPARγ transcriptional activity. Obacunone significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM, and it also inhibits the p38 MAPK signaling pathway.

Formula: C₂₆H₃₀O₇

Purity: 95%~99%

Molecular weight: 454.519

Ref: BP-BP1018

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Molecular weight: 454.52

Ref: 4Z-O-086001

Obacunone

CAS: 751-03-1

Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.

Formula: C₂₆H₃₀O₇

Purity: 98% - ≥95%

Color and Shape: White Powder

Molecular weight: 454.51

Ref: TM-T3390

Obacunone

CAS: 751-03-1

Lactone

Formula: C₂₆H₃₀O₇

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 454.52

Ref: 5G-80509

Obacunone

CAS: 751-03-1

Obacunone is a naturally occurring limonoid, which is a type of triterpenoid compound. It is derived from the peels of citrus plants, particularly bitter and sweet oranges. Obacunone operates through several mechanisms, including inducing apoptosis, inhibiting cell proliferation, and modulating various signaling pathways. Its biological activity has garnered attention for its potential therapeutic benefits.

Formula: C₂₆H₃₀O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 454.51 g/mol

Ref: 3D-FO65314

OBACUNONE

CAS: 751-03-1

Purity: 98%

Molecular weight: 454.5190125

Ref: 10-F795475

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Molecular weight: 454.52

Ref: ST-EA-CP-O89000