CAS 75225-50-2
:Lovastatin sodium salt
Description:
Lovastatin sodium salt is a pharmacologically active compound primarily used as a cholesterol-lowering agent. It belongs to the class of statins, which function by inhibiting the enzyme HMG-CoA reductase, a key player in the biosynthesis of cholesterol in the liver. This compound is typically presented as a white to off-white powder and is soluble in water, which facilitates its formulation in various pharmaceutical preparations. Lovastatin sodium salt exhibits a molecular formula that reflects its complex structure, characterized by a lactone ring and a hydroxy acid moiety, contributing to its biological activity. The compound is often utilized in the management of hyperlipidemia and cardiovascular diseases, demonstrating efficacy in reducing low-density lipoprotein (LDL) cholesterol levels. Additionally, it may have pleiotropic effects, including anti-inflammatory properties. As with many medications, potential side effects can include muscle pain, liver enzyme alterations, and gastrointestinal disturbances, necessitating monitoring during therapy. Overall, Lovastatin sodium salt plays a significant role in modern medicine for cholesterol management.
Formula:C24H38O6·Na
InChI:InChI=1S/C24H38O6.Na/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28;/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28);/t14-,15-,16-,18+,19+,20-,21-,23-;/m0./s1
InChI key:InChIKey=PDWLGNSFYLIXBF-AXHZAXLDSA-N
SMILES:C(C[C@H](C[C@H](CC(O)=O)O)O)[C@@H]1[C@]2([C@@H](OC([C@H](CC)C)=O)C[C@@H](C)C=C2C=C[C@@H]1C)[H].[Na]
Synonyms:- 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, [1S-[1α(βS*,δS*),2α,6β,8β(R*),8aα]]-
- 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, sodium salt (1:1), (βR,δR,1S,2S,6R,8S,8aR)-
- 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-[(2S)-2-methyl-1-oxobutoxy]-, monosodium salt, (βR,δR,1S,2S,6R,8S,8aR)-
- Lovastatin sodium salt
- MSD 803, sodium salt
- Mb 530B
- Monacolin K sodium salt
- Sodium mevinolinate
- sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
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Found 9 products.
Lovastatin Hydroxy Acid, Sodium Salt
CAS:Formula:C24H37NaO6Purity:99%Color and Shape:SolidMolecular weight:444.5367Lovastatin hydroxy acid (sodium)
CAS:<p>Lovastatin hydroxy acid (sodium)</p>Purity:98%Molecular weight:444.54g/molLovastatin EP Impurity B Sodium Salt (Lovastatin Hydroxy Acid Sodium Salt)
CAS:Formula:C24H37O6·NaColor and Shape:White To Off-White SolidMolecular weight:421.55 22.99(3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-[[(2S)-2-methylbutanoyl]oxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid Sodium Salt (Lovastatin Hydroxy Acid Sodium Salt)
CAS:Controlled ProductFormula:C24H37O6·NaColor and Shape:NeatMolecular weight:444.54Lovastatin Hydroxy Acid, Sodium Salt
CAS:Controlled ProductFormula:C24H37O6·NaColor and Shape:NeatMolecular weight:444.54Lovastatin hydroxy acid, sodium salt
CAS:<p>Lovastatin is a chemical species belonging to the chemical class of statins. It inhibits cholesterol synthesis by inhibiting the enzyme HMG-CoA reductase, which is involved in converting mevalonate to isoprene and farnesyl pyrophosphate. Lovastatin has been shown to be effective against a number of bacterial strains, including E. coli, Salmonella enterica serovar Typhimurium, and Helicobacter pylori. This drug has been shown to be active against HIV-1 and human papillomavirus (HPV), with potent inhibitory activity at low doses. Lovastatin also inhibits the production of neutrophil chemotactic protein 1 (PD-L1) in cells infected with human cytomegalovirus (HCMV). The major metabolite of lovastatin is pravastatin, which exhibits similar properties but weaker potency.END></p>Formula:C24H37NaO6Purity:Min. 97 Area-%Molecular weight:444.54 g/molLovastatin hydroxy acid sodium
CAS:<p>Lovastatin Sodium is an HMG-CoA reductase inhibitor.</p>Formula:C24H38NaO6Color and Shape:SolidMolecular weight:445.54









