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CAS 75225-50-2

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Lovastatin sodium salt

Description:
Lovastatin sodium salt is a pharmacologically active compound primarily used as a cholesterol-lowering agent. It belongs to the class of statins, which function by inhibiting the enzyme HMG-CoA reductase, a key player in the biosynthesis of cholesterol in the liver. This compound is typically presented as a white to off-white powder and is soluble in water, which facilitates its formulation in various pharmaceutical preparations. Lovastatin sodium salt exhibits a molecular formula that reflects its complex structure, characterized by a lactone ring and a hydroxy acid moiety, contributing to its biological activity. The compound is often utilized in the management of hyperlipidemia and cardiovascular diseases, demonstrating efficacy in reducing low-density lipoprotein (LDL) cholesterol levels. Additionally, it may have pleiotropic effects, including anti-inflammatory properties. As with many medications, potential side effects can include muscle pain, liver enzyme alterations, and gastrointestinal disturbances, necessitating monitoring during therapy. Overall, Lovastatin sodium salt plays a significant role in modern medicine for cholesterol management.
Formula:C24H38O6·Na
InChI:InChI=1S/C24H38O6.Na/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28;/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28);/t14-,15-,16-,18+,19+,20-,21-,23-;/m0./s1
InChI key:InChIKey=PDWLGNSFYLIXBF-AXHZAXLDSA-N
SMILES:C(C[C@H](C[C@H](CC(O)=O)O)O)[C@@H]1[C@]2([C@@H](OC([C@H](CC)C)=O)C[C@@H](C)C=C2C=C[C@@H]1C)[H].[Na]
Synonyms:
  • 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, [1S-[1α(βS*,δS*),2α,6β,8β(R*),8aα]]-
  • 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, sodium salt (1:1), (βR,δR,1S,2S,6R,8S,8aR)-
  • 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-[(2S)-2-methyl-1-oxobutoxy]-, monosodium salt, (βR,δR,1S,2S,6R,8S,8aR)-
  • Lovastatin sodium salt
  • MSD 803, sodium salt
  • Mb 530B
  • Monacolin K sodium salt
  • Sodium mevinolinate
  • sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
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Found 10 products.