CAS 753498-25-8
:Indacaterol maleate
Description:
Indacaterol maleate is a long-acting beta-2 adrenergic agonist primarily used in the management of chronic obstructive pulmonary disease (COPD) and asthma. It is characterized by its ability to relax bronchial smooth muscle, leading to bronchodilation and improved airflow. The substance is a white to off-white powder that is soluble in water and exhibits a pKa value indicative of its ionization properties. Indacaterol maleate has a relatively long half-life, allowing for once-daily dosing, which enhances patient compliance. Its mechanism of action involves selective stimulation of beta-2 adrenergic receptors, resulting in reduced airway resistance. The maleate salt form is utilized to improve the stability and solubility of the active compound. As with other beta-agonists, potential side effects may include cardiovascular effects, tremors, and hypokalemia, necessitating careful monitoring in patients with pre-existing conditions. Overall, indacaterol maleate represents a significant advancement in the pharmacological treatment of obstructive airway diseases.
Formula:C28H32N2O7
InChI:InChI=1S/C24H28N2O3.C4H4O4/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24;5-3(6)1-2-4(7)8/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29);1-2H,(H,5,6)(H,7,8)/b;2-1-/t22-;/m0./s1
InChI key:IREJFXIHXRZFER-PCBAQXHCSA-N
SMILES:[C@@H](CNC1CC=2C(C1)=CC(CC)=C(CC)C2)(O)C3=C4C(=C(O)C=C3)NC(=O)C=C4.C(=C\C(O)=O)\C(O)=O
Synonyms:- 2(1H)-Quinolinone, 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-, (2Z)-2-butenedioate (1:1)
- 2(1H)-Quinolinone, 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-, (2Z)-2-butenedioate (1:1) (salt)
- Arcapta
- Hirobriz Breezhaler
- Indacaterol maleate
- Onbrez
- Onbrez Breezhaler
- Oslif Breezhaler
- Qab 149Afa
- [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxooxolan-2-yl]methyl benzoate
- Indacaterol maleate salt
- 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone Maleic Acid
- Indacaterol Maleic Acid Salt
- 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone (2Z)-2-butenedioate
- Indacaterol maleate, 98%, an ultra-long-acting β-adrenoceptor agonist
- QAB 149 Maleic Acid
- (R)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one maleate
- ndacaterol Maleate
- Indacaterol Maleate(API)
- IndacaterolMaleate>
- Indacaterol Maleate USP/EP/BP
- See more synonyms
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
Found 9 products.
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Formula:C28H32N2O7Purity:99.03% - 99.67%Color and Shape:SolidMolecular weight:508.5629Indacaterol Maleate
CAS:Formula:C24H28N2O3·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:392.50 116.07Indacaterol Maleic Acid Salt
CAS:Controlled ProductApplications A long-acting β2 adrenoreceptor agonist and bronchodilator, for the treatment of asthma and chronic obstructive pulmonary disease.
References Currie, G.P. et al.: Curr. Opin. Invest. Drugs., 7, 457 (2006); Naline, E. et al.: Eur. Resp. J., 29, 575 (2007); Roig, J. et al.: Open Resp. Med. J., 3, 27 (2009);Formula:C24H28N2O3·C4H4O4Color and Shape:NeatMolecular weight:508.56Indacaterol maleate
CAS:Controlled ProductLong-acting β2-agonist; bronchodilatorFormula:C24H28N2O3·C4H4O4Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:508.56 g/molRef: IN-DA00G3OP
Discontinued product
