CAS: 755037-03-7 - 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide

Formula: C₂₁H₁₅ClF₄N₄O₃

InChI: InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)

InChI key: InChIKey=FNHKPVJBJVTLMP-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(Cl)C(=C1)C(F)(F)F)NC2=CC=C(OC=3C=CN=C(C3)C(=O)NC)C=C2F

Synonyms:

• 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
• 4-[4-[N′-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic acid methylamide
• 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide
• Bay 73-4506
• Regorafenib
• Stivarga

Regorafenib

CAS: 755037-03-7

• Formula: C₂₁H₁₅ClF₄N₄O₃
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 482.82

2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-

CAS: 755037-03-7

• Formula: C₂₁H₁₅ClF₄N₄O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 482.8154

Regorafenib-13C-d3

CAS: 755037-03-7

• Formula: C₂₀₁₃CH₁₂D₃ClF₄N₄O₃
• Color and Shape: Pink Solid
• Molecular weight: 486.83

Regorafenib

CAS: 755037-03-7

• Formula: C₂₁H₁₅ClF₄N₄O₃
• Purity: ≥ 98.0% (dried basis)
• Color and Shape: White to off-white powder
• Molecular weight: 482.82

Regorafenib

CAS: 755037-03-7

• Formula: C₂₁H₁₅ClF₄N₄O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 482.82

Regorafenib

CAS: 755037-03-7

Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, …

• Formula: C₂₁H₁₅ClF₄N₄O₃
• Purity: 98% - 99.95%
• Color and Shape: Solid
• Molecular weight: 482.82

4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

CAS: 755037-03-7

• Purity: 99.0%
• Color and Shape: Solid
• Molecular weight: 482.82000732421875

Regorafenib

CAS: 755037-03-7

Applications It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of …

• Formula: C₂₁H₁₅ClF₄N₄O₃
• Color and Shape: Off White Powder
• Molecular weight: 482.82

Regorafenib

CAS: 755037-03-7

Multi-kinase inhibitor; inhibits epoxide hydrolase; antineoplastic

• Formula: C₂₁H₁₅ClF₄N₄O₃
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 482.82 g/mol

Regorafenib N-β-D-Glucuronide Sodium Salt

CAS: 755037-03-7

Applications Regorafenib N-β-D-Glucuronide Sodium Salt, is a derivative of Regorafenib (R143000); a compound that inhibits …

• Formula: C₂₇H₂₂ClF₄N₄O₉·Na
• Color and Shape: Neat
• Molecular weight: 680.92

Regorafenib (1-(4-Chloro-3-(trifluoromethyl)phenyl)urea)trimer

CAS: 755037-03-7

• Formula: C₄₉H₃₁Cl₃F₁₀N₈O₇
• Color and Shape: Neat
• Molecular weight: 1140.163