CAS: 755038-65-4 - Volasertib

Formula: C₃₄H₅₀N₈O₃

InChI: InChI=1S/C34H50N8O3/c1-6-28-33(44)39(4)29-20-35-34(38-31(29)42(28)22(2)3)37-27-14-9-24(19-30(27)45-5)32(43)36-25-10-12-26(13-11-25)41-17-15-40(16-18-41)21-23-7-8-23/h9,14,19-20,22-23,25-26,28H,6-8,10-13,15-18,21H2,1-5H3,(H,36,43)(H,35,37,38)/t25-,26-,28-/m1/s1

InChI key: InChIKey=SXNJFOWDRLKDSF-STROYTFGSA-N

SMILES: O=C(NC1CCC(N2CCN(CC2)CC3CC3)CC1)C4=CC=C(NC5=NC=C6C(=N5)N(C(C(=O)N6C)CC)C(C)C)C(OC)=C4

Synonyms:

• N-[trans-4-[4-(Cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxybenzamide
• Benzamide, N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-
• Volasertib
• BI 6727

Volasertib (BI 6727)

CAS: 755038-65-4

• Formula: C₃₄H₅₀N₈O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 618.8126

Volasertib

CAS: 755038-65-4

Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic …

• Formula: C₃₄H₅₀N₈O₃
• Purity: 98% - 99.72%
• Color and Shape: Solid
• Molecular weight: 618.81

Volasertib

CAS: 755038-65-4

Volasertib is a drug that inhibits the ATP-binding cassette transporter, which blocks the exit of …

• Formula: C₃₄H₅₀N₈O₃
• Purity: Min. 95%
• Molecular weight: 618.81 g/mol

Volasertib

CAS: 755038-65-4

Applications Volasertib (BI 6727) is a highly potent Polo-like kinase (PLK) inhibitor. References Rudolph, D., …

• Formula: C₃₄H₅₀N₈O₃
• Color and Shape: Neat
• Molecular weight: 618.81

Volasertib-D3

CAS: 755038-65-4

• Formula: C₃₄D₃H₄₇N₈O₃
• Color and Shape: Neat
• Molecular weight: 621.831