CAS 75581-11-2

4-Iodo-1-methoxy-2-methylbenzene

Description:

4-Iodo-1-methoxy-2-methylbenzene, also known as p-iodo-o-methoxytoluene, is an organic compound characterized by its aromatic structure, which includes a methoxy group (-OCH3) and an iodine atom attached to a methyl-substituted benzene ring. The presence of the iodine atom contributes to its reactivity, making it useful in various chemical synthesis processes, particularly in the field of medicinal chemistry and organic synthesis. The methoxy group enhances the compound's solubility in organic solvents and can influence its electronic properties, affecting reactivity and stability. This compound typically appears as a colorless to pale yellow liquid or solid, depending on the temperature and purity. It is important to handle it with care due to potential toxicity associated with halogenated compounds. Additionally, its applications may include serving as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic materials. Proper safety measures should be observed when working with this compound, including the use of personal protective equipment and adherence to relevant safety guidelines.

Formula: C₈H₉IO

InChI: InChI=1S/C8H9IO/c1-6-5-7(9)3-4-8(6)10-2/h3-5H,1-2H3

InChI key: InChIKey=FKBRRGQXYZMUNC-UHFFFAOYSA-N

SMILES: O(C)C1=C(C)C=C(I)C=C1

Synonyms:

• 1-Iodo-4-methoxy-3-methylbenzene
• 4-Iodo-2-methyl-1-methoxybenzene
• 4-Iodo-2-methylanisole
• 4-Methoxy-3-methyliodobenzene
• 5-Iodo-2-methoxytoluene
• Benzene, 4-iodo-1-methoxy-2-methyl-
• 4-Iodo-1-methoxy-2-methylbenzene

4-Iodo-1-methoxy-2-methylbenzene

CAS: 75581-11-2

Formula: C₈H₉IO

Purity: 96%

Color and Shape: Solid

Molecular weight: 248.0609

Ref: IN-DA008PUY

4-Iodo-1-methoxy-2-methylbenzene

CAS: 75581-11-2

4-Iodo-1-methoxy-2-methylbenzene

Purity: 98%

Molecular weight: 248.06g/mol

Ref: 54-OR80489

4-Iodo-2-methylanisole

CAS: 75581-11-2

4-Iodo-2-methylanisole (4IM) is a naphthalene that is regiospecifically eliminated after activation by nitrate in an acidic medium. The hydrochloride salt of 4IM, koenigicine, has been shown to produce estrogen levels in the female rat similar to those produced by 17β-estradiol. The synthesis of 4IM involves the nitration of 2-methylanisole followed by iodine oxidation. This reaction produces a mixture of mono-, di-, and tri-iodonapthalenes. The product obtained from this reaction is purified with column chromatography or recrystallization.
Theory predicts that 4IM will be oxidized to 4-iodo-2,6-dimethylanisole by terpene oxidants such as acetonitrile or ozone.

Formula: C₈H₉IO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 248.06 g/mol

Ref: 3D-FI64636

4-Iodo-1-methoxy-2-methylbenzene

CAS: 75581-11-2

Formula: C₈H₉IO

Purity: 95%

Color and Shape: Solid

Molecular weight: 248.063

Ref: 10-F330077