CAS 75695-93-1: Isradipine

Description: Isradipine is a dihydropyridine calcium channel blocker primarily used in the treatment of hypertension and angina pectoris. It functions by selectively inhibiting L-type calcium channels, leading to vasodilation and reduced peripheral vascular resistance. Isradipine is characterized by its ability to lower blood pressure without significantly affecting heart rate. The compound is typically administered orally and has a relatively long half-life, allowing for once or twice daily dosing. Its chemical structure includes a dihydropyridine ring, which is essential for its pharmacological activity. Isradipine is known for its favorable side effect profile compared to other antihypertensive agents, although it may still cause peripheral edema, dizziness, or flushing in some patients. The substance is metabolized in the liver, primarily through cytochrome P450 enzymes, and is excreted mainly in the urine. Overall, Isradipine represents an important therapeutic option in cardiovascular medicine, particularly for patients requiring effective blood pressure management.

Formula: C₁₉H₂₁N₃O₅

InChI: InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3

InChI key: InChIKey=HMJIYCCIJYRONP-UHFFFAOYSA-N

SMILES: O=C(OC)C1=C(NC(=C(C(=O)OC(C)C)C1C2=CC=CC3=NON=C32)C)C

Synonyms:

• 2,1,3-Benzoxadiazole, 3,5-pyridinedicarboxylic acid deriv.
• 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-(1-methylethyl) ester
• 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester
• 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester
• 3-O-Methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• Clivoten
• DynaCirc
• DynaCirc CR
• DynaCire
• DynaCire CR
• Dynacrine
• Esradin
• Isopropyl methyl (+-)-4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
• Isradipin
• Isradipine [USAN:INN:BAN]
• Isradipino
• Isradipino [Spanish]
• Isradipinum
• Isradipinum [Latin]
• Isrodipine
• Lomir
• Pn 200
• Pn 200-110
• Prescal
• Rebriden
• Unii-Yo1Uk1S598
• (+-)-Isradipine

Isradipine

CAS: 75695-93-1

• Formula: C₁₉H₂₁N₃O₅
• Purity: >98.0%(HPLC)
• Color and Shape: Light orange to Yellow to Green powder to crystal
• Molecular weight: 371.39

Isradipine, 98+%

CAS: 75695-93-1

Isradipine is a L-type calcium channel blocker, Isradipine has anti-atherosclerotic effects in animals and improves …

• Formula: C₁₉H₂₁N₃O₅
• Purity: 98+%
• Color and Shape: Powder or crystals or crystalline powder
• Molecular weight: 371.39

Isradipine

CAS: 75695-93-1

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 371.39300537109375

Isradipine CRS

CAS: 75695-93-1

• Formula: C₁₉H₂₁N₃O₅
• Color and Shape: Crystalline Powder. Yellow. Powder.
• Molecular weight: 371.3871

Isradipine

CAS: 75695-93-1

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₁₉H₂₁N₃O₅
• Color and Shape: Powder
• Molecular weight: 371.39

Isradipine

CAS: 75695-93-1

• Formula: C₁₉H₂₁N₃O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 371.3871

Isradipine

CAS: 75695-93-1

• Purity: ≥98%
• Molecular weight: 371.39g/mol

Isradipine

CAS: 75695-93-1

• Formula: C₁₉H₂₁N₃O₅
• Molecular weight: 371.39

Isradipine

CAS: 75695-93-1

• Purity: 98%
• Molecular weight: 371.39g/mol

Isradipine d3

CAS: 75695-93-1

• Formula: C₁₉H₁₈N₃O₅D₃
• Molecular weight: 374.41

Isradipine

CAS: 75695-93-1

• Formula: C₁₉H₂₁N₃O₅
• Molecular weight: 371.40

Isradipine

CAS: 75695-93-1

• Formula: C₁₉H₂₁N₃O₅
• Color and Shape: Neat
• Molecular weight: 371.39

Isradipine-d7

CAS: 75695-93-1

• Formula: C₁₉H₁₄N₃O₅D₇
• Molecular weight: 378.44

Isradipine-d6

CAS: 75695-93-1

• Formula: C₁₉H₁₅N₃O₅D₆
• Molecular weight: 377.43

Isradipine

CAS: 75695-93-1

Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and …

• Formula: C₁₉H₂₁N₃O₅
• Purity: 99.65% - 99.84%
• Color and Shape: Yellow Solid
• Molecular weight: 371.39

Isradipine

CAS: 75695-93-1

Applications Isradipine is a dihydropyridine calcium channel blocker. Antihypertensive and antianginal. References Nelson, E.B., et …

• Formula: C₁₉H₂₁N₃O₅
• Color and Shape: Neat
• Molecular weight: 371.39

Isradipine

CAS: 75695-93-1

• Formula: C₁₉H₂₁N₃O₅
• Purity: 99.6%
• Color and Shape: Off-White
• Molecular weight: 371.14812

Isradipine

CAS: 75695-93-1

L-type calcium channel blocker

• Formula: C₁₉H₂₁N₃O₅
• Purity: Min. 95%
• Color and Shape: Yellow Powder
• Molecular weight: 371.39 g/mol