CAS 75738-58-8

Cefmenoxime hydrochloride

Description:

Cefmenoxime hydrochloride is a semi-synthetic cephalosporin antibiotic that belongs to the beta-lactam class of antibiotics. It is primarily used for the treatment of various bacterial infections due to its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. The compound exhibits stability against certain beta-lactamases, which enhances its efficacy against resistant strains. Cefmenoxime hydrochloride is typically administered via injection and is known for its favorable pharmacokinetic properties, including good tissue penetration and a relatively long half-life, allowing for less frequent dosing. The substance is characterized by its ability to inhibit bacterial cell wall synthesis, leading to cell lysis and death. Common side effects may include gastrointestinal disturbances, allergic reactions, and potential impacts on renal function. As with other antibiotics, it is essential to use cefmenoxime hydrochloride judiciously to minimize the risk of developing antibiotic resistance. Proper storage conditions are necessary to maintain its stability and efficacy, typically requiring protection from light and moisture.

Formula: C₃₂H₃₅ClN₁₈O₁₀S₆

InChI: InChI=1/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h2*5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b2*21-8-;/t2*9-,13-;/m11./s1

InChI key: InChIKey=HZYJYGJIOCXOTH-FAIYLGIWSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC=4N(C)N=NN4)[H].Cl

Synonyms:

• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride (2:1)
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)-
• 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride
• 7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride
• Abbott 50192
• Bestcall
• Bestron
• Cefmax
• Cefmenoxime Hcl
• Cefmenoxime hemihydrochloride
• Cefmenoxime.1.5 HCl
• Cemix
• SCE-1365(free acid)
• Tacef
• Cefmenoxime hydrochloride
• Cefmenoxime  Hydrochloride
• CefMenoxiMe SodiuM
• ab50912hemihydrochloride
• hydrochloride(2:1),(6r-(6-alpha,7-beta(z)))-o
• CEFMENOXIME HEMIHYDROCHLORIDE;SCE-1365 HEMIHYDROCHLORIDE
• 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
• cefmenoximehemihydrochloride
• CefMenoxiMe HCL Sterile (pure)
• Hydrochloride (syn-isomer)
• )(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-ox
• SCE-1365 hemihydrochloride
• (6R,7R)-7-[[(2Z)-(2-AMino-4-thiazolyl)(MethoxyiMino)acetyl]aMino]-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid HeMihydrochloride
• (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride(2:1)
• 2Cefmenoxime·Hydrochloride
• Cefmenoxime Hydrochloride (350 mg)
• sce1365hydrochloride
• Cefmenoxime hydrochloride USP/EP/BP
• (6R)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid·0.5hydrochloride

Cefmenoxime hydrochloride

CAS: 75738-58-8

Cefmenoxime hydrochloride: cephalosporin antibiotic, IV/IM, targets gram-positive/negative bacteria, beta-lactamase resistant, effective, low side effects.

Formula: C₃₂H₃₅ClN₁₈O₁₀S₆

Purity: 98.02% - 98.41%

Color and Shape: Solid

Molecular weight: 1059.58

Ref: TM-T1190

Cefmenoxime hydrochloride

CAS: 75738-58-8

Cefmenoxime hydrochloride

Purity: ≥98%

Molecular weight: 1059.58g/mol

Ref: 54-BUP14928

Cefmenoxime hydrochloride

CAS: 75738-58-8

Formula: C₁₆H₁₈ClN₉O₅S₃

Molecular weight: 548.02

Ref: 7W-GA5301

Cefmenoxime HCl

CAS: 75738-58-8

Formula: C₁₆H₁₇N₉O₅S₃·5HCl

Molecular weight: 511.55 0.5 36.46

Ref: 4Z-C-312001

Cefmenoxime Hydrochloride

Controlled Product

CAS: 75738-58-8

Applications A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.
References Yakota, N. et al.: Jpn. J. Antibiot., 48, 602 (1995); Fukuda, M. et al.: Jpn. J. Ophthamol., 46, 384 (2002);

Formula: C₁₆H₁₇N₉O₅S₃·ClH

Color and Shape: Neat

Molecular weight: 1059.58

Ref: TR-C242835

Cefmenoxime hydrochloride

CAS: 75738-58-8

Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating gynecological and obstetric infections.

Formula: C₁₆H₁₇N₉O₅S₃HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 529.79 g/mol

Ref: 3D-FC19858