CAS 75738-58-8
:Cefmenoxime hydrochloride
Description:
Cefmenoxime hydrochloride is a semi-synthetic cephalosporin antibiotic that belongs to the beta-lactam class of antibiotics. It is primarily used for the treatment of various bacterial infections due to its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. The compound exhibits stability against certain beta-lactamases, which enhances its efficacy against resistant strains. Cefmenoxime hydrochloride is typically administered via injection and is known for its favorable pharmacokinetic properties, including good tissue penetration and a relatively long half-life, allowing for less frequent dosing. The substance is characterized by its ability to inhibit bacterial cell wall synthesis, leading to cell lysis and death. Common side effects may include gastrointestinal disturbances, allergic reactions, and potential impacts on renal function. As with other antibiotics, it is essential to use cefmenoxime hydrochloride judiciously to minimize the risk of developing antibiotic resistance. Proper storage conditions are necessary to maintain its stability and efficacy, typically requiring protection from light and moisture.
Formula:C32H35ClN18O10S6
InChI:InChI=1/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h2*5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b2*21-8-;/t2*9-,13-;/m11./s1
InChI key:InChIKey=HZYJYGJIOCXOTH-FAIYLGIWSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC=4N(C)N=NN4)[H].Cl
Synonyms:- (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride (2:1)
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), [6R-[6α,7β(Z)]]-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)-
- 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride
- 7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride
- Abbott 50192
- Bestcall
- Bestron
- Cefmax
- Cefmenoxime Hcl
- Cefmenoxime hemihydrochloride
- Cefmenoxime.1.5 HCl
- Cemix
- SCE-1365(free acid)
- Tacef
- Cefmenoxime hydrochloride
- Cefmenoxime Hydrochloride
- CefMenoxiMe SodiuM
- ab50912hemihydrochloride
- hydrochloride(2:1),(6r-(6-alpha,7-beta(z)))-o
- CEFMENOXIME HEMIHYDROCHLORIDE;SCE-1365 HEMIHYDROCHLORIDE
- 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
- cefmenoximehemihydrochloride
- CefMenoxiMe HCL Sterile (pure)
- Hydrochloride (syn-isomer)
- )(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-ox
- SCE-1365 hemihydrochloride
- (6R,7R)-7-[[(2Z)-(2-AMino-4-thiazolyl)(MethoxyiMino)acetyl]aMino]-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid HeMihydrochloride
- (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride(2:1)
- 2Cefmenoxime·Hydrochloride
- Cefmenoxime Hydrochloride (350 mg)
- sce1365hydrochloride
- Cefmenoxime hydrochloride USP/EP/BP
- (6R)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid·0.5hydrochloride
- See more synonyms
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5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)-
CAS:Formula:C16H18ClN9O5S3Purity:98%Color and Shape:SolidMolecular weight:548.0194Cefmenoxime hydrochloride
CAS:Cefmenoxime hydrochloride: cephalosporin antibiotic, IV/IM, targets gram-positive/negative bacteria, beta-lactamase resistant, effective, low side effects.Formula:C32H35ClN18O10S6Purity:98.02% - 99.95%Color and Shape:White SolidMolecular weight:1059.58Cefmenoxime hydrochloride
CAS:Cefmenoxime hydrochlorideFormula:C32H35ClN18O10S6Purity:≥98%Molecular weight:1059.58Cefmenoxime Hydrochloride
CAS:Controlled ProductApplications A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.
References Yakota, N. et al.: Jpn. J. Antibiot., 48, 602 (1995); Fukuda, M. et al.: Jpn. J. Ophthamol., 46, 384 (2002);Formula:C16H17N9O5S3·ClHColor and Shape:NeatMolecular weight:1059.58Cefmenoxime hydrochloride
CAS:Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating gynecological and obstetric infections.Formula:C16H17N9O5S3HClPurity:Min. 95%Color and Shape:White PowderMolecular weight:529.79 g/mol
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