CAS: 75747-14-7 - (4Z,6Z,8S,9S,10Z,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Formula: C₃₁H₄₃N₃O₈

InChI: InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,19,24-25,27,29,33,36H,1,12-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9-,18-10+,20-15+/t17-,19+,24+,25+,27-,29+/m1/s1

InChI key: InChIKey=AYUNIORJHRXIBJ-TXHRRWQRSA-N

SMILES: O=C(OC1C(=CC(C)C(O)C(OC)CC(C)CC=2C(=O)C(=CC(=O)C2NCC=C)NC(=O)C(=CC=CC1OC)C)C)N

Synonyms:

• (4Z,6E,10E)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• (8R,9R,12R,13S,14R,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• (8S,9S,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• 17-(Allylamino)-17-demethoxygeldanamycin
• 17-(Allylamino)-17-desmethylgeldanamycin
• 17-(Allylamino)geldanamycin
• 17-Allylaminodemethoxygeldanamycin
• 17-Allylaminogeldanamycin
• 17-Demethoxy-17-(2-propenylamino)geldanamycin
• 17-Demethoxy-17-allylaminogeldanamycin
• 17-N-Allylamino-17-demethoxygeldanamycin
• 17Aag
• 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv.
• A 8476
• Bms 722782
• Cp 127374
• Geldanamycin, 17-demethoxy-17-(2-propenylamino)-
• Kos 953
• NSC 330507
• Tanespimycin

17-(Allylamino)-17-demethoxygeldanamycin, 99%

CAS: 75747-14-7

17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and …

• Formula: C₃₁H₄₃N₃O₈
• Purity: 99%
• Color and Shape: Red to dark red, Powder
• Molecular weight: 585.70

17-AAG

CAS: 75747-14-7

• Formula: C₃₁H₄₃N₃O₈
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 585.6884

17-(Allylamino)-17-demethoxygeldanamycin

CAS: 75747-14-7

• Formula: C₃₁H₄₃N₃O₈
• Purity: 98% (Typical Value in Batch COA)
• Color and Shape: brown solid
• Molecular weight: 585.69g/mol

17-Allylamino-17-Demethoxygeldanamycin-d5

CAS: 75747-14-7

• Formula: C₃₁H₃₈D₅N₃O₈
• Molecular weight: 590.73

Telatinib

CAS: 75747-14-7

• Formula: C₃₁H₄₃N₃O₈
• Purity: ≥ 98%
• Color and Shape: Red to dark red powder
• Molecular weight: 585.69

17-Allylamino-17-Demethoxygeldanamycin

CAS: 75747-14-7

• Formula: C₃₁H₄₃N₃O₈
• Molecular weight: 585.70

Tanespimycin

CAS: 75747-14-7

Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell …

• Formula: C₃₁H₄₃N₃O₈
• Purity: 99.07% - 99.83%
• Color and Shape: Dark Purple Solid
• Molecular weight: 585.69

17-(Allylamino-d5) Geldanamycin

CAS: 75747-14-7

Applications Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog …

• Formula: C₃₁D₅H₃₈N₃O₈
• Color and Shape: Neat
• Molecular weight: 590.719

17-AAG

CAS: 75747-14-7

M01354 - 17-AAG

• Formula: C₃₁H₄₃N₃O₈
• Purity: 98+%
• Color and Shape: Solid
• Molecular weight: 585.698

17-Allylaminogeldanamycin

CAS: 75747-14-7

17-AAG is the first clinically tested hsp90 inhibitor that exhibits antitumor activity. Its antitumor effects …

• Formula: C₃₁H₄₃N₃O₈
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 585.69 g/mol

17-(Allylamino) Geldanamycin

CAS: 75747-14-7

Applications Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog …

• Formula: C₃₁H₄₃N₃O₈
• Color and Shape: Neat
• Molecular weight: 585.69