CAS 75847-73-3

Enalapril

Description:

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is a prodrug that is converted in the body to its active form, enalaprilat. The chemical formula of enalapril is C20H28N2O5, and it features a carboxyl group, an amine group, and a phenyl ring, contributing to its pharmacological activity. Enalapril works by inhibiting the ACE enzyme, which leads to decreased production of angiotensin II, a potent vasoconstrictor, resulting in vasodilation and reduced blood pressure. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include cough, elevated potassium levels, and, in rare cases, angioedema. Enalapril is often prescribed in combination with other antihypertensive agents to enhance therapeutic efficacy. As with any medication, it is essential to monitor patients for potential adverse effects and interactions with other drugs.

Formula: C₂₀H₂₈N₂O₅

InChI: InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1

InChI key: InChIKey=GBXSMTUPTTWBMN-XIRDDKMYSA-N

SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CCC2

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-<smallcap>L</span>-alanyl]-, (S)-
• <span class="text-smallcaps">L</smallcap>-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-<smallcap>L</span>-alanyl-
• Enarenal
• N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</span>-proline
• N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline
• N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline (2Z)-but-2-enedioate
• Vaseretic
• Vasotec
• ；Amprace
• L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-
• L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-

Enalapril

CAS: 75847-73-3

Long-acting ACE inhibitor and antihypertensive

Formula: C₂₀H₂₈N₂O₅

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 376.45

Ref: 02-J60750

Enalapril

CAS: 75847-73-3

Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Formula: C₂₀H₂₈N₂O₅

Purity: 99.47%

Color and Shape: Solid

Molecular weight: 376.45

Ref: TM-T1605

Enalapril Maleate

CAS: 75847-73-3, 76095-16-4

Formula: C₂₀H₂₈N₂O₅·C₄H₄O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 492.53

Ref: 3B-E1010

Enalapril

CAS: 75847-73-3

Formula: C₂₀H₂₈N₂O₅

Molecular weight: 376.45

Ref: 4Z-E-0256

ENALAPRIL

CAS: 75847-73-3

Purity: 98%;RG

Molecular weight: 376.4530029

Ref: 10-F808738