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CAS 75847-73-3

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Enalapril

Description:
Enalapril is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is a prodrug that is converted in the body to its active form, enalaprilat. The chemical formula of enalapril is C20H28N2O5, and it features a carboxyl group, an amine group, and a phenyl ring, contributing to its pharmacological activity. Enalapril works by inhibiting the ACE enzyme, which leads to decreased production of angiotensin II, a potent vasoconstrictor, resulting in vasodilation and reduced blood pressure. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include cough, elevated potassium levels, and, in rare cases, angioedema. Enalapril is often prescribed in combination with other antihypertensive agents to enhance therapeutic efficacy. As with any medication, it is essential to monitor patients for potential adverse effects and interactions with other drugs.
Formula:C20H28N2O5
InChI:InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
InChI key:InChIKey=GBXSMTUPTTWBMN-XIRDDKMYSA-N
SMILES:C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CCC2
Synonyms:
  • <span class="text-smallcaps">L</smallcap>-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-<smallcap>L</span>-alanyl]-, (S)-
  • <span class="text-smallcaps">L</smallcap>-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-<smallcap>L</span>-alanyl-
  • Enarenal
  • N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</span>-proline
  • N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline
  • N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline (2Z)-but-2-enedioate
  • Vaseretic
  • Vasotec
  • ；Amprace
  • L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-
  • See more synonyms
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Found 6 products.