CAS 765317-72-4

3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1-benzofuran-6-sulfonamide

Description:

The chemical substance known as 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1-benzofuran-6-sulfonamide, with the CAS number 765317-72-4, is a complex organic compound characterized by its multi-functional groups and structural diversity. It features a benzofuran core, which is a fused ring system that contributes to its aromatic properties. The presence of sulfonamide and thiazole moieties indicates potential biological activity, possibly related to antimicrobial or anti-inflammatory effects. The dibromo and hydroxy substituents on the benzoyl group suggest enhanced reactivity and solubility, while the ethyl group may influence its lipophilicity. This compound's intricate structure may allow for specific interactions with biological targets, making it of interest in medicinal chemistry. Its synthesis and characterization would typically involve advanced organic synthesis techniques, and its properties could be evaluated through various analytical methods, including NMR, mass spectrometry, and chromatography. Overall, this compound exemplifies the complexity and potential utility of modern synthetic organic chemistry.

Formula: C₂₆H₁₉Br₂N₃O₇S₃

InChI: InChI=1/C26H19Br2N3O7S3/c1-2-21-23(24(32)14-11-19(27)25(33)20(28)12-14)18-8-7-17(13-22(18)38-21)41(36,37)30-15-3-5-16(6-4-15)40(34,35)31-26-29-9-10-39-26/h3-13,30,33H,2H2,1H3,(H,29,31)

InChI key: SXKBTDJJEQQEGE-UHFFFAOYSA-N

SMILES: CCc1c(c2ccc(cc2o1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nccs1)C(=O)c1cc(c(c(c1)Br)O)Br

Synonyms:

• 6-Benzofuransulfonamide, 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-
• 3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1-benzofuran-6-sulfonamide
• 3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide
• PTP1B-IN-4

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)benzofuran-6-sulfonamide

CAS: 765317-72-4

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)benzofuran-6-sulfonamide

Formula: C₂₆H₁₉Br₂N₃O₇S₃

Purity: 96%

Molecular weight: 741.46

Ref: 54-OR1074653

PTP1B Inhibitor

CAS: 765317-72-4

Formula: C₂₆H₁₉Br₂N₃O₇S₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 741.4480

Ref: IN-DA005KHJ

PTP1B-IN-4

CAS: 765317-72-4

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)benzofuran-6-sulfonamide

Formula: C₂₆H₁₉Br₂N₃O₇S₃

Purity: 96%

Molecular weight: 741.45

Ref: IN-DG162945

PTP1B Inhibitor

CAS: 765317-72-4

PTP1B Inhibitor is a drug that is used to treat type 2 diabetes. It inhibits the activation of PTP1B, a protein that regulates the uptake of glucose from the blood. This inhibition decreases insulin-stimulated glucose uptake and increases sodium-dependent glucose uptake in peripheral tissues. PTP1B Inhibitor is also known as an antidiabetic agent due to its ability to regulate insulin secretion and blood sugar levels. The hydrogen bonds between this drug and human protein are very stable, which makes it more difficult for enzymes to break down the complex. PTP1B Inhibitor has been shown to have an effect on fatty acid metabolism and signal pathways, leading to potential metabolic disorders such as obesity or type 2 diabetes.

Formula: C₂₆H₁₉Br₂N₃O₇S₃

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 741.45 g/mol

Ref: 3D-QFB31772

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1-benzofuran-6-sulfonamide

Controlled Product

CAS: 765317-72-4

Formula: C₂₆H₁₉Br₂N₃O₇S₃

Color and Shape: Neat

Molecular weight: 741.44

Ref: TR-D421300

PTP1B-IN-4

CAS: 765317-72-4

PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.

Formula: C₂₆H₁₉Br₂N₃O₇S₃

Purity: 98.19%

Color and Shape: Yellow Solid

Molecular weight: 741.45

Ref: TM-T24073