CAS 76931-93-6
:S-acetylthioglycolic acid N-*hydroxysuccinimide E
Description:
S-acetylthioglycolic acid N-hydroxysuccinimide ester, identified by the CAS number 76931-93-6, is a chemical compound that features a thiol group and an ester linkage, which contributes to its reactivity and utility in various biochemical applications. This compound is characterized by its ability to form stable conjugates with amines, making it valuable in bioconjugation processes, particularly in the development of drug delivery systems and targeted therapies. The presence of the N-hydroxysuccinimide (NHS) moiety enhances its reactivity towards primary amines, facilitating the formation of amide bonds. Additionally, the acetyl group provides a protective function, which can be removed under specific conditions to reveal the thiol group for further reactions. This compound is often used in the synthesis of peptide and protein conjugates, as well as in the modification of surfaces for biosensor applications. Overall, its unique structural features enable a range of applications in chemical biology and materials science.
Formula:C8H9NO5S
InChI:InChI=1/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3
InChI key:FLCQLSRLQIPNLM-UHFFFAOYSA-N
SMILES:CC(=O)SCC(=O)ON1C(=O)CCC1=O
Synonyms:- N-Succinimidyl S-Acetylthioglycolate [Cross-linking Reagent]
- Thioacetic acid S-[2-oxo-2-[(2,5-dioxopyrrolizino)oxy]ethyl] ester
- SATA Protein Modifier
- -Succinimidyl
- 2,5-Dioxopyrrolidin-1-yl 2-(acetylthio)
- S-ACETYLTHIOGLYCOLIC ACID N-HYDROXYSUCCI NIMIDE EST
- N-SuccinimidylS-Acetylthioglycolate[Cross-linkingReagent]>
- S-Acetylthioglycolic acid N-hydroxysuccinimide ester, tech.
- Ethanethioic Acid S-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl] Ester
- SATA
- SUCCINIMIDYL ACETYLTHIOACETATE
- S-acetylthioglycolic acid N-*hydroxysuccinimide E
- (2,5-dioxopyrrolidin-1-yl) 2-acetylsulfanylacetate
- Acetic 2-(2,5-dioxopyrrolidin-1-yl)acetic thioanhydride
- S-ACETYLTHIOGLYCOLIC ACID N-SUCCINIMIDYL ESTER
- 2,5-Dioxopyrrolidin-1-yl 2-(acetylthio)acetate
- (Acetylthio)acetic acid 2,5-dioxopyrrolidin-1-yl ester
- 2-bromo-1-[5-(2-bromo-1-oxoethyl)-1-naphthalenyl]ethanone
- S-Acetylthioglycolic acid N-hydroxysucciniMide ester >=95% (TLC), powder
- S-ACETYLTHIOACETIC ACID-N-HYDROXYSUCCINIMIDE ESTER
- -Acetylthioglycolate [Cross-linking Reagent]
- (SATA):N-succinimidyl S-acetylthioacetate
- 2-(Acetylthio)acetic acid succinimidyl ester
- SKL356
- N-Succinimidyl S-acetylthioacetate (SATA)
- Acetic acid, 2-(acetylthio)-, 2,5-dioxo-1-pyrrolidinyl ester
- N-Succinimidyl (acetylthio)acetate, N-Succinimidyl S-acetylthioglycolate, S-Acetylthioglycolic acid NHS ester
- N-SUCCINIMIDYL (ACETYLTHIO)ACETATE
- n-hydroxysuccinimides-acetylthioacetate
- S-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl} ethanethioate
- 2-MERCAPTOL[S-ACETYL]ACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
- 76931-93-6
- N-SUCCINIMIDYL S-ACETYLTHIOACETATE
- S-ACETYLTHIOGLYCOLIC ACID N-HYDROXYSUCCINIMIDE ESTER
- N
- S-Acetylthioglycolic acid NHS ester, SATA
- N-SUCCINIMIDYL S-ACETYLTHIOGLYCOLATE
- S
- S-ACETYLTHIOGLYCOLIC ACID NHS ESTER
- See more synonyms
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N-Succinimidyl S-Acetylthioglycolate [Cross-linking Reagent]
CAS:Formula:C8H9NO5SPurity:>94.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:231.22N-Succinimidyl S-acetylthioacetate
CAS:N-Succinimidyl S-acetylthioacetateFormula:C8H9NO5SColor and Shape:White to off white Solid-PowderMolecular weight:231.22576N-Succinimidyl-S-acetylthioacetate
CAS:N-Succinimidyl-S-acetylthioacetateFormula:C8H9NO5SPurity:≥95%Molecular weight:231.232,5-Dioxopyrrolidin-1-yl 2-(acetylthio)acetate
CAS:Formula:C8H9NO5SPurity:97%Color and Shape:SolidMolecular weight:231.2258N-Succinimidyl-S-acetylthioacetate
CAS:Controlled ProductStability Moisture Sensitive
Applications Reacts with primary amines to add protected sulfhydryls.
References Duncan, R.J.S., et al.: Anal. Biochem., 132, 68 (1983)Formula:C8H9NO5SColor and Shape:NeatMolecular weight:231.23N-Succinimidyl-S-acetylthioacetate
CAS:SATA adds protected sulfhydryl groups to proteins for later crosslinking reactions.Formula:C8H9NO5SPurity:99.72%Color and Shape:SolidMolecular weight:231.226N-Succinimidyl-S-acetylthioacetate
CAS:N-Succinimidyl-S-acetylthioacetate is an acetylating agent that has a reactive group, which is the succinimidyl ester. The chain reaction of this agent with thiols leads to the formation of acetic acid and a thioester. The reactivity of these molecules can be used to introduce functional groups onto proteins, such as polyclonal antibodies, b16 mouse melanoma cells, epidermal growth factor, and blood group antigens. N-Succinimidyl-S-acetylthioacetate reacts with lysine residues on the protein surface and human serum albumin by incorporating acetate groups into their amino acid chains. This agent can also be used in laboratory diagnosis for identifying bacteria and viruses.
Formula:C8H9NO5SPurity:Min. 95%Color and Shape:White PowderMolecular weight:231.23 g/mol2,5-Dioxopyrrolidin-1-yl 2-(acetylthio)acetate
CAS:Formula:C8H9NO5SPurity:97%Color and Shape:SolidMolecular weight:231.22N-Succinimidyl-S-acetylthioacetate
CAS:2,5-Dioxopyrrolidin-1-yl 2-(acetylthio)acetateFormula:C8H9NO5SPurity:98%Molecular weight:231.23
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