CAS 76939-46-3

8-bromoadenosine-3',5'-cyclophosphate sodium salt

Description:

8-Bromoadenosine-3',5'-cyclophosphate sodium salt is a cyclic nucleotide derivative of adenosine, characterized by the presence of a bromine atom at the 8-position of the adenine ring. This compound is known for its role as a biochemical tool in research, particularly in studies related to signal transduction pathways involving cyclic AMP (cAMP) and cyclic GMP (cGMP). The sodium salt form enhances its solubility in aqueous solutions, making it suitable for various biological assays. The cyclic phosphate structure contributes to its stability and ability to mimic natural signaling molecules, allowing it to interact with specific receptors and enzymes in cellular processes. Additionally, it is often used in pharmacological studies to investigate the effects of cyclic nucleotides on cellular functions such as proliferation, differentiation, and apoptosis. As with many synthetic compounds, proper handling and storage are essential to maintain its integrity and effectiveness in experimental applications.

Formula: C₁₀H₁₀BrN₅NaO₆P

InChI: InChI=1/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

SMILES: C1C2C(C(C(n3c4c(c(N)ncn4)nc3Br)O2)O)OP(=O)(O)O1.[Na]

Synonyms:

• 8-Bromo-cAMP, Sodium Salt
• 8-Bromoadenosine 3:5-Cyclic*Monophosphate Sodiu
• sodium (1S,6R,8R,9R)-8-(6-amino-8-bromo-purin-9-yl)-3-oxido-3-oxo-2,4,7-trioxa-3$l5-phosphabicyclo[4.3.0]nonan-9-ol

8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt

CAS: 76939-46-3

Formula: C₁₀H₁₀BrN₅NaO₆P

Purity: 98%

Color and Shape: Solid

Molecular weight: 430.0838

Ref: IN-DA0036N5

8-Bromo-cAMP sodium salt

CAS: 76939-46-3

8-Bromo-cAMP sodium salt

Formula: C₁₀H₁₀BrN₅NaO₆P

Purity: ≥98%

Molecular weight: 430.087

Ref: 54-BUP15580

8-Bromoadenosine 3'',5''-cyclic monophosphate sodium salt

CAS: 76939-46-3

Formula: C₁₀H₁₀BrN₅NaO₆P

Molecular weight: 430.08

Ref: 7W-GN3729

8-Bromo-cAMP sodium salt

CAS: 76939-46-3

8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.

Formula: C₁₀H₁₀BrN₅NaO₆P

Purity: 98% - 99.94%

Color and Shape: Off-White Powder

Molecular weight: 430.08

Ref: TM-T6747

8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt

CAS: 76939-46-3

Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.

Formula: C₁₀H₁₀BrN₅O₆P·Na

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 430.08 g/mol

Ref: 3D-NB07971

8-Bromo-cAMP Sodium Salt

Controlled Product

CAS: 76939-46-3

Stability Moisture Sensitive
Applications 8-Bromo-cAMP is a cAMP analog and cAMP-dependent PKA activator.

Formula: C₁₀H₁₀BrN₅NaO₆P

Color and Shape: Neat

Molecular weight: 430.08

Ref: TR-B693278