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CAS 77-67-8

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Ethosuximide

Description:
Ethosuximide is an anticonvulsant medication primarily used in the treatment of absence seizures, particularly in children. It is classified as a succinimide derivative and works by inhibiting T-type calcium channels in the thalamic neurons, which helps to stabilize neuronal activity and reduce seizure frequency. Ethosuximide is typically administered orally and is known for its relatively favorable side effect profile compared to other antiepileptic drugs. Physically, it appears as a white to off-white crystalline powder, and it is soluble in water and organic solvents like ethanol. The chemical formula of ethosuximide is C7H11N1O2S, and it has a molecular weight of approximately 159.24 g/mol. Common side effects may include gastrointestinal disturbances, fatigue, and dizziness, but serious adverse reactions are rare. Regular monitoring is recommended to assess therapeutic levels and potential side effects, especially during the initial stages of treatment. Overall, ethosuximide is a well-established medication in the management of absence seizures, contributing significantly to the quality of life for affected individuals.
Formula:C7H11NO2
InChI:InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
InChI key:InChIKey=HAPOVYFOVVWLRS-UHFFFAOYSA-N
SMILES:C(C)C1(C)C(=O)NC(=O)C1
Synonyms:
  • 2,5-Pyrrolidinedione, 3-ethyl-3-methyl-
  • 2-Ethyl-2-Methylsuccinimide
  • 2-Methyl-2-ethylsuccinimide
  • 3-Ethyl-3-methyl-2,5-pyrrolidinedione
  • 3-Ethyl-3-methylpyrrolidine-2,5-dione
  • 3-Ethyl-3-methylsuccinimide
  • 3-Methyl-3-ethylpyrrolidine-2,5-dione
  • 3-Methyl-3-ethylsuccinimide
  • Atysmal
  • Capitus
  • See more synonyms
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