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CAS 77-86-1

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Tris(hydroxymethyl)aminomethane

Description:
Tris(hydroxymethyl)aminomethane, commonly known as Tris, is an organic compound with the chemical formula C4H11NO3. It is a white crystalline solid that is highly soluble in water, making it an effective buffering agent in biochemical and molecular biology applications. Tris has a pKa value around 8.1, which allows it to maintain a stable pH in biological systems, particularly in the physiological range. It is often used in the preparation of buffer solutions for electrophoresis and other laboratory techniques. Tris is non-toxic and has low volatility, which contributes to its widespread use in research settings. Additionally, it can form stable complexes with metal ions, which can be advantageous in various biochemical assays. However, it is important to note that Tris can interfere with certain assays, particularly those involving phenolic compounds. Overall, Tris is a versatile and essential reagent in many scientific fields, particularly in biochemistry and molecular biology.
Formula:C4H11NO3
InChI:InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key:InChIKey=LENZDBCJOHFCAS-UHFFFAOYSA-N
SMILES:C(CO)(CO)(CO)N
Synonyms:
  • 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-amine
  • 2-Amino-1,3-dihydroxy-2-(hydroxymethyl)propane
  • 2-Amino-2-(Hydroxymethyl)-1,3-Propandiol
  • 2-Amino-2-(hydroxymethyl)-1,3-propanediol
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol
  • 2-Amino-2-(hydroxymethyl)propanediol
  • 2-Amino-2-hydroxymethyl-1, 3-propanediol
  • 2-Amino-2-hydroxymethylpropan-1,3-diol
  • 2-Amino-2-methylol-1,3-propanediol
  • A 0321
  • See more synonyms
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