CAS 77102-28-4

3-[[2-[(Aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)propanoic acid

Description:

3-[[2-[(Aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)propanoic acid, with CAS number 77102-28-4, is a complex organic compound characterized by its multifunctional structure, which includes amino, thiol, and carboxylic acid groups. This compound features a thioether linkage and a mercaptomethyl group, contributing to its reactivity and potential applications in biochemistry and medicinal chemistry. The presence of amino groups suggests that it can participate in various chemical reactions, including peptide bond formation and nucleophilic substitutions. Its thiol groups may also impart antioxidant properties, making it of interest in biological systems. The compound's solubility in water is likely due to the polar functional groups, which can engage in hydrogen bonding. Overall, this substance may serve as a valuable building block in the synthesis of more complex molecules or as a ligand in coordination chemistry, with potential implications in drug development and therapeutic applications.

Formula: C₇H₁₅N₃O₂S₂

InChI: InChI=1S/C7H15N3O2S2/c8-7(9)10-1-2-14-4-5(3-13)6(11)12/h5,13H,1-4H2,(H,11,12)(H4,8,9,10)

InChI key: InChIKey=AKPKWZRKZOAAAZ-UHFFFAOYSA-N

SMILES: C(CSCCNC(=N)N)(C(O)=O)CS

Synonyms:

• 3-[[2-[(Aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)propanoic acid
• DL-2-(Mercaptomethyl)-3-(guanidinoethyl)thiopropanoic acid
• Propanoic acid, 3-[[2-[(aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)-, (±)-
• Propanoic acid, 3-[[2-[(aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)-
• Plummer's carboxypeptidase inhibitor

Mergetpa

CAS: 77102-28-4

Stability Air Sensitive, Hygroscopic
Applications Mergetpa is a potent mercapto bi-product analogue inhibitor for human carboxypeptidase N. Carboxypeptidase N is a potent bradykinin and anaphylatoxin inactivator in plasma. Mergetpa improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis.
References Barenholz, Y., et al.: Biochemistry, 16, 2806 (1977), Eaton, D., et al.: J. Biol. Chem., 266, 21833 (1991), Tan, A., et al.: Biochemistry, 34, 5811 (1995),

Formula: C₇H₁₅N₃O₂S₂

Color and Shape: Neat

Molecular weight: 237.34

Ref: TR-M225170

DL-2-Mercaptomethyl-3-guanidinoethylthiopropanoic acid

CAS: 77102-28-4

DL-2-Mercaptomethyl-3-guanidinoethylthiopropanoic acid is a potent inhibitor of the enzyme, guanylate cyclase. It has been shown to inhibit the activity of this enzyme in a wide variety of tissues and cells, including gland cells, liver cells, and tumor cells. DL-2-Mercaptomethyl-3-guanidinoethylthiopropanoic acid has been shown to inhibit cell proliferation and induce apoptosis in both in vitro and in vivo models. DL-2-Mercaptomethyl-3-guanidinoethylthiopropanoic acid inhibits the production of peptide hormones by binding to their receptors. This drug also inhibits cellular receptor activity for basic proteins (e.g., growth factors) that are necessary for cancer cell proliferation and survival.

Formula: C₇H₁₅N₃O₂S₂

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 237.35 g/mol

Ref: 3D-FL171629

Mergetpa

CAS: 77102-28-4

Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].

Formula: C₇H₁₅N₃O₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 237.34

Ref: TM-T78239