CAS 77317-55-6

Methyl 2-amino-5-iodobenzoate

Description:

Methyl 2-amino-5-iodobenzoate, with the CAS number 77317-55-6, is an organic compound that belongs to the class of benzoate esters. It features a benzoic acid derivative where a methyl ester group is attached to the carboxylic acid, and an amino group is positioned at the 2nd carbon, while an iodine atom is substituted at the 5th carbon of the aromatic ring. This compound is characterized by its molecular structure, which includes both hydrophilic (the amino and ester groups) and hydrophobic (the aromatic ring) regions, influencing its solubility and reactivity. Methyl 2-amino-5-iodobenzoate may exhibit biological activity, making it of interest in medicinal chemistry and pharmaceutical research. Its iodine substituent can also enhance its reactivity in various chemical reactions, such as nucleophilic substitutions or coupling reactions. Safety data should be consulted for handling, as halogenated compounds can pose health risks. Overall, this compound serves as a valuable intermediate in organic synthesis and may have applications in drug development.

Formula: C₈H₈INO₂

InChI: InChI=1S/C8H8INO2/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4H,10H2,1H3

InChI key: InChIKey=NNXVARLKWUFGGG-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C(N)C=CC(I)=C1

Synonyms:

• 2-Amino-5-iodobenzoic acid methyl ester
• 5-Iodoanthranilic acid methyl ester
• Anthranilic acid, 5-iodo-, methyl ester
• Benzoic acid, 2-amino-5-iodo-, methyl ester
• Methyl 2-Amino-5-Iodobenzoate
• Methyl 5-iodoanthranilate

Methyl 2-Amino-5-iodobenzoate

CAS: 77317-55-6

Formula: C₈H₈INO₂

Purity: >98.0%(GC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 277.06

Ref: 3B-I0516

Methyl 2-amino-5-iodobenzoate

CAS: 77317-55-6

Formula: C₈H₈INO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 277.0591

Ref: IN-DA003RMY

Methyl 2-amino-5-iodobenzoate, min. 99%

CAS: 77317-55-6

Formula: C₈H₈INO₂

Purity: min. 99%

Color and Shape: White to yellow solid

Molecular weight: 277.06

Ref: 08-07-0121

Methyl 2-amino-5-iodobenzoate

CAS: 77317-55-6

Methyl 2-amino-5-iodobenzoate

Formula: C₈H₈INO₂

Purity: ≥95%

Color and Shape: white to off white solid

Molecular weight: 277.06g/mol

Ref: 54-OR4694

Methyl 2-amino-5-iodobenzoate

CAS: 77317-55-6

Formula: C₈H₈INO₂

Purity: 95%

Color and Shape: Crystalline

Molecular weight: 277.061

Ref: 10-F050602

2-Amino-5-iodobenzoic acid methyl ester

CAS: 77317-55-6

2-Amino-5-iodobenzoic acid methyl ester (2AIBA) is a molecule that can be used as an activatable probe for imaging cancer. It has a profile suitable for radionuclide therapy and is also senescent. 2AIBA binds to DNA and inhibits the synthesis of proteins, leading to cell death. 2AIBA has potent inhibitory activity against murine melanoma cells and synergistic effects when combined with acridone. The section of tumour cells was shown to be reduced by 42% in mice when treated with 2AIBA, acridone, and radiation compared to mice treated with radiation alone.

Formula: C₈H₈INO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 277.06 g/mol

Ref: 3D-FA55376