CAS 7778-01-0

3,5-Dichlorobenzyl bromide

Description:

3,5-Dichlorobenzyl bromide is an organic compound characterized by its aromatic structure, featuring a benzene ring substituted with two chlorine atoms at the 3 and 5 positions and a bromomethyl group. This compound is typically a colorless to pale yellow liquid with a distinctive odor. It is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the bromine atom, which can be replaced by various nucleophiles. The chlorine substituents contribute to the compound's electron-withdrawing properties, influencing its reactivity and stability. 3,5-Dichlorobenzyl bromide is used in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It is important to handle this compound with care, as it may pose health risks, including skin and respiratory irritation. Proper safety measures, including the use of personal protective equipment and working in a well-ventilated area, are essential when dealing with this chemical.

Formula: C₇H₅BrCl₂

InChI: InChI=1/C7H5BrCl2/c8-4-5-1-6(9)3-7(10)2-5/h1-3H,4H2

SMILES: c1c(cc(cc1Cl)Cl)CBr

Synonyms:

• 1-(Brommethyl)-3,5-dichlorbenzol
• 1-(Bromomethyl)-3,5-dichlorobenzene
• Benzene, 1-(bromomethyl)-3,5-dichloro-

1-(Bromomethyl)-3,5-dichlorobenzene

CAS: 7778-01-0

Formula: C₇H₅BrCl₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 239.92

Ref: 3B-D6130

1-(Bromomethyl)-3,5-dichlorobenzene

CAS: 7778-01-0

Formula: C₇H₅BrCl₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.9246

Ref: IN-DA0038FW

1-(Bromomethyl)-3,5-dichlorobenzene

CAS: 7778-01-0

1-(Bromomethyl)-3,5-dichlorobenzene

Formula: C₇H₅BrCl₂

Purity: 97%

Color and Shape: white to off-white solid

Molecular weight: 239.93g/mol

Ref: 54-OR90486

1-(Bromomethyl)-3,5-dichlorobenzene

CAS: 7778-01-0

Formula: C₇H₅BrCl₂

Purity: 95%

Molecular weight: 239.92

Ref: 10-F454912

5-(Bromomethyl)-1,3-dichlorobenzene

CAS: 7778-01-0

5-(Bromomethyl)-1,3-dichlorobenzene is a lead compound for the treatment of osteoarthritis. It inhibits aggrecanase and proteoglycanases, which are enzymes that break down proteins in cartilage. 5-(Bromomethyl)-1,3-dichlorobenzene has been shown to inhibit mmp-1 and tnf-α and to be selective for aggrecanase over other proteoglycanases. This drug also has anti-inflammatory properties due to its ability to inhibit cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 5-(Bromomethyl)-1,3-dichlorobenzene is a racemic mixture of two enantiomers (enantiomer 1 and enantiomer 2). Enantiomer 1 is more potent than enantiomer 2 at inhibiting aggrecanase and proteoglycanases.

Formula: C₇H₅BrCl₂

Purity: Min. 95%

Molecular weight: 239.93 g/mol

Ref: 3D-HAA77801