CAS 77883-43-3
:Doxazosin mesylate
Description:
Doxazosin mesylate is a pharmaceutical compound primarily used as an antihypertensive and an alpha-1 adrenergic antagonist. It is commonly prescribed for the treatment of hypertension and benign prostatic hyperplasia (BPH). The substance is characterized by its ability to selectively block alpha-1 adrenergic receptors, leading to vasodilation and a subsequent decrease in blood pressure. Doxazosin mesylate is typically administered in oral form and is known for its long half-life, allowing for once-daily dosing. The mesylate salt form enhances its solubility and stability, facilitating better absorption in the gastrointestinal tract. In terms of physical properties, doxazosin mesylate is a white to off-white crystalline powder, which is soluble in water and organic solvents. Its chemical structure includes a quinazoline ring, contributing to its pharmacological activity. As with any medication, potential side effects may include dizziness, fatigue, and orthostatic hypotension, necessitating careful monitoring during treatment.
Formula:C23H25N5O5·CH4O3S
InChI:InChI=1S/C23H25N5O5.CH4O3S/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20;1-5(2,3)4/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26);1H3,(H,2,3,4)
InChI key:InChIKey=VJECBOKJABCYMF-UHFFFAOYSA-N
SMILES:NC=1C2=C(N=C(N1)N3CCN(C(=O)C4OC=5C(OC4)=CC=CC5)CC3)C=C(OC)C(OC)=C2.S(C)(=O)(=O)O
Synonyms:- 1,4-Benzodioxin, piperazine deriv.
- 1-(4-Amino-6,7-Dimethoxy-2-Quinazolinyl)-4-(1,4-Benzodioxan-2-Ylcarbonyl) Piperazine Methanesulfonate
- 1-(4-Amino-6,7-Dimethoxy-2-Quinazolinyl)-4-[4-(1,4-Benzodioxan-2-Yl)Carpiperazin-1-Yl)]-6,7-Dimethoxyquinazoline Mesylate
- 2-[4-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine; methanesulfonic acid
- Alfadil
- Cardenalin
- Cardran
- Cardular
- Cardura
- Cardura (pharmaceutical)
- Cardura XL
- Carduran
- Diblocin
- Dosin
- Doxacard
- Doxacor
- Doxazolazine Mesylate
- Doxazosin Mesilate
- Doxazosin Methanesulfonate
- Doxazosin Meylate
- Doxazosin monomethanesulfonate
- Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)-, methanesulfonate (1:1)
- Normothen
- Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, monomethanesulfonate
- Supressin
- Uk-33274-27
- Doxazosin, Mesylate
- See more synonyms
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Found 16 products.
Doxazosin Mesylate
CAS:Formula:C23H25N5O5·CH4O3SPurity:>98.0%(HPLC)(N)Color and Shape:White to Light yellow powder to crystalMolecular weight:547.58Doxazosin mesilate
CAS:Doxazosin mesilateFormula:C24H29N5O8SPurity:99.2%Color and Shape:Off-WhiteMolecular weight:547.17368DOXAZOSIN MESILATE CRS
CAS:DOXAZOSIN MESILATE CRSFormula:C23H25N5O5Color and Shape:PowderMolecular weight:451.4751Doxazosin Mesylate
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C23H25N5O5·CH4O3SColor and Shape:White Tan PowderMolecular weight:547.58 g/molDoxazosin mesylate
CAS:Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.Formula:C24H29N5O8SPurity:99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:547.58Doxazosin mesylate
CAS:Formula:C23H25N5O5·CH3SO3HPurity:(HPLC) ≥ 97.0%Color and Shape:White to off-white powderMolecular weight:547.58Doxazosin Mesylate
CAS:<p>Stability Light Sensitive<br>Applications Doxazosin is a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.<br>References Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982), de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982),<br></p>Formula:C23H25N5O5·CH4O3SColor and Shape:White To Off-WhiteMolecular weight:547.58Doxazosin mesylate - Bio-X ™
CAS:<p>Doxazosin is a first-generation α1-adrenergic receptor antagonist that is used in the treatment of hypertension and urinary obstruction, It has been shown to be effective in combination therapy for patients with benign prostatic hyperplasia.</p>Formula:C23H25N5O5•CH4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:547.58 g/molDoxazosin mesylate
CAS:<p>α1-adrenoceptor blocker; anti-hypertensive agent</p>Formula:C24H29N5O8SPurity:Min. 95%Color and Shape:PowderMolecular weight:547.58 g/mol
