CAS 78110-38-0
:Aztreonam
Description:
Aztreonam is a synthetic monobactam antibiotic primarily used to treat infections caused by Gram-negative bacteria. It is characterized by its beta-lactam structure, which is essential for its antibacterial activity. Aztreonam is particularly effective against Pseudomonas aeruginosa and other Enterobacteriaceae, making it a valuable option for patients with penicillin allergies, as it has a low cross-reactivity with penicillins. The compound is typically administered intravenously or intramuscularly, as it is not well absorbed when taken orally. Aztreonam exhibits a unique mechanism of action by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Its stability against certain beta-lactamases, enzymes produced by bacteria to confer resistance, enhances its efficacy in treating resistant infections. Additionally, aztreonam has a favorable pharmacokinetic profile, with a relatively short half-life and good tissue penetration, allowing for effective treatment of various infections. However, like all antibiotics, it may cause side effects, including gastrointestinal disturbances and potential allergic reactions.
Formula:C13H17N5O8S2
InChI:InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1
InChI key:InChIKey=WZPBZJONDBGPKJ-VEHQQRBSSA-N
SMILES:N(C(/C(=N\OC(C(O)=O)(C)C)/C1=CSC(N)=N1)=O)[C@H]2[C@H](C)N(S(=O)(=O)O)C2=O
Synonyms:- (2S,3S)-3-({(2E)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-2-methyl-4-oxoazetidine-1-sulfonate
- (2S-(2-Alpha,3-Beta(Z)))-Dinyl)Amino)-2-Oxoethylidene)Amino)Oxy)-2-Methyl
- 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
- 2-({[1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
- 2-[({(1E)-1-(2-amino-1,3-thiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene}amino)oxy]-2-methylpropanoic acid
- 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
- Antibiotic Squibb 26,776
- Azonam
- Azthreonam
- Aztreon
- Aztreonamo
- Monobactam
- Nebactam
- Primbactam
- Propanoic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methyl-
- Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2R-[2α,3α(Z)]]-
- Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2S-[2α,3β(Z)]]-
- Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2α,3β(Z)]-
- Sq 26776
- Squibb 26776
- See more synonyms
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Found 15 products.
Aztreonam
CAS:Formula:C13H17N5O8S2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:435.43Aztreonam
CAS:<p>Aztreonam is used to treat severe infections of the urinary tract, lower respiratory tract, skin, stomach, female reproductive organs, and other body systems. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label informat</p>Formula:C13H17N5O8S2Color and Shape:White to yellow crystalline powderMolecular weight:435.43Aztreonam
CAS:<p>Antibiotics nesoi</p>Formula:C13H17N5O8S2Color and Shape:White Off-White Crystalline PowderMolecular weight:435.051852-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
CAS:Formula:C13H17N5O8S2Purity:90%Color and Shape:SolidMolecular weight:435.4328Aztreonam
CAS:<p>Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.</p>Formula:C13H17N5O8S2Purity:97.6% - >99.99%Color and Shape:SolidMolecular weight:435.43Aztreonam
CAS:Formula:C13H17N5O8S2Purity:95.0 - 105.0 % (dried basis)Color and Shape:White to off-white crystalline powderMolecular weight:435.43Aztreonam, USP grade
CAS:Formula:C13H17N5O8S2Purity:≤ 1.5%Color and Shape:White to off-white crystalline powderMolecular weight:435.43Aztreonam
CAS:Controlled Product<p>Applications The first totally synthetic monocyclic β-lactam antibiotic.<br>References Sykes, R.B., et al.: Antimicrob. Agents Chemother., 21, 85 (1982), Florey, K., et al.: Anal. Profiles Drug Subs., 17, 1 (1988),<br></p>Formula:C13H17N5O8S2Color and Shape:WhiteMolecular weight:435.43Aztreonam
CAS:<p>A β-lactam antibiotic of monobactam subclass, which targets peptidoglycan synthesis in bacterial cell wall. Aztreonam is effective against Gram-negative aerobic bacteria and is more resistant to β-lactamases than other β-lactam antibiotics.</p>Formula:C13H17N5O8S2Purity:Min. 97 Area-%Color and Shape:White Off-White PowderMolecular weight:435.43 g/molAztreonam (AZN), 96%
CAS:Formula:C13H17N5O8S2Purity:min. 96.0%Color and Shape:White to light yellow, Powder, Clear, Colourless to pale yellowMolecular weight:435.43Aztreonam, Antibiotic for Culture Media Use Only
CAS:<p>Please enquire for more information about Aztreonam, Antibiotic for Culture Media Use Only including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C13H17N5O8S2Purity:94 To 102%Molecular weight:435.43 g/mol
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