CAS: 78110-38-0 - Aztreonam

Formula: C₁₃H₁₇N₅O₈S₂

InChI: InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1

InChI key: InChIKey=WZPBZJONDBGPKJ-VEHQQRBSSA-N

SMILES: O=C(O)C(ON=C(C(=O)NC1C(=O)N(C1C)S(=O)(=O)O)C=2N=C(SC2)N)(C)C

Synonyms:

• (2S,3S)-3-({(2E)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-2-methyl-4-oxoazetidine-1-sulfonate
• (2S-(2-Alpha,3-Beta(Z)))-Dinyl)Amino)-2-Oxoethylidene)Amino)Oxy)-2-Methyl
• 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
• 2-({[1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
• 2-[({(1E)-1-(2-amino-1,3-thiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene}amino)oxy]-2-methylpropanoic acid
• 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
• Antibiotic Squibb 26,776
• Azonam
• Azthreonam
• Aztreon
• Aztreonamo
• Monobactam
• Nebactam
• Primbactam
• Propanoic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methyl-
• Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2R-[2α,3α(Z)]]-
• Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2S-[2α,3β(Z)]]-
• Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2α,3β(Z)]-
• Sq 26776
• Squibb 26776
• [2S-[2A,3B(Z)]]-2-[[[1-(2-Amino-4-Thiazolyl)-2-[(2-Methyl-4-Oxo-1-Sulfo-3-Azetidinyl)Amino]-2-Oxoethylidene]Amino]Oxy]-2-Methylpropanoic Acid

Aztreonam

CAS: 78110-38-0

• Formula: C₁₃H₁₇N₅O₈S₂
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 435.43

Aztreonam

CAS: 78110-38-0

Aztreonam is used to treat severe infections of the urinary tract, lower respiratory tract, skin, …

• Formula: C₁₃H₁₇N₅O₈S₂
• Color and Shape: White to yellow crystalline powder
• Molecular weight: 435.43

Aztreonam

CAS: 78110-38-0

Antibiotics nesoi

• Formula: C₁₃H₁₇N₅O₈S₂
• Color and Shape: White Off-White Crystalline Powder
• Molecular weight: 435.05185

2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid

CAS: 78110-38-0

• Formula: C₁₃H₁₇N₅O₈S₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 435.4328

Aztreonam

CAS: 78110-38-0

Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.

• Formula: C₁₃H₁₇N₅O₈S₂
• Purity: 99.42%
• Color and Shape: Solid
• Molecular weight: 435.43

Aztreonam

CAS: 78110-38-0

• Formula: C₁₃H₁₇N₅O₈S₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 435.43

Aztreonam, USP grade

CAS: 78110-38-0

• Formula: C₁₃H₁₇N₅O₈S₂
• Purity: ≤ 1.5%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 435.43

Aztreonam

CAS: 78110-38-0

• Formula: C₁₃H₁₇N₅O₈S₂
• Purity: 95.0 - 105.0 % (dried basis)
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 435.43

Aztreonam

CAS: 78110-38-0

• Formula: C₁₃H₁₇N₅O₈S₂
• Color and Shape: White
• Molecular weight: 435.43

Aztreonam

CAS: 78110-38-0

Applications The first totally synthetic monocyclic β-lactam antibiotic. References Sykes, R.B., et al.: Antimicrob. Agents …

• Formula: C₁₃H₁₇N₅O₈S₂
• Color and Shape: White
• Molecular weight: 435.43

Aztreonam

CAS: 78110-38-0

A β-lactam antibiotic of monobactam subclass, which targets peptidoglycan synthesis in bacterial cell wall. Aztreonam …

• Formula: C₁₃H₁₇N₅O₈S₂
• Purity: Min. 97 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 435.43 g/mol

Aztreonam (AZN), 96%

CAS: 78110-38-0

• Formula: C₁₃H₁₇N₅O₈S₂
• Purity: min. 96%
• Color and Shape: White to yellowish, Powder
• Molecular weight: 435.43