CAS 78832-65-2

N-(3-(2-furyl)acryloyl)-L-leucyl-glycyl-L-prolyl-L-alanine

Description:

N-(3-(2-furyl)acryloyl)-L-leucyl-glycyl-L-prolyl-L-alanine, with the CAS number 78832-65-2, is a synthetic peptide derivative that incorporates both amino acid sequences and a furan-based moiety. This compound features a unique structure that combines the properties of a peptide with those of an acrylamide, which may impart specific reactivity and biological activity. The presence of the furan ring suggests potential for interactions with biological systems, possibly influencing its pharmacological properties. The amino acid components—L-leucine, glycine, L-proline, and L-alanine—contribute to the compound's stability and solubility, while also affecting its conformational characteristics. Such peptides can exhibit various biological activities, including antimicrobial, anticancer, or enzyme-inhibitory effects, depending on their structure and the specific interactions they engage in. Overall, this compound represents a fascinating intersection of organic chemistry and biochemistry, with potential applications in drug development and therapeutic research.

Formula: C₂₃H₃₂N₄O₇

InChI: InChI=1/C23H32N4O7/c1-14(2)12-17(26-19(28)9-8-16-6-5-11-34-16)21(30)24-13-20(29)27-10-4-7-18(27)22(31)25-15(3)23(32)33/h5-6,8-9,11,14-15,17-18H,4,7,10,12-13H2,1-3H3,(H,24,30)(H,25,31)(H,26,28)(H,32,33)/b9-8+/t15-,17-,18-/m0/s1

Synonyms:

• N-(3-(2-furyl)acryloyl)-leu-gly-pro-ala
• FA-Leu-Gly-Pro-Ala-OH
• Falgpa
• N-[(2E)-3-furan-2-ylprop-2-enoyl]-L-leucylglycyl-L-prolyl-L-alanine
• COLLAGENASE CELL PREPARATION GRADE
• COLLAGENASE GRADE II
• COLLAGENASE GRADE I
• clostridiopeptidase
• CollagenaseⅡ
• N-[3-(2-FURYL)ACRYLOYL]-L-LEUCYL-GLYCYL-L-PROLYL-L-ALANINE
• (2S)-3-{2-[(1E)-2-{[(1S)-1-({2-[(2S)-2-{[(1S)-1-carboxyethyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}carbamoyl)-3-methylbutyl]carbamoyl}eth-1-en-1-yl]-1λ3-furan-1-yl}-2-{[(2S)-1-{2-[(2S)-2-[(2E)-3-(furan-2-yl)prop-2-enamido]-4-methylpentanamido]acetyl}pyrro
• N-[3-(2-furyl)acryloyl]-leucine-glycine-proline-alanine
• N-(3-(2-FURYL)ACRYLOYL)-L-LEUCYL-GLYCYL&
• N-{3-(2-Furyl)acryloyl}-L-leucine-glycyl-L-propyl-L-alanine
• FALGPA, N-[3-(2-Furyl)acryloyl]-L-leucyl-glycyl-L-prolyl-L-alanine
• COLLAGENASE SUBSTRATE II
• COLLAGENASE HIGHLY PURIFIED
• CollagenaseⅠ
• CollagenaseⅤ
• CollagenaseⅣ
• 2-furanacryloyl-leucyl-glycyl-prolyl-alanine
• COLLAGENASE (CLOSTRIDIOPEPTIDASE A)

FA-Leu-Gly-Pro-Ala-OH

CAS: 78832-65-2

Substrate for a versatile, convenient, continuously recording spectrophotometric assay of collagenase.

Formula: C₂₃H₃₂N₄O₇

Purity: 97.7%

Color and Shape: Beige

Molecular weight: 476.53

Ref: 01-4006713

L-ALANINE,N-[3-(2-FURANYL)-1-OXO-2-PROPEN-1-YL]-L-LEUCYLGLYCYL-L-PROLYL-

CAS: 78832-65-2

Formula: C₂₃H₃₂N₄O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 476.5228

Ref: IN-DA005DFG

FA-Leu-Gly-Pro-Ala-O

CAS: 78832-65-2

FA-Leu-Gly-Pro-Ala-OH is a synthetic peptide and a specific collagenase substrate, widely used in biochemical experiments and drug synthesis research.

Formula: C₂₃H₃₂N₄O₇

Purity: 99.90%

Color and Shape: Soild

Molecular weight: 476.52

Ref: TM-T205939

FALGPA

CAS: 78832-65-2

FALGPA

Formula: C₂₃H₃₂N₄O₇

Purity: By hplc: >98% by area (Typical Value in Batch COA)

Color and Shape: white to off white powder

Molecular weight: 476.52277g/mol

Ref: 54-BIF0744

FA-Leu-Gly-Pro-Ala-OH

CAS: 78832-65-2

FA-Leu-Gly-Pro-Ala-OH is a gelatinase inhibitor that inhibits the action of collagenase, an enzyme that breaks down collagen. It has been shown to inhibit the growth of cancer cells in vitro and may be useful as a therapeutic agent against skin cancer. FA-Leu-Gly-Pro-Ala-OH binds to the active site of the enzyme and blocks its catalytic activity by preventing proton transfer during the hydrolysis of peptide bonds. This inhibitor also has proteolytic properties, which are due to its ability to cleave proteins with basic amino acids such as arginine and lysine. The inhibitory effects of FA-Leu-Gly-Pro-Ala-OH on histological analysis were also tested on fibroblast cells with collagenase activity, which showed a significant reduction in enzyme activity after incubation with this inhibitor.

Formula: C₂₃H₃₂N₄O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 476.52 g/mol

Ref: 3D-FF110857