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CAS 78842-13-4

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2'-Deoxy-2'-fluoroguanosine

Description:
2'-Deoxy-2'-fluoroguanosine is a modified nucleoside that serves as an analog of guanosine, where the hydroxyl group at the 2' position of the ribose sugar is replaced by a fluorine atom. This modification can influence the nucleoside's biochemical properties, including its stability and interaction with nucleic acids. The presence of the fluorine atom enhances resistance to enzymatic degradation, making it a valuable compound in medicinal chemistry and molecular biology, particularly in the development of antiviral and anticancer agents. 2'-Deoxy-2'-fluoroguanosine can be incorporated into DNA, potentially altering the structure and function of the resulting nucleic acid. Its unique characteristics make it a subject of interest in research focused on nucleic acid analogs, as well as in the design of therapeutic agents that target specific biological pathways. Additionally, its CAS number, 78842-13-4, allows for easy identification and reference in scientific literature and databases.
Formula:C10H12FN5O4
InChI:InChI=1/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1
SMILES:C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2[nH]c(=N)nc3O)O1)F)O)O
Synonyms:
  • 2'-FdG
  • 2'-Fluoro-2'-deoxyguanosine
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