CAS 79-61-8

Dichlorisone acetate

Description:

Dichlorisone acetate, with the CAS number 79-61-8, is a synthetic organic compound that belongs to the class of corticosteroids. It is characterized by its anti-inflammatory and immunosuppressive properties, making it useful in various pharmaceutical applications, particularly in dermatology for treating skin conditions. The compound typically appears as a white to off-white crystalline powder and is soluble in organic solvents but has limited solubility in water. Its chemical structure features a dichlorinated phenolic ring, which contributes to its biological activity. Dichlorisone acetate is often used in formulations for topical administration, allowing for localized treatment with reduced systemic effects. As with many corticosteroids, it may have side effects, including skin irritation or atrophy with prolonged use. Safety and handling precautions are essential due to its potential effects on human health and the environment. Overall, dichlorisone acetate is a valuable compound in medicinal chemistry, particularly for its therapeutic applications in managing inflammatory conditions.

Formula: C₂₃H₂₈Cl₂O₅

InChI: InChI=1S/C23H28Cl2O5/c1-13(26)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(27)6-8-20(14,2)23(17,25)18(24)11-21(16,22)3/h6,8,10,16-18,29H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1

InChI key: InChIKey=YNNURTVKPVJVEI-GSLJADNHSA-N

SMILES: Cl[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1Cl)[C@](C(COC(C)=O)=O)(O)CC3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (11Beta)-9,11-Dichloro-17-Hydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (11beta)-21-(Acetyloxy)-9,11-dichloro-17-hydroxypregna-1,4-diene-3,20-dione
• (11β)-21-(Acetyloxy)-9,11-dichloro-17-hydroxypregna-1,4-diene-3,20-dione
• (8Xi,10Xi,13Xi,14Xi)-9,11-Dichloro-17-Hydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• 9alpha,11beta-Dichloro-17alpha,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate
• 9α,11β-Dichloro-21-acetoxypregna-1,4-dien-17α-ol-3,20-dione
• Astroderm
• Cloriderm
• Dermocid
• Dichlorisona
• Dichlorisone-21-acetate
• Diclorisona
• Diloderm
• Disoderm
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11beta)-
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11β)-
• Pregna-1,4-diene-3,20-dione, 9,11β-dichloro-17,21-dihydroxy-, 21-acetate
• Visoderm
• delta1-9,11-Dichlorocortisone acetate
• Δ¹-9,11-Dichlorocortisone acetate
• Dichlorisone acetate

Dichlorisone Acetate

CAS: 79-61-8

Dichlorisone Acetate (Diloderm) is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.

Formula: C₂₃H₂₈Cl₂O₅

Purity: 98.69% - 99.51%

Color and Shape: Solid

Molecular weight: 455.37

Ref: TM-T0269

Dichlorisone Acetate

CAS: 79-61-8

Dichlorisone Acetate

Purity: ≥98%

Molecular weight: 455.37g/mol

Ref: 54-BUP14459

Dichlorisone acetate

Controlled Product

CAS: 79-61-8

Dichlorisone acetate is a pharmaceutical preparation that is used as a local anesthetic and anti-inflammatory agent. Dichlorisone acetate is applied topically to the skin and mucous membranes, or injected into tissue for surgical use. It is also used to reduce swelling in various inflammatory diseases. Dichlorisone acetate has been shown to be effective against cancer cells, with the most significant effect on tumor cells in blood vessels or tissues. The mechanism of action of dichlorisone acetate involves reducing the amount of chloride ions in the extracellular matrix, which decreases cell proliferation and increases cell death (apoptosis).

Formula: C₂₃H₂₈Cl₂O₅

Purity: Min. 95%

Molecular weight: 455.37 g/mol

Ref: 3D-AAA07961