CAS 797-63-7

Levonorgestrel

Description:

Levonorgestrel is a synthetic progestin, primarily used in hormonal contraceptives and emergency contraception. It is characterized by its ability to inhibit ovulation, thicken cervical mucus, and alter the endometrial lining, thereby preventing pregnancy. Chemically, it is a derivative of norethisterone and belongs to the class of compounds known as 19-nortestosterone derivatives. Levonorgestrel is typically administered in various forms, including oral tablets, intrauterine devices (IUDs), and implants. Its molecular formula is C21H28O2, and it has a relatively high lipophilicity, which contributes to its effectiveness and duration of action in the body. The substance is generally well-tolerated, but it can have side effects such as nausea, headache, and changes in menstrual bleeding patterns. Levonorgestrel is also used in combination with estrogen in some contraceptive formulations. Its mechanism of action and pharmacokinetics make it a crucial component in reproductive health management.

Formula: C₂₁H₂₈O₂

InChI: InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1

InChI key: InChIKey=WWYNJERNGUHSAO-XUDSTZEESA-N

SMILES: C(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (-)-Norgestrel
• (14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
• (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
• 13-Ethyl-17-Alpha-Ethynyl-17-Beta-Hydroxy-4-Gonen-3-One
• 13-Ethyl-17-Alpha-Ethynylgon-4-En-17-Beta-Ol-3-One
• 13-Ethyl-17-Hydroxy-19-Dinor-17-Alpha-Pregn-4-En-20-Yn-3-On(+)-1
• 13-Ethyl-17-ethynyl-17β-hydroxy-4-gonen-3-one
• 13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one
• 13-Ethyl-17α-ethynyl-17-hydroxygon-4-en-3-one
• 13-Ethyl-17α-ethynylgon-4-en-17β-ol-3-one
• 13β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one
• 17-Alpha-Ethinyl-13-Beta-Ethyl-17-Beta-Hydroxy-4-Estren-3-One
• 17-Beta-Hydroxy-18-Methyl-19-Nor-17-Alpha-Pregn-4-En-20-Yn-3-One
• 17-Ethynyl-18-Methyl-19-Nortestosteron
• 17-Ethynyl-18-Methyl-19-Nortestosterone
• 17α-Ethynyl-13-ethyl-19-nortestosterone
• 17α-Ethynyl-13β-ethyl-3-oxo-4-estren-17β-ol
• 17α-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one
• 17α-Ethynyl-18-homo-19-nortestosterone
• 17α-Ethynyl-18-methyl-19-nortestosterone
• 17β-Hydroxy-18-methyl-19-nor-17α-pregn-4-en-20-yn-3-one
• 18,19-Dinor-17α-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-
• 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-
• 18-Methyl-17-Alpha-Ethynyl-19-Nortestosterone
• 18-Methyl-17α-ethynyl-19-nortestosterone
• 18-Methylnorethindrone
• 19-Nortestosterone, 17-ethynyl-18-methyl-
• <span class="text-smallcaps">D</span>-(-)-Norgestrel
• D-(-)-Norgestrel
• Dexnorgestrel
• Femilis
• Femilis Slim
• Follistrel
• Jadelle
• Jaydess
• Levonorgestrel
• Levonova
• Lng-IUS
• Microlut
• Microluton
• Microval
• Mirena
• Norgeston
• Norgestrel (L-)
• Norgestrelem
• Norlevo
• Norplant
• Norplant 2
• Norplant II
• Plan B One-Step
• Postinor 2
• Sino-implant (II)
• Skyla
• Wy 5104

(-)-Norgestrel

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 312.45

Ref: 3B-N0889

LEVONORGESTREL (Ice shipment)

CAS: 797-63-7

Formula: C21H28O2

Ref: 23-PHR1850

LEVONORGESTREL CRS

CAS: 797-63-7

LEVONORGESTREL CRS

Formula: C₂₁H₂₈O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 312.4458

Ref: 41-L0551000

LEVONORGESTREL FOR SYSTEM SUITABILITY 1 CRS

CAS: 797-63-7

LEVONORGESTREL FOR SYSTEM SUITABILITY 1 CRS

Formula: C₂₁H₂₈O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 312.4458

Ref: 41-Y0001431

LEVONORGESTREL RS

CAS: 797-63-7

LEVONORGESTREL RS

Formula: C₂₁H₂₈O₂

Molecular weight: 312.4458

Ref: 41-ICRS0335

Levonorgestrel

CAS: 797-63-7

Levonorgestrel

Formula: C₂₁H₂₈O₂

Purity: 99.7%

Color and Shape: Off White Solid

Molecular weight: 312.20893

Ref: 47-501

LEVONORGESTREL FOR SYSTEM SUITABILITY 2 CRS

CAS: 797-63-7

LEVONORGESTREL FOR SYSTEM SUITABILITY 2 CRS

Formula: C₂₁H₂₈O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 312.4458

Ref: 41-Y0001618

Levonorgestrel

CAS: 797-63-7

Estrogens and progestins

Formula: C₂₁H₂₈O₂

Color and Shape: White Off-White Powder

Molecular weight: 312.20893

Ref: 45-1362602

Levonorgestrel

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Purity: %

Color and Shape: Solid

Molecular weight: 312.4458

Ref: IN-DA003AXC

Levonorgestrel

CAS: 797-63-7

Levonorgestrel (D-Norgestrel) is a Progestin and Progestin-containing Intrauterine Device.

Formula: C₂₁H₂₈O₂

Purity: 99.42% - 99.44%

Color and Shape: Crystals From Methanol Solid

Molecular weight: 312.45

Ref: TM-T1263

Levonorgestrel (D-(-)-Norgestrel), Etonogestrel EP Impurity G)

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Color and Shape: White To Off-White Solid

Molecular weight: 312.45

Ref: 4Z-L-223

Levonorgestrel

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Molecular weight: 312.45

Ref: 7W-GP0670

Levonorgestrel

CAS: 797-63-7

Levonorgestrel

Purity: 98%

Molecular weight: 312.45g/mol

Ref: 54-OR1029527

Levonorgestrel

CAS: 797-63-7

Levonorgestrel

Purity: ≥98%

Molecular weight: 312.45g/mol

Ref: 54-BUP17540

(-)-Norgestrel-2,2,4,6,6,10-d6

CAS: 2376035-98-0, 797-63-7

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 318.49

Ref: 3U-D6159

Levonorgestrel 100 µg/mL in Acetonitrile

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Color and Shape: Single Solution

Molecular weight: 312.45

Ref: 04-A14629760AL-100

Levonorgestrel

Controlled Product

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Color and Shape: Neat

Molecular weight: 312.45

Ref: 04-C14629760

Levonorgestrel

Controlled Product

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Color and Shape: Neat

Molecular weight: 312.45

Ref: 86-MM0121.00

D-(-)-Norgestrel

CAS: 797-63-7

Impurity Norgestimate USP Related Compound A
Applications D-(-)-Norgestrel is an emergency contraceptive. Levonorgestrel is safe, tolerated and effective in emergency contraception in woman. Norgestimate USP Related Compound A.
References Fotherby, K., et al.: J. Steroid Biochem., 19(1C), 817 (1983), Stanczyk, F. Z., et al.: Contraception, 42, 67 (1990),;

Formula: C₂₁H₂₈O₂

Color and Shape: Neat

Molecular weight: 312.45

Ref: TR-N689510

D-(-)-Norgestrel-d7

Controlled Product

CAS: 797-63-7

Applications An emergency contraceptive. Levonorgestrel is safe, tolerated and effective in emergency contraception in woman.
References Fotherby, K., et al.: J. Steroid Biochem., 19(1C), 817 (1983), Stanczyk, F. Z., et al.: Contraception, 42, 67 (1990), Bednarek, P., et al.: Drugs, 67, 2478 (2007),

Formula: C₂₁H₂₁D₇O₂

Color and Shape: Neat

Molecular weight: 319.49

Ref: TR-N689512